6-Amino-2-phenylpyridine

6-Amino-2-phenylpyridine is one of the organic compounds. It has a wide range of uses and is useful in various fields.
In the field of medicinal chemistry, it is often a key intermediate for the synthesis of drugs. Due to its specific chemical structure, it can interact with targets in organisms and help develop new drugs, such as anti-tumor drugs and antiviral drugs. By modifying and modifying its structure, compounds with specific pharmacological activities can be obtained to meet the needs of treating different diseases.
In the field of materials science, 6-amino-2-phenylpyridine also plays an important role. It can be used to prepare optoelectronic materials, such as organic Light Emitting Diodes (OLEDs). Due to its molecular structural properties, it can emit light under the action of an electric field, and can adjust the luminous color and efficiency by changing its surrounding chemical groups, thereby improving the performance of OLED devices.
In addition, in organic synthetic chemistry, it is an important synthetic building block, which can be connected with other organic molecules through various chemical reactions to build complex organic compound structures. For example, by coupling reactions catalyzed by transition metals and reacting with substrates such as halogenated aromatics, organic molecules with specific functions and structures can be synthesized to expand the variety of organic compounds and meet the needs of different scientific research and industrial applications. Overall, 6-amino-2-phenylpyridine plays a key role in the fields of medicine, materials, and organic synthesis due to its unique chemical structure, promoting the sustainable development and progress of related fields.

6-Amino-2-phenylpyridine is also an organic compound. Its synthesis methods have been various. One method is that 2-bromopyridine and phenylboronic acid can be coupled by Suzuki to obtain 2-phenylpyridine first, and then obtained by nitration and reduction steps. First, 2-phenylpyridine is nitrified at a suitable nitrifying agent, such as a mixed acid of concentrated nitric acid and concentrated sulfuric acid, at a suitable temperature to obtain a nitro-containing derivative, and then a suitable reducing agent, such as iron and hydrochloric acid, is used to reduce the nitro group to an amino group, and then 6-amino-2-phenylpyridine is obtained. < Br >
There is another method, using 2-chloropyridine as the starting material, reacts with phenyl Grignard reagent to generate 2-phenylpyridine, and then nitrates and reduces to obtain the target product. When preparing phenyl Grignard reagent, bromobenzene and magnesium chips can be obtained by reacting in anhydrous ether and other solvents. Then 2-chloropyridine reacts with phenyl Grignard reagent at low temperature to obtain 2-phenylpyridine. Then nitrate and reduce it according to the previous method.
Furthermore, 2-amino-2-phenylpyridine can be condensed with benzaldehyde to form an intermediate, and then 6-amino-2-phenylpyridine can be synthesized through catalytic hydrogenation. 2-Aminopyridine and benzaldehyde are condensed under appropriate acid-base conditions to form an intermediate with carbon-nitrogen double bonds, and then reduced with hydrogen in the presence of a catalyst to obtain the target compound. The catalysts used are often palladium-carbon and the like.
These methods have their own advantages and disadvantages. In the actual synthesis, when the appropriate method is carefully selected according to many factors such as the availability of raw materials, reaction conditions, and high or low yield, 6-amino-2-phenylpyridine can be effectively synthesized.

