6 Bromo 1 Chloro 1 Benzothieno 2 3 C Pyridine
pyridine pyrrole pyrazine piperidine piperazine

6-Bromo-1-chloro[1]benzothieno[2,3-c]pyridine

    Specifications

    HS Code

    412743

    Name 6-Bromo-1-chloro[1]benzothieno[2,3-c]pyridine
    Molecular Formula C11H5BrClNS
    Molecular Weight 308.59
    Appearance Solid (predicted)
    Boiling Point Predicted to be high due to its aromatic nature
    Solubility Poorly soluble in water, may be soluble in organic solvents like dichloromethane, chloroform
    Stability Stable under normal conditions, but reactive to strong oxidizing or reducing agents
    Pka No data available (but can be acidic or basic depending on reaction conditions)

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    Where to Buy 6-Bromo-1-chloro[1]benzothieno[2,3-c]pyridine in China?
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    Frequently Asked Questions

    As a leading 6-Bromo-1-chloro[1]benzothieno[2,3-c]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine
    6 - Bromo - 1 - chloro [1] benzothieno [2,3 - c] pyridine is an organic compound with a wide range of main uses. In the field of medicinal chemistry, this compound is often a key intermediate for the synthesis of drug molecules with specific biological activities. Due to its unique chemical structure, it can participate in a variety of chemical reactions, modified and transformed to generate drugs with high affinity and selectivity for specific disease targets.
    In the field of materials science, this compound may be used to prepare materials with special optoelectronic properties. Its structural properties may endow materials with unique electron transport and optical properties, which have made their mark in the fabrication of optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells, helping to improve device efficiency and stability.
    In addition, in the field of organic synthetic chemistry, 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine is an important starting material. With the help of various organic reactions, such as nucleophilic substitution reactions and metal catalytic coupling reactions, more complex organic molecular structures can be constructed, providing a key cornerstone for the creation of new organic compounds and promoting the development and innovation of organic synthetic chemistry.
    What are the synthesis methods of 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine
    6 - Bromo - 1 - chloro [1] benzothieno [2,3 - c] pyridine is an important organic compound, and its synthesis methods are diverse, so let me tell you one by one.
    First, benzothiophene and pyridine derivatives can be used as starting materials. First, benzothiophene is halogenated at a specific position and bromine atoms are introduced. This step requires precise control of the reaction conditions, such as reaction temperature, amount of halogenation reagent, etc., in order to locate the bromine atoms to the target position. Subsequently, the pyridine derivatives are suitably modified to have the activity to react with bromobenzothiophene. In the presence of a suitable catalyst, a coupling reaction occurs between the two to build the basic skeleton of the target molecule. In this process, the choice of catalyst is crucial, and different catalysts have a great influence on the reaction rate and yield.
    Second, it can also be synthesized by the strategy of intramolecular cyclization. Chain compounds with suitable substituents are selected and carefully designed to undergo intramolecular cyclization under specific reaction conditions. In this process, the electronic effect and steric resistance of the substituents are cleverly used to guide the reaction in the direction of generating 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine. For example, suitable nucleophiles and electrophiles are cyclized in the appropriate reaction medium to gradually form the thick ring structure of the target compound.
    Furthermore, the method of transition metal catalysis can be used. Transition metal catalysts, such as palladium and nickel, play an extraordinary role in organic synthesis. Substrates containing bromine and chlorine, catalyzed by transition metals, cooperate with aptamers to form carbon-carbon and carbon-heteroatomic bonds, and then achieve the synthesis of 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine. This method requires strict control of factors such as pH, temperature, catalyst and ligand ratio of the reaction system to obtain ideal results.
    In summary, the synthesis methods of 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine are rich and diverse, each with its own advantages and disadvantages and applicable scenarios. Researchers should carefully choose the appropriate synthesis path according to actual needs and conditions.
    What are the physical properties of 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine
    6 - Bromo - 1 - chloro [1] benzothieno [2,3 - c] pyridine is an organic compound whose physical properties are interesting and worthy of further investigation.
    The state of this compound is mostly solid at room temperature and pressure. Due to the relatively strong intermolecular forces and the orderly arrangement of atoms, the molecular motion is limited, so it presents a solid state. Looking at its appearance, it may be a white to light yellow crystalline powder, which may be related to the arrangement of atoms in the molecular structure and the distribution of electron clouds, which in turn affects the absorption and reflection of light, showing this color.
