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What is the chemical structure of 6-Bromo-4- (6-fluoro-3-pyridinyl) pyrazolo [1,5-a] pyridine-3-carbonitrile
6 - Bromo - 4 - (6 - fluoro - 3 - pyridinyl) pyrazolo [1,5 - a] pyridine - 3 - carbonitrile is an organic compound. Looking at its name, the approximate chemical structure can be analyzed.
"6 - Bromo" shows that the compound is connected to a bromine atom at position 6. Bromine atom, a genus of halogen elements, has specific chemical activity. "4 - (6 - fluoro - 3 - pyridinyl) ", indicating that there is a 6 - fluoro - 3 - pyridinyl group connected at position 4. The 6-fluoro-3-pyridyl group has a fluorine atom attached to the pyridine ring at position 3, and the fluorine atom is also a halogen element, which has a unique electronic effect.
"pyrazolo [1,5-a] pyridine", which is a pyrazolo [1,5-a] pyridine structure, is formed by fusing the pyrazolo ring with the pyridine ring to form a unique conjugate system, which affects the physical and chemical properties of the compound. And "3-carbonitrile" indicates that there is a cyano (-CN) attached to the 3 position of the pyrazolo [1,5-a] pyridine. Cyanyl groups have strong polarity and have an important impact on the reactivity and biological activity of compounds.
In summary, the chemical structure of 6-Bromo-4- (6-fluoro-3-pyridinyl) pyrazolo [1,5-a] pyridine-3-carbonitrile is composed of pyrazolo [1,5-a] pyridine as the parent nucleus, and is composed of a bromine atom at position 6, a 6-fluoro-3-pyridinyl group at position 4, and a cyanide group at position 3. This structure endows the compound with specific chemical and physical properties.
What are the main uses of 6-Bromo-4- (6-fluoro-3-pyridinyl) pyrazolo [1,5-a] pyridine-3-carbonitrile
6 - Bromo - 4 - (6 - fluoro - 3 - pyridinyl) pyrazolo [1,5 - a] pyridine - 3 - carbonitrile is an organic compound. Its main uses are commonly found in the fields of medicinal chemistry and materials science.
In medicinal chemistry, this compound is often used as a lead compound. Due to its unique molecular structure, it has specific biological activities or can interact with specific targets in organisms. By adjusting its structure and changing its substituents, researchers can explore its affinity and selectivity for different biological targets, and then develop new drugs. For example, for some disease-related enzymes or receptors, the compound can be modified to obtain highly active and highly selective inhibitors or agonists, providing the possibility for innovative drug research and development.
In terms of materials science, this compound can be used to prepare functional materials due to its special electronic structure and chemical stability. For example, the pyridine and pyrazolo-pyridine parts in its structure may endow the material with unique photoelectric properties. It can be introduced into polymer systems to prepare polymer materials with special optical or electrical properties for use in organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices to improve device performance and efficiency. < Br >
Because of its bromine, fluorine and other halogen atoms, in organic synthesis chemistry, these halogen atoms can be used as reactive activity check points to participate in a variety of organic reactions, such as the coupling reaction of halogenated aromatics, etc., used to construct more complex organic molecular structures and expand the variety and application range of organic compounds.
6-Bromo-4- (6-fluoro-3-pyridinyl) pyrazolo [1,5-a] pyridine-3-carbonitrile
The synthesis of 6-bromo-4- (6-fluoro-3-pyridyl) pyrazolo [1,5-a] pyridine-3-formonitrile is a subject of considerable interest in organic synthetic chemistry. Its synthesis often requires delicate strategies and techniques.
A common method uses compounds containing pyridine and pyrazole structures as starting materials. Fluorination is carried out at specific positions on the pyridine ring first, and fluorine atoms can be introduced at the 6 position of the pyridine by means of nucleophilic substitution or other suitable fluorination methods. This step requires fine regulation of reaction conditions, such as temperature, solvent, and catalyst selection, to ensure the precise introduction of fluorine atoms and avoid side reactions.
Next, the pyrazole ring is constructed. The relevant precursor compounds can be cyclized to form pyrazole rings through suitable nitrogen-containing heterocyclic synthesis reactions, and attention should be paid to the check point of the connection between the pyrazole ring and the pyridine ring to ensure that the two are connected in the desired [1,5-a] way.
As for the introduction of cyanyl groups at the third position of the pyrazolopyridine structure, it may be achieved by nucleophilic substitution reaction. Select the appropriate cyanylation reagent, and under the appropriate reaction conditions, make it react with the intermediate to achieve the access of the cyanyl group. The introduction of bromine atoms at the 6 position can also choose suitable reactions such as electrophilic substitution to accurately place the bromine atoms at the target position.
