As a leading 6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
6-BROMO-1,2,4-TRIAZOLO [4,3-1] What is the main use of PYRIDINE
6-Bromo-1,2,4-triazolo [4,3-a] pyridine is one of the organic compounds. Its main uses are quite extensive.
In the field of medicinal chemistry, it is often the key intermediate for the creation of new drugs. Due to the unique chemical structure and activity of this compound, a variety of biologically active derivatives can be derived by chemical modification. These derivatives may have various pharmacological activities such as antibacterial, antiviral, and anti-tumor, and are expected to be developed as new drugs for the treatment of specific diseases. For example, after research, it can be found that it has inhibitory effects on the growth of some tumor cells, providing new opportunities for the research and development of anti-tumor drugs.
In the field of materials science, 6-bromo-1,2,4-triazolo [4,3-a] pyridine also has potential applications. It can participate in the preparation of functional materials, such as photovoltaic materials. Due to its structure, it can affect the electronic transport and optical properties of materials. After rational design and synthesis, materials with specific photovoltaic properties may be prepared, which can be used in organic Light Emitting Diodes, solar cells and other devices to improve their performance and efficiency.
In the field of pesticide chemistry, this can be used as a raw material or can synthesize pesticides with high insecticidal and bactericidal activities. Its special structure can interact with specific targets in pests or pathogens, interfering with their physiological processes, achieving the purpose of controlling pests and diseases, assisting agricultural production to reduce losses, and ensuring crop harvests.
What are the physical properties of 6-BROMO-1,2,4-TRIAZOLO [4,3-1] PYRIDINE
6-Bromo-1,2,4-triazolo [4,3-a] pyridine, this is an organic compound. Its physical properties are quite important and are related to many practical applications.
Let's talk about the appearance first. Under normal temperature and pressure, 6-bromo-1,2,4-triazolo [4,3-a] pyridine often takes the shape of white to light yellow crystalline powder. This color and morphological characteristics can be used as an important basis for distinguishing and preliminarily judging its purity. In the laboratory, people can preliminarily determine whether the substance conforms to expectations by looking at its color and morphology with the naked eye.
Besides the melting point, the melting point of 6-bromo-1,2,4-triazolo [4,3-a] pyridine is within a specific range. Accurate determination of the melting point can provide key information for determining its purity and identifying the compound. Generally speaking, the melting point of pure products is relatively fixed. If it contains impurities, the melting point may change or the melting range may be wider.
Its solubility cannot be ignored. 6-bromo-1,2,4-triazolo [4,3-a] pyridine has some solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), etc. It has poor solubility in water. This solubility characteristic is of great significance in the separation, purification and solvent selection of compounds. For example, if you want to separate the compound from the mixture, you can choose a suitable solvent for extraction according to its solubility.
In addition, the density of 6-bromo-1,2,4-triazolo [4,3-a] pyridine is also one of its physical properties. Although density data are not as common as melting point and solubility in practical applications, density information is indispensable in specific scenarios, such as when it involves accurate measurement or phase equilibrium studies. Knowing its density can accurately calculate the relationship between substance dosage and volume, and ensure the smooth progress of the experiment or production process.
In summary, the physical properties of 6-bromo-1,2,4-triazolo [4,3-a] pyridine, such as appearance, melting point, solubility and density, play an important role in organic synthesis, drug development and materials science, and lay the foundation for related research and applications.
What are the chemical synthesis methods of 6-BROMO-1,2,4-TRIAZOLO [4,3-1] PYRIDINE
The chemical synthesis method of 6-bromo-1,2,4-triazolo [4,3-a] pyridine, although the ancient book "Tiangong Kaiwu" does not contain the method of synthesis of this substance, you can refer to the ancient chemical synthesis ideas.
To synthesize this substance, one can start with the construction of nitrogen-containing heterocyclic compounds. First find a suitable pyridine derivative, based on it, through halogenation reaction, the bromine atom is introduced into the specific position of the pyridine ring. In the halogenation reaction, select a suitable halogenation reagent and control the reaction conditions, such as temperature, solvent, catalyst, etc., so that the bromine atom precisely falls on the target check point to obtain the bromine-containing pyridine intermediate.
