6-bromo-1H-pyrrolo[3,2-b]pyridine

6-Bromo-1H-pyrrolo [3,2-b] pyridine is an organic compound, and its chemical properties are interesting and worth exploring.
From a structural point of view, this compound contains bromine atoms and a specific pyrrolido-pyridine skeleton. The introduction of bromine atoms endows it with unique reactivity. Due to the high electronegativity of bromine atoms, it can change the electron cloud density of ortho and para-sites, thereby affecting the check point of electrophilic substitution reactions. For example, in electrophilic substitution reactions, the ortho and para-sites of bromine atoms are vulnerable to electrophilic attack because they can disperse positive charges by means of resonance effects, which is beneficial for the reaction to proceed.
The nitrogen atom of this compound also has important chemical properties. The nitrogen atoms in the pyrrole ring and pyrrole ring both have solitary pairs of electrons. The solitary pairs of electrons of the pyrrole nitrogen atom do not participate in the conjugation system and have a certain alkalinity, which can react with acids to form salts. The solitary pairs of electrons of the pyrrole nitrogen atom participate in the conjugation, and the alkalinity is weak, but the electron cloud density of the pyrrole ring increases, and the electrophilic substitution reaction is more likely to occur.
In terms of redox reaction, the pyridine ring of 6-bromo-1H-pyrrolo [3,2-b] pyridine can be moderately oxidized to form pyridine-N-oxide derivatives. This process changes the molecular electron distribution and polarity, and affects its reactivity and physical properties. At the same time, the unsaturated bonds in the molecule can be reduced. For example, under suitable catalyst and reaction conditions, the double bonds of the pyridine ring or pyrrole ring can be hydrogenated and reduced, resulting in significant changes in the structure and properties of the compounds.
In the field of organic synthesis, the bromine atom of 6-bromo-1H-pyrrolo [3,2-b] pyridine is an important functional group. It can react with various nucleophilic reagents such as alcohols, amines, mercaptan, etc. through nucleophilic substitution reactions to form carbon-heteroatomic bonds and synthesize derivatives with diverse structures. It has wide application prospects in pharmaceutical chemistry, materials science and other fields.
In summary, 6-bromo-1H-pyrrolo [3,2-b] pyridine is rich in chemical properties due to its unique structure and plays an important role in many fields of organic chemistry, providing key structural units for the synthesis of new functional materials and drugs.

6-Bromo-1H-pyrrolo [3,2-b] pyridine is an important organic compound, and its common synthesis methods are as follows:
The starting material is often a compound containing pyridine and pyrrole structures. One method is to use a suitable pyridine derivative as a base, under specific conditions, introduce a pyrrole ring, and precisely introduce a bromine atom at a specific position in the pyrrole ring. In this case, the control of the reaction conditions is the key.
If 2-aminopyridine is used as the starting material, first react with a suitable halogenated hydrocarbon under the catalysis of a base to form a substituted derivative of the pyridine ring. This step requires attention to the amount of base, reaction temperature and time. If the amount of alkali is too small, the reaction is difficult to be sufficient; if it is too much, it may lead to side reactions. If the temperature is too high, the product may decompose; if it is too low, the reaction rate will be slow.
Then, the pyridine ring is merged with the pyrrole ring through a specific reaction. This process can be achieved by condensation reaction, which often requires the help of a catalyst. The activity and selectivity of the catalyst affect the reaction effect. High activity, which can accelerate the reaction; good selectivity, high purity target product can be obtained.
There are also those who use pyrrole derivatives as the starting material, first modify the pyrrole ring, and then connect it with the pyridine related fragments. In such reactions, the use of protective groups is indispensable. Protect specific functional groups to prevent unnecessary reactions in the reaction, and then deprotect the group at a suitable stage to obtain the target product 6-bromo-1H-pyrrolo [3,2-b] pyridine.
After each step of the reaction, the separation and purification of the product are also important. High purity 6-bromo-1H-pyrrolo [3,2-b] pyridine is often obtained by column chromatography, recrystallization, etc., to meet the needs of subsequent research and application. In this way, this important organic compound can be obtained through fine design and operation.