During the synthesis process, each step of the reaction requires the separation and purification of the product. Column chromatography, recrystallization and other means are often used to ensure the purity of the intermediate and the final product, laying the foundation for subsequent reactions or applications. Optimization of reaction conditions at each step, such as precise control of the proportion of reactants, reaction time, temperature and catalyst dosage, is essential to improve the yield and selectivity. Thus, 6-bromo-4- (6-fluoro-3-pyridyl) pyrazolo [1,5-a] pyridyl-3-formonitrile can be successfully synthesized by multi-step delicate design and operation.
What are the physical properties of 6-Bromo-4- (6-fluoro-3-pyridinyl) pyrazolo [1,5-a] pyridine-3-carbonitrile
6 - Bromo - 4 - (6 - fluoro - 3 - pyridinyl) pyrazolo [1,5 - a] pyridine - 3 - carbonitrile is an organic compound with important physical properties and is widely used in chemical research and related fields.
Looking at its appearance, under normal circumstances, this compound is mostly white to light yellow crystalline powder. The powder is fine in texture, and when the light shines, the surface may be slightly shiny, just like the early morning sun shining on the fine sand. This appearance characteristic not only makes it easy to recognize visually, but also has a profound impact on its subsequent processing and application. For example, in the preparation process, the fluidity and dispersibility of the powder are closely related to the appearance and morphology, which is related to the quality and stability of the product.
When it comes to the melting point, the melting point of this compound is about [X] ° C. The melting point is like the "temperature marker" of a substance, which is an important physical constant. When the temperature gradually rises to the melting point, the thermal motion of the compound molecules intensifies, and the lattice structure begins to disintegrate, transforming from a solid state to a liquid state. Knowing the melting point accurately is of great significance for the determination of the purity of the compound. If the melting point is accurate and the melting range is narrow, it can indicate that the purity is higher; conversely, the melting range may contain impurities and needs to be further purified.
In terms of solubility, the compound exhibits good solubility in organic solvents such as dichloromethane and N, N-dimethylformamide (DMF). In dichloromethane, it is like a snowflake integrated into warm water, rapidly dispersed and dissolved to form a homogeneous solution. In water, its solubility is poor, like a stone thrown into water, and it is difficult to blend with water. This solubility characteristic plays a key role in the separation, purification and selection of reaction media of compounds. In organic synthesis reactions, the selection of suitable solvents has a significant impact on the reaction process and product yield.
In addition, its density is about [X] g/cm ³. The density reflects the mass per unit volume of the substance and is related to other physical properties. In terms of storage and transportation, density data can help to rationally plan packaging and storage space to ensure safe and efficient operation.
In conclusion, the physical properties of 6-Bromo-4- (6-fluoro-3-pyridinyl) pyrazolo [1,5-a] pyridine-3-carbonitrile are like keys, opening doors for its application and exploration in chemical research, drug synthesis, materials science and other fields.
6-Bromo-4- (6-fluoro-3-pyridinyl) pyrazolo [1,5-a] pyridine-3-carbonitrile
6-Bromo-4- (6-fluoro-3-pyridyl) pyrazolo [1,5-a] pyridine-3-formonitrile, an organic compound. In the current market outlook, it has a multi-faceted situation.
In the field of medicine, such compounds with nitrogen-containing heterocyclic structures often have diverse biological activities, or can become key intermediates for the development of new drugs. With the advance of medical technology, the exploration of novel drug molecules is on the rise, and the demand for compounds with unique structures and potential activities may grow. If the current research and development of anti-cancer and antiviral drugs is in full swing, the compound will have a broad market prospect if it is further studied and modified, or if it finds a place for application.
In the field of materials science, organic optoelectronic materials have developed rapidly. Compounds containing specific heterocyclic structures, or due to their unique electronic structures, exhibit good optoelectronic properties. If 6-bromo-4- (6-fluoro-3-pyridyl) pyrazolo [1,5-a] pyridyl-3-formonitrile has been confirmed to have such properties, it may be applied in the preparation of organic Light Emitting Diodes, solar cells and other materials, thus opening up new markets.
However, its market prospects are not entirely smooth. The development and production of organic compounds often requires complicated processes. From laboratory synthesis to large-scale production, many technical problems need to be overcome, such as yield improvement, purity assurance, cost control, etc. And the market competition is fierce. Compounds of the same kind or similar functions may already exist in the market. To stand out, they need to have significant advantages in performance and cost.
In summary, the market prospects for 6-bromo-4- (6-fluoro-3-pyridyl) pyrazolo [1,5-a] pyridyl-3-formonitrile present opportunities and challenges. If we can break through technical barriers, give full play to structural advantages, or make great achievements in the fields of medicine and materials, we will open up a broad market space.