6-Amino-2-phenylpyridine is a unique presence in organic chemicals. Its physical properties are rich and interesting.
First of all, its appearance, under room temperature and pressure, is mostly white to light yellow crystalline powder state, delicate and uniform, like the fine sand of the years of precipitation, standing in the world, exuding a unique chemical charm.
As for the melting point, it is about 110-114 ℃. Just like the critical point of melting snow in the warm sun in spring, at this temperature, the state of matter changes from solid to melt, the lattice structure gradually disintegrates, and the dance of molecules becomes more active.
Solubility is also an important physical property. It exhibits good solubility in common organic solvents such as ethanol and dichloromethane. Ethanol, like a warm embrace, opens its own molecular gap, and readily accepts 6-amino-2-phenylpyridine molecules. The two blend seamlessly, like old friends reunite. In water, the solubility is relatively limited, and the polarity of water is slightly less compatible with the partial structure of the substance, making it difficult to form a uniform state in water.
Re-discussion of density, although there is no exact and widely circulated accurate value, but according to its molecular structure and analogy with similar substances, the density should be similar to that of common organic compounds. Its density is related to many practical application scenarios, and it is of important consideration in the ratio of materials in the synthesis process and the design of chemical production equipment.
In addition, the stability of this substance is also worthy of attention. Under conventional environmental conditions, it is still stable. However, in case of extreme chemical environments such as strong oxidants and strong acids and alkalis, the molecular structure may be changed due to impact. This stability is just like human nature. It can be safe in a peaceful environment, but it may be difficult to maintain its own state in the event of strong winds and rains.
The physical properties of 6-amino-2-phenylpyridine are like a fine painting, each stroke depicts its unique pose in the chemical world, laying an important foundation for its application in many fields such as organic synthesis and drug development.

6-Amino-2-phenylpyridine is one of the organic compounds. Its chemical properties are unique and interesting.
This compound is basic, because its amino group can bind protons, in an acidic environment, it can react with acids to form corresponding salts. This property allows it to act as a neutralizing agent or participate in ion exchange reactions in some acid-base related chemical reactions.
Furthermore, the phenyl ring structure of 6-amino-2-phenylpyridine gives it certain stability and aromaticity. The phenyl ring can participate in many reactions such as electrophilic substitution reactions. For example, under appropriate conditions, halogenation reactions can occur, and halogen atoms will replace hydrogen atoms on the benzene ring; nitration reactions can also be carried out to introduce nitro groups; sulfonation reactions can also occur, so that sulfonic acid groups are connected to the benzene ring.
Its amino groups can also participate in many reactions. For example, acylation reactions can occur with acyl halides or acid anhydrides, and hydrogen atoms on the amino group are replaced by acyl groups to form amide compounds. This reaction is often used in organic synthesis to construct compounds containing amide bonds, which are crucial in many drugs and bioactive molecules.
At the same time, 6-amino-2-phenylpyridine may also act as a ligand to coordinate with metal ions. The nitrogen atoms on the amino and pyridine rings can provide lone pairs of electrons to metal ions to form stable complexes. Such complexes may have unique catalytic properties in the field of catalysis and can catalyze the progress of some organic reactions.
In summary, 6-amino-2-phenylpyridine exhibits rich and diverse chemical properties due to its amino and phenyl ring structures, and has potential applications in many fields such as organic synthesis and catalysis.

The price of 6-amino-2-phenylpyridine in the market often varies depending on the purity of the product, the situation of supply, and the amount of demand. According to the ancient saying in "Tiangong Kaiwu", although the price of this product is not detailed, it is based on common sense and follows the rules of commerce.
If its product is extremely pure, and there are many people in the market who want it, and there are few people who supply it, the price will be high. Or up to thousands of gold, this is the domain of high price. Cover because of its purity, it is widely used, and pharmaceuticals, research and development of new materials are all needed, and the price will rise from those who seek it. < Br >
If the product is slightly inferior, and the market supply is sufficient, and the seeker is not extremely urgent, the price should be reduced. Or to the spectrum of hundreds of gold, this is the state of the medium price. Although the quality is not high, it is still sufficient for ordinary work, study and research, so the price is not too high.
If the market is full of this product, and there are few seekers, the price will be low. Or only a few dozen gold ears, this is a low price. Due to oversupply, merchants want to sell quickly, so they have to reduce the price in order to get rid of it.
And its price also changes with the market. The demand is urgent, although the quality is not good, the price is also high; the demand is slow, even if the pure product, the price is difficult to be high. Therefore, the price of 6-amino-2-phenylpyridine is roughly in the range of tens of gold to thousands of gold, and the actual price depends on the actual situation of the market.