6-Bromo-1H-pyrrolo [3,2-b] pyridine is a special organic compound that has applications in many fields.
In the field of medicinal chemistry, its application is crucial. Due to its unique chemical structure, it can be used as an intermediate for drug synthesis. By modifying and modifying its structure, drug molecules with specific biological activities can be developed. For example, it may be used to create small molecule inhibitors targeting specific disease-related targets, such as some cancer-related kinases, which inhibit kinase activity by binding to kinase activity check points, thereby hindering the proliferation and metastasis of cancer cells, providing new opportunities for cancer treatment.
In the field of materials science, 6-bromo-1H-pyrrolo [3,2-b] pyridine also has its uses. It can participate in the synthesis of functional materials, such as organic optoelectronic materials. Because of its conjugated structure, it may endow materials with special optical and electrical properties, such as in the preparation of organic Light Emitting Diodes (OLEDs), which improve their luminous efficiency and stability, and contribute to the development of display technology; or in the preparation of organic solar cell materials, which enhance the ability to absorb light and transport charge, and improve the photoelectric conversion efficiency of solar cells.
In the field of organic synthetic chemistry, this compound is often used as a key starting material or intermediate. Its bromine atom and pyridine-pyrrole structure can participate in a variety of organic reactions, such as nucleophilic substitution reactions, metal catalytic coupling reactions, etc. Through these reactions, more complex organic molecular structures can be constructed, the boundaries of organic synthetic chemistry can be expanded, and organic compounds with novel structures and properties can be synthesized to promote the development of organic chemistry.

6 - bromo - 1H - pyrrolo [3,2 - b] pyridine is an organic compound. Its physical properties are as follows:
Under normal temperature and pressure, this compound is mostly solid. Its color is usually white to light yellow powder, with a delicate appearance and uniform quality.
In terms of melting point, the melting point of this substance is quite critical, between 145 ° C and 149 ° C. This melting point range allows it to transform from solid to liquid under specific temperature conditions. When the temperature gradually rises to the lower limit of the melting point range, the thermal motion of the molecule intensifies, the lattice structure begins to loosen, and then gradually melts.
Solubility is also an important physical property. 6-Bromo-1H-pyrrolo [3,2-b] pyridine is insoluble in water, because water is a polar solvent, and the molecular structure of this compound is relatively weak in polarity. According to the principle of "similar miscibility", the two are difficult to dissolve each other. However, it has different behaviors in organic solvents. For example, in common organic solvents dichloromethane, N, N-dimethylformamide (DMF), it has certain solubility. In dichloromethane, it can partially dissolve to form a uniform dispersion system; in DMF, it has better solubility and can dissolve well, providing a homogeneous reaction environment for organic synthesis reactions.
In addition, the compound has a relatively high density, slightly higher than water. This shows that under the same volume, its mass is heavier than water. Its density data has important guiding significance for the measurement and separation of materials in chemical production and experimental operations.
Furthermore, its stability is acceptable under conventional conditions. However, it should be noted that due to its bromine atom and specific heterocyclic structure, under extreme conditions such as high temperature, strong acid and strong base, the structure may change, resulting in changes in chemical properties.

The question you are asking is about the market price of 6-bromo-1H-pyrrolo [3,2-b] pyridine. However, the price of these chemicals often changes from time to time and is also influenced by many factors, making it difficult to answer directly.
The previous author, "Tiangong Kaiwu", described the craftsmanship of hundreds of workers and the rheology of products, all vary from time to place. The same is true for the price of this 6-bromo-1H-pyrrolo [3,2-b] pyridine. The difficulty of its preparation, the abundance of raw materials, and the amount of demand are all reasons for the fluctuation of prices.
If the preparation is complex, it requires fine materials, and the cost will be high, and its price will be high. If the raw materials are scarce, it is difficult to find them, and it will cost money to obtain them, and the price will also rise accordingly. And if there are many people in the market who are seeking them, the supply is in short supply, and the merchants will raise their prices; on the contrary, there are few people seeking them, and the supply exceeds the demand, the price will drop.
And the trade situation in different places is different, and the freight between far and near also affects the price. In the land of the capital, the merchants converge, or the price is flat due to competition; in remote places, the transshipment is difficult, and the price may be high.
If you want to know the exact price, you should consult the market of chemical raw materials, the merchants who specialize in it, or the platform of the chemical trade you visit, and use the real-time market as the basis to obtain the near-real price. The market price of this 6-bromo-1H-pyrrolo [3,2-b] pyridine should not be based on speculation alone, but on current information.