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What is the chemical structure of 7-Dihydro-5H-pyrrolo [3,4-b] pyridine hydrochloride?
The chemical structure of 6,7-dihydro-5H-pyrrolido [3,4-b] pyridine hydrochloride is quite interesting. This compound is formed by the combination of pyrrole and pyridine to form a unique ring system. The pyrrolido [3,4-b] pyridine part is fused by the five-membered ring of pyrrole and the six-membered ring of pyridine. In the 6,7-dihydro state, that is, the double bond hydrogenation at the 6,7 position, it is in a saturated state. The hydrochloride salt is due to the basic nitrogen atom of the compound, which can react with hydrochloric acid to form salts. This structure makes the substance have the characteristics of both pyrrole and pyridine, and its physical and chemical properties are also different from those of the parent base due to its salt formation. Its unique ring structure, or endows it with specific biological activities, is of great research value in the fields of medicinal chemistry and organic synthetic chemistry. Its unique structure is one of the examples of structural diversity of organic compounds, paving a new way for many chemical research and applications.
What are the main uses of 7-Dihydro-5H-pyrrolo [3,4-b] pyridine hydrochloride?
6,7-Dihydro-5H-pyrrolido [3,4-b] pyridine hydrochloride is widely used in the field of pharmaceutical and chemical industry.
It is a key intermediate in pharmaceutical chemistry. The synthesis of many biologically active compounds is often based on this. Due to its unique structure, it can provide a core framework for the construction of new drug molecules and help develop new drugs for the treatment of various diseases, such as neurological diseases, cardiovascular diseases, etc. As the ancient saying goes, this is the cornerstone of new drug creation. If you build a giant building, you must first build a foundation. Its contribution to the research and development of new drugs is as indispensable as a pillar in a vast building. < Br >
In organic synthesis chemistry, it is also a commonly used reagent. Chemists use its unique reactivity to perform various organic reactions, such as nucleophilic substitution, cyclization, etc. From this, many complex organic compounds can be derived, providing raw materials for materials science, total synthesis of natural products and other fields. Just like skilled craftsmen use it as a material to carve thousands of exquisite tools and enrich the treasure house of organic synthesis.
In addition, it also plays an important role in the study of biological activity. Because it may interact with specific targets in organisms, researchers use it to explore the physiological and pathological mechanisms in organisms. Like unlocking the key, it explores the door to the mystery of life and provides key clues for revealing the principles of life processes and disease occurrence and development.
What is the synthesis method of 7-Dihydro-5H-pyrrolo [3,4-b] pyridine hydrochloride?
To prepare 6% 2C7-dihydro-5H-pyrrolido% 5B3% 2C4-b% 5D pyridine hydrochloride, the method is as follows:
First take a suitable starting material, which should contain the necessary groups to construct the core structure of the target molecule. Or choose a fragment of pyrrole and pyridine structure with reactive functional groups, so that the desired fused structure can be constructed through subsequent reactions.
Usually take the classical reaction of chemical synthesis as the route. For example, the nucleophilic substitution reaction is used to react the nitrogen-containing nucleophile with a halogenated hydrocarbon or sulfonate with suitable leaving groups to connect the pyridine and pyrrole fragments. In the meantime, the control of the reaction conditions is the key, such as temperature, solvent, type and dosage of alkali, etc., all need to be carefully regulated. If the temperature is too high, or side reactions occur frequently, the product is impure; if the temperature is too low, the reaction rate will be slow and take too long.
Wait until the key skeleton is initially formed, and then perform the hydrogenation reaction to obtain the dihydrogen structure. At this time, suitable catalysts, such as palladium carbon, Raney nickel, etc., should be selected, and the catalyst dosage should be rationally allocated according to the reaction scale and demand. The hydrogen pressure also needs to be considered, and the pressure should be moderate to ensure the smooth progress of the hydrogenation reaction, and the target 6% 2C7-dihydrogen structure can be obtained.
Finally, the resulting 6% 2C7-dihydro-5H-pyrrole% 5B3% 2C4-b% 5D pyridine interacts with hydrogen chloride gas or hydrochloric acid solution to form its hydrochloride salt. This step requires attention to the stoichiometry of the reaction, so that the acid and base can form just a salt, and the reaction environment should be dry to prevent side reactions such as product hydrolysis, resulting in a pure 6% 2C7-dihydro-5H-pyrrole% 5B3% 2C4-b% 5D pyridine hydrochloride.
What are the physical and chemical properties of 7-Dihydro-5H-pyrrolo [3,4-b] pyridine hydrochloride?
6,7-Dihydro-5H-pyrrolido [3,4-b] pyridine hydrochloride, this substance has different properties and has several physical and chemical properties.
Looking at its physical properties, it is in the shape of powder under normal conditions. Its color is white as snow, and its texture is fine as dust. It is placed in the palm of the hand, like a light feather. It dissolves well in water, just like salt melts in water, invisible and invisible, quietly merging into the liquid phase. This is due to the strong attractive force between some groups in the molecular structure and water molecules.
As for chemical properties, this compound is weakly alkaline. The nitrogen atom in its structure is like a humble gentleman, slightly accepting the energy of protons. In an acidic environment, it can happily embrace protons and form a stable cationic structure, which is the fundamental reason for its salt formation with hydrochloric acid. And its chemical stability is also considerable. Under normal temperatures and environments, it can maintain its own structure intact for a long time, like a rock. When encountering strong acids and alkalis, its structure may change, like a weak flower being attacked by wind and rain, some chemical bonds may break and recombine. In the field of organic synthesis, 6,7-dihydro-5H-pyrrolido [3,4-b] pyridine hydrochloride is often a key raw material. With its unique structure, it can participate in multiple chemical reactions, such as nucleophilic substitution, addition, etc. It is like the cornerstone of a delicate building, and plays an indispensable role in the grand project of building complex organic molecules.
What is the price range of 7-Dihydro-5H-pyrrolo [3,4-b] pyridine hydrochloride in the market?
I haven't heard of "6% 2C7 - Dihydro - 5H - pyrrolo% 5B3% 2C4 - b% 5Dpyridine + hydrochloride" in the exact price range on the market. This is a fine chemical product, and its price varies depending on quality, purity, supply and purchase quantity. If you want, you should consult chemical raw material suppliers, chemical reagent houses, or explore chemical product trading platforms.
The price of high purity is high, because the purification technique is complicated and expensive. The purchase quantity is also a major factor. If the batch is large, the unit price may be discounted. However, I have not seen its market situation in person, so it is difficult to determine the exact price. It may be a few yuan to tens of yuan per gram, or due to special needs and quality, the price is even higher. If you want to know the details, you need to visit the business or platform in person, ask the price and inquire about the situation, and get a close price range.