    In terms of melting point, it has been determined by many experiments to be in a certain temperature range. The melting point depends on the magnitude of the intermolecular forces. There are forces such as van der Waals forces and hydrogen bonds in the molecules of the compound. These forces hold the molecules tightly and require a specific energy to break them. The temperature corresponding to this specific energy is the melting point.
    Solubility is also an important physical property. In common organic solvents, such as dichloromethane, chloroform, etc., there is a certain solubility. Due to the principle of "similarity and miscibility", the molecular structure of the compound is similar to that of the organic solvent, and a certain interaction can be formed between the molecules to promote its dissolution. However, the solubility in water is poor, because water is a highly polar solvent, and the polarity of the compound is relatively weak, the intermolecular force between the two is difficult to overcome the hydrogen bond between water molecules, so it is not easily soluble in water.
    In addition, its density is also a key physical property. Although the exact value needs to be determined by precise experiments, the density range can be roughly inferred based on its molecular structure and relative molecular mass. The type and quantity of atoms in the molecular structure determine the relative molecular mass, which in turn affects the mass of the substance per unit volume, that is, the density.
    In conclusion, the physical properties of 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine, such as state, appearance, melting point, solubility, and density, are determined by its unique molecular structure, which is of great significance for in-depth understanding of the properties and applications of this compound.
    What are the chemical properties of 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine
    6 - Bromo - 1 - chloro [1] benzothieno [2,3 - c] pyridine is an organic compound with unique chemical properties. It contains bromine and chlorine atoms. Due to the strong electronegativity of halogen atoms, the compound has a certain polarity, which affects its physical and chemical behavior.
    From the perspective of physical properties, this compound has better solubility in organic solvents than in water due to molecular polarity. Its melting point and boiling point are affected by intermolecular forces. The introduction of halogen atoms will enhance the intermolecular forces, causing the melting point and boiling point to rise.
    When it comes to chemical properties, bromine and chlorine atoms are active check points. Bromine atoms can undergo nucleophilic substitution reactions, and nucleophilic test agents can attack carbon atoms connected to bromine and replace bromine atoms. If reacted with sodium alcohol, bromine atoms can be replaced by alkoxy groups to form corresponding ether compounds.
    Chlorine atoms are also similar and can participate in nucleophilic substitution. And because the benzothiophene pyridine ring system has a certain conjugate structure, the compound has a certain electron delocalization, which affects its reactivity. The electron cloud density distribution on the ring is affected by the induction effect of halogen atoms and the conjugation effect, resulting in different reactivity at different positions.
    In the aromatic electrophilic substitution reaction, the halogen atom is the o-and para-locator, which will cause the electrophilic reagent to attack the specific position on the benzothiophene pyridine ring and obtain the corresponding substituted product. The chemical properties of this compound are of great significance in the field of organic synthesis, and can be used as a key intermediate to construct more complex organic molecular structures through a series of reactions.
    How is the price of 6-Bromo-1-chloro [1] benzothieno [2,3-c] pyridine in the market?
    I searched for the price of various items in the market, but I didn't get the confirmed price of 6 - Bromo - 1 - chloro [1] benzothieno [2,3 - c] pyridine. This is a special chemical substance, and its price often changes for many reasons.
    First, the difference in quality affects the price. If the product has high purity and few impurities, it is suitable for high-end scientific research or fine chemical industry, and the price is not cheap; on the contrary, if the purity is slightly lower, it is only used for general experiments or basic chemical raw materials, and the price should be slightly reduced.
    Second, the state of supply and demand is related to the price. If there are many people who need it for a while, but there are few producers, the supply is in short supply, and the price will rise; if there is too much demand for production and the backlog in the market, the price will fall.
    Third, the difficulty of source and preparation also affects its price. If the preparation method is complicated, special raw materials and conditions are required, the cost is greatly increased, and the price is also high; if the preparation is relatively simple and the cost is controllable, the price may be close to the people.
    Fourth, the trend of market competition has an impact. If multiple competitors compete to produce this product, they are competing for market share, or there may be a price reduction; if it is operated exclusively, there is no worry about competition, and the price may be stable and high.
    Although I have not obtained the actual price, if you want to know the exact price of this product, you can consult the chemical reagent supplier, or check it in detail on the chemical product trading platform, or communicate with industry experts to obtain its near-real price.