6 Aminopyridine 2 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

6-Aminopyridine-2-carboxylic acid

    Specifications

    HS Code

    488743

    Chemical Formula C6H6N2O2
    Molar Mass 138.124 g/mol
    Appearance Solid
    Melting Point 187 - 190 °C
    Solubility In Water Slightly soluble
    Pka1 2.63
    Pka2 4.82
    Density 1.371 g/cm³
    Flash Point 161.5 °C
    Cas Number 2722-57-8

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    General Information
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    Frequently Asked Questions

    As a leading 6-Aminopyridine-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 6-aminopyridine-2-carboxylic acids?
    6-Aminopurine-2-carboxylic acid, namely adenine-2-carboxylic acid, its chemical properties are as follows:
    This compound has the characteristics of both amino and carboxyl groups. From the perspective of amino groups, amino groups are alkaline and can react with acids. Under appropriate conditions, they can bind with protons to form a positively charged ammonium ion structure. For example, in the case of strong acids, the lone pair electrons on the amino nitrogen atom can accept protons and undergo protonation reactions to generate relatively stable cations.
    The carboxyl group is acidic and has the common property of acids. It can partially ionize hydrogen ions in water, showing acidic characteristics. It can neutralize with bases to form corresponding carboxylic salts and water. For example, when reacting with sodium hydroxide, the hydrogen ion in the carboxyl group binds to the hydroxide ion to form water, and the carboxyl group is converted into the form of sodium carboxylate salt.
    In addition, due to the simultaneous existence of amino and carboxyl groups in the molecule, intramolecular or intermolecular reactions can occur under suitable conditions. For example, autocondensation reactions can be carried out, where amino and carboxyl groups dehydrate and condense to form amide bonds. If it is an intermolecular reaction, a polymer can be formed; if it is an intramolecular reaction, a cyclic structure may be formed.
    Furthermore, the purine ring structure in this compound gives it certain stability and special electron conjugation effects. The conjugate system of purine ring affects the electron cloud distribution of the whole molecule, and also regulates the reactivity of amino and carboxyl groups. The conjugate system can make the molecule resist the attack of external reagents to a certain extent, and also provides a unique reaction check point and reactivity for some specific reactions.
    What are the main applications of 6-aminopyridine-2-carboxylic acid?
    7-Amino-2-naphthalic acid is one of the organic compounds. It has a wide range of uses and has important applications in many fields.
    In the field of dyes, 7-amino-2-naphthalic acid is a key intermediate. With its special chemical structure, it can undergo a series of chemical reactions to synthesize colorful and excellent performance dyes. Such dyes are widely used in textiles, leather and other industries, giving fabrics and leather a brilliant color and good color fastness, so that dyed products can still maintain a bright color after long-term use and washing.
    In the field of medicine, this compound also plays an important role. It can be used as a raw material for the synthesis of various drugs. Due to its specific biological activity and chemical properties, it can participate in the construction of drug molecules. After modification and optimization, it can be made into drugs with specific pharmacological effects, which are used for disease treatment and prevention, and make great contributions to human health.
    Furthermore, in the field of organic synthesis, 7-amino-2-naphthoic acid is used as a basic raw material, providing the possibility for the synthesis of complex organic compounds. Organic chemists use its unique structure and reactivity to synthesize various organic compounds with special functions and structures through ingenious design of reaction routes, promoting the development of organic synthesis chemistry and laying the foundation for the research and development of new materials and other fields. In conclusion, 7-amino-2-naphthoic acid plays an indispensable role in many fields such as dyes, medicine, and organic synthesis due to its unique chemical properties, and is of great significance to industrial production and scientific research.
    What are the synthesis methods of 6-aminopyridine-2-carboxylic acid?
    6-Aminopurine-2-carboxylic acid, namely adenine-2-carboxylic acid, has many synthesis methods, which are described in detail below.
    One is a chemical synthesis method. It can be modified by a suitable purine derivative through a specific chemical reaction. For example, adenine is used as the starting material and under specific conditions, it is carboxylated. In a suitable reaction solvent, a suitable carboxylation reagent is added, such as a system composed of carbon dioxide and a metal catalyst. By adjusting the reaction temperature, pressure and time parameters, carboxyl groups are introduced into the adenine molecule to obtain 6-aminopurine-2-carboxylic acid. The advantage of this method is that it can precisely control the reaction process and the product purity is high; however, its disadvantages are also obvious. The reaction conditions are often harsh, professional equipment and technology are required, and the reagents used may be toxic and dangerous.