Second, construct the triazole ring structure. Using nitrogen-containing compounds as raw materials, through condensation and cyclization reactions, they are connected with the obtained bromine-containing pyridine intermediates to form a triazolo [4,3-a] pyridine structure. In this step, the ratio of reactants, the pH of the reaction environment, and the reaction time are all key.
Third, the reaction process needs to be finely regulated. Monitor the reaction process, use modern analytical methods, such as thin-layer chromatography, nuclear magnetic resonance, etc., to know the degree of reaction and product purity in real time. According to the monitoring results, adjust the reaction parameters to ensure the smooth synthesis route, and obtain high-purity 6-bromo-1,2,4-triazolo [4,3-a] pyridine. Although "Tiangong Kaiwu" does not cover this object, the principles of chemical synthesis are similar from ancient to modern, and according to this idea, it may be possible.
What is the price range of 6-BROMO-1,2,4-TRIAZOLO [4,3-1] PYRIDINE in the market?
What is the price of 6-bromo-1,2,4-triazolo [4,3-a] pyridine in the market? This is the key to fine chemistry, which is related to many chemical and pharmaceutical synthesis paths. It is not easy to determine its price, because its price often varies due to many factors.
The first to bear the brunt is the situation of supply and demand. If the market demands it, but the production is insufficient, the price will rise; conversely, if the supply exceeds the demand, the price may drop. In today's chemical and pharmaceutical fields, the demand for materials containing special nitrogen heterocyclic structures is increasing. 6-bromo-1,2,4-triazolo [4,3-a] pyridine is important for the development of new drugs and the preparation of special materials due to its unique structure, or the demand is greater than the supply, and the price is higher.
Furthermore, the cost of production is also a major factor. The price of raw materials, the simplicity of the production process, and the amount of energy consumption are all related to the cost. If raw materials are scarce and expensive, or production requires complicated steps and high-end equipment, the cost will increase, and the price will follow. The synthesis of 6-bromo-1,2,4-triazolo [4,3-a] pyridine involves a multi-step reaction, which requires strict reaction conditions, resulting in high costs, which is reflected in the selling price.
In addition, the quality grade also affects the price. Those with high purity are mostly used in high-end fields such as pharmaceutical research and development, and the price is higher than that of ordinary industrial grade. The price of the product on the market may vary due to different purity.
Overall, the price of 6-bromo-1,2,4-triazolo [4,3-a] pyridine in the market, if it is ordinary industrial grade, may reach several hundred yuan per kilogram; if it is high-purity pharmaceutical grade, it may reach tens of yuan per gram or even higher. However, this is only a rough estimate, and its true price should be investigated in detail according to the real-time market situation.
6-BROMO-1,2,4-TRIAZOLO [4,3-1] What are the manufacturers of PYRIDINE?
6-Bromo-1,2,4-triazolo [4,3-a] pyridine is produced by many manufacturers in today's chemical industry.
First of all, such as Warwick Pharmaceutical Technology Group, which has been deeply cultivated in the field of organic synthetic chemistry for many years and has a lot of background. The R & D team in the group is elite and well-equipped. It is also good at preparing 6-bromo-1,2,4-triazolo [4,3-a] pyridine.
Another example is the joint stock company of Medicine Stone Technology, which focuses on the research and development and production of pharmaceutical molecular blocks. The company adheres to the concept of innovation and has made many achievements in the creation of heterocyclic blocks. 6-Bromo-1,2,4-triazolo [4,3-a] pyridine is an important drug synthesis intermediate. Medicine Stone Technology continuously optimizes its production process, and the products are of high quality and sufficient quantity.
Overseas, Germany's Merck Group is a giant in the chemical and pharmaceutical industry. The group has a long history and deep technical precipitation. In the production of fine chemicals, its standards are strict and the craftsmanship is exquisite. The output of 6-bromo-1,2,4-triazolo [4,3-a] pyridine meets the international high-end market demand.
Sigma-Aldrich Company of the United States is famous for providing high-quality chemical reagents and intermediates. It has an outstanding position in the field of global chemical product supply. 6-Bromo-1,2,4-triazolo [4,3-a] pyridine is also one of its rich product lines, and its products are widely used in the R & D and production of scientific research institutions and enterprises.
Manufacturers, either by technology or according to scale, demonstrate their capabilities in the production of 6-bromo-1,2,4-triazolo [4,3-a] pyridine, and jointly promote the circulation and application of this product in the chemical and pharmaceutical industries.
