5h Pyrazolo 4 3 C Pyridine 5 Carboxylic Acid 1 4 6 7 Tetrahydro 1 1 Dimethylethyl Ester
pyridine pyrrole pyrazine piperidine piperazine

5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester

    Specifications

    HS Code

    155630

    Chemical Formula C12H18N2O2
    Molar Mass 222.28 g/mol
    Appearance Solid (predicted)
    Solubility Insoluble in water (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading 5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 5H-pyrazolo [4,3-c] pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester?
    This is a structural problem of a complex organic compound. According to the information given, the name of this compound is 5H-pyridino [4,3-c] pyridino-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester.
    To clarify its chemical structure, first look at the main frame. "Pyridino [4,3-c] pyridine" shows that it is formed by fusing two pyridine rings in the order of [4,3-c]. Pyridine rings are nitrogen-containing six-membered heterocycles with conjugated systems.
    "5-carboxylic acid", which shows that the carboxyl group (-COOH) is attached at the 5th position of the fused ring. "1,4,6,7-tetrahydro", which means that the carbon-carbon double bond at the four positions of 1, 4, 6, and 7 is hydrosaturated, and the unsaturated pyridine ring is partially converted to a structure similar to the piperidine ring.
    "1,1-dimethylethyl ester", indicating that the carboxyl group (-COOH) forms an ester bond (-COO -) with 1,1-dimethylethyl group (ie, tert-butyl-C (CH 🥰)).
    In summary, the structure of this compound is based on pyridino [4,3-c] pyridine as the basic skeleton, the 5-position carboxyl group is connected with tert-butyl to form an ester, and the 1, 4, 6, and 7 positions are occupied by saturated hydrogen atoms. In this way, its complete chemical structure can be obtained.
    What are the main uses of 5H-pyrazolo [4,3-c] pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester?
    5H-pyrrole [4,3-c] pyrrole-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethyl ethyl ester, this substance is widely used. In the field of medicinal chemistry, it may be a key intermediate for the synthesis of specific drugs. Due to the unique chemical structure of this compound, it can be precisely spliced with other molecules by organic synthesis to construct new drug molecules with specific biological activities, which is of great significance for the development of specific drugs for specific diseases.
    In the field of materials science, it may be used as a raw material for the preparation of special functional materials. For example, by appropriate chemical modification and processing, the material has unique photoelectric properties, which is expected to be applied to organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices to improve the performance and efficiency of the device.
    In the field of organic synthetic chemistry, it can serve as a key building block, participating in the construction of complex organic molecules with its structural characteristics. Chemists can use this to design and synthesize organic compounds with novel structures and specific functions, providing new directions and possibilities for the development of organic synthetic chemistry.
    In biochemical research, this substance may be used as a biological probe to label and track specific molecules or biological processes in organisms. Due to its specific structure, it can specifically bind to certain targets in living organisms, which helps researchers gain a deeper understanding of the physiological and pathological mechanisms in living organisms.
    What are the synthesis methods of 5H-pyrazolo [4,3-c] pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester?
    To prepare 5H-pyrrolio [4,3-c] pyrrole-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester, there are three methods.
    One is to start with a pyrrole derivative and convert it in multiple steps. The necessary groups are introduced by substitution reaction between pyrrole and a specific halogen under alkali catalysis. This step requires controlling the reaction temperature and time to avoid side reactions. The obtained product is oxidized, modified with a specific position functional group, and then reacted with a carboxyl-containing precursor under suitable conditions to construct the carboxylic acid part of the target structure. Finally, through esterification reaction, 1,1-dimethylethyl ester group is introduced.
    Second, starting from a simple cyclic compound. First, the basic skeleton of pyrrole-pyrrole is constructed by cyclization reaction. This process requires the selection of suitable catalysts and reaction solvents to promote the efficient cyclization. Then the skeleton is hydrogenated to obtain 1,4,6,7-tetrahydrogen products. Then carboxylation reagents are used to introduce carboxyl groups at appropriate positions, and finally esterification is used to obtain the target product.
    Third, a convergence synthesis strategy is adopted. Pyrrole-pyrrole skeleton fragments and carboxyl-containing and 1,1-dimethyl ethyl ester fragments are synthesized respectively. The reaction routes of each synthetic fragment need to be precisely designed to ensure the activity and selectivity of functional groups. Then the two fragments were connected by a coupling reaction to obtain the target 5H-pyrrolio [4,3-c] pyrrole-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethyl ethyl ester. Each method has advantages and disadvantages, and the actual synthesis needs to be selected according to factors such as raw material availability, cost and reaction conditions.
    What are the physicochemical properties of 5H-pyrazolo [4,3-c] pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester?
    5H-pyridino [4,3-c] pyridino-5-carboxylic acid, 1,4,6,7-tetranitrogen, 1,1-dimethyl ethyl ester, this is an organic compound. Its physicochemical properties are quite important, related to its performance in various chemical processes and practical applications.
    When it comes to physical properties, under normal circumstances, this compound may be solid, and the specific appearance may vary depending on the purity and crystallization conditions, or it may be white to slightly yellow powder or crystal. Melting point is of great significance for its identification and purity determination. After precise determination, a specific melting point value can be obtained. This value is affected by intermolecular forces and crystal structure. The boiling point is also a key parameter, reflecting the temperature conditions of the compound during the gas phase transition, revealing the strength of intermolecular interactions.
    In terms of solubility, in organic solvents, such as common ethanol, dichloromethane, N, N-dimethylformamide (DMF), or show some solubility, but in water, solubility or poor. This property is closely related to the molecular structure of the compound, and the functional groups such as pyridine rings and ester groups it contains affect the interaction with different solvent molecules. Pyridine rings have certain hydrophobicity, and ester groups also affect molecular polarity, resulting in different solubility in polar and non-polar solvents.
    Chemically, the 5-carboxylic acid site is acidic and can neutralize with bases to form corresponding carboxylic salts. This reaction can be used in organic synthesis to adjust the solubility of compounds and participate in salt-forming modification to improve pharmacokinetic properties. The structure of 1,4,6,7-tetranitrogen endows compounds with certain alkalinity, which can react with acids to form salts, and because of the presence of lone pairs of electrons in nitrogen atoms, it is easy to participate in nucleophilic reactions. As a nucleophilic reagent, it reacts with electrophilic reagents to form new chemical bonds for the synthesis of more complex organic molecules. 1,1-Dimethyl ethyl ester is relatively stable, but under certain conditions, such as strong acid, strong base or high temperature environment, ester bonds can undergo hydrolysis to form carboxylic acids and alcohols, which cannot be ignored in organic synthesis and drug metabolism.
    What is the price range of 5H-pyrazolo [4,3-c] pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester in the market?
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