    The second is biosynthesis. It can be synthesized by taking advantage of the biocatalytic properties of microorganisms or enzymes. Under specific culture conditions, some microorganisms can synthesize 6-aminopurine-2-carboxylic acids through their own metabolic pathways from simple carbon sources, nitrogen sources, etc. For example, through genetic engineering, microorganisms are modified to make their metabolic pathways biased towards the synthesis of target products. Or enzymes with specific catalytic activities are extracted and synthesized under enzyme catalysis with suitable substrates. This method is green and environmentally friendly, and the reaction conditions are mild; however, the biological system is complex, the fermentation process is not easy to control, and the product separation and purification is more difficult.
    The third is the extraction method of natural products. Some natural biological materials may contain 6-aminopurine-2-carboxylic acids, which can be extracted from these materials by physical and chemical methods. For example, by solvent extraction, select a suitable organic solvent, soak and extract the biological materials containing the target product, and then separate and purify the extract by distillation, crystallization, etc., to obtain 6-aminopurine-2-carboxylic acids. This method has natural raw materials and high product safety; however, the content of target products in natural materials is usually low, the extraction cost is high, and the source of raw materials is limited.
    What is the market price of 6-aminopyridine-2-carboxylic acid?
    In today's market, the price of 6-hydroxydopamine-2-carboxylic acid is particularly difficult to measure. These two are widely used in the field of medicine and chemical industry, but their price is also affected by various factors.
    The output of its origin is one of the main factors. If the origin is vast and the output is stable, the market supply is quite abundant, and the price may be stable and flat; if the origin is narrow, the output will fluctuate from time to time, and the supply will be insufficient, and the price will rise.
    In addition, the raw materials required are also related to the price. If raw materials are easily available and inexpensive, the cost will drop, and the price will follow; if raw materials are rare, difficult to harvest, and the cost will increase greatly, the price will be high.
    Furthermore, the demand of the city affects the price very much. In pharmaceutical research and development, if the demand for the two is urgent, the demand exceeds the supply, and the price will rise; if the demand is weak, the supply exceeds the demand, the price will have a downward trend.
    In addition to the regulation of government and the progress of technology, it is all variable. Strict regulation of government may cause changes in production regulations, affecting supply and demand; new technologies may increase the yield, and the cost will drop, and the price will change accordingly. < Br >
    Therefore, in order to know the market price of 6-hydroxydopamine-2-carboxylic acid, we can obtain its rough outline by looking at the factors of production, supply, raw materials, demand, and politics and technology. The market is unstable, and the price is also unstable. Only by careful investigation can we know the change of its price.
    What are the precautions for storing and transporting 6-aminopyridine-2-carboxylic acids?
    6-Aminopurine-2-carboxylate potassium must pay attention to the following things during storage and transportation:
    First, moisture-proof is essential. This substance is hygroscopic, and in case of humid environment, it is easy to get moisture and agglomerate, resulting in quality damage. Therefore, it should be stored in a dry place, and the packaging must be tight to prevent moisture from invading. If placed in a sealed container, store in a dry warehouse, the ground can be covered with wooden or plastic boards to keep out moisture.
    Second, the temperature should be controlled. High temperature can easily cause its chemical properties to change, or cause decomposition. Generally speaking, it should be stored in a cool place, and the temperature should not exceed 25 ° C. When transporting, it is also necessary to avoid exposure to the sun. If you choose a transportation vehicle with shading facilities, prevent the temperature in the compartment from being too high.
    Third, anti-oxidation cannot be ignored. 6-Aminopurine-2-carboxylate potassium is left in the air for a long time, which is easy to be oxidized by oxygen and affects its performance. Packaging materials can be selected that can isolate oxygen, such as aluminum foil bags. At the same time, an appropriate amount of antioxidants can be added to delay the oxidation process.
    Fourth, avoid contact with foreign matter. This substance should be stored and transported separately from acids, bases and other substances with chemical reactions. Because of its active chemical properties, contact with these substances is prone to chemical reactions, resulting in its failure. For example, it should not be transported in the same car as strong acids and alkalis chemicals, and the warehouse should also be stored in sections.
    Fifth, light loading and light unloading. During loading and unloading, pay attention to operating specifications to avoid violent collisions and drops to prevent packaging damage and affect product quality. Whether it is from the warehouse to the transport vehicle, or to the destination to unload, you need to be careful.