5h 1 Benzopyrano 2 3 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

5H-[1]-Benzopyrano[2,3-B]Pyridine

    Specifications

    HS Code

    456103

    Molecular Formula C14H9NO2
    Molar Mass 223.23 g/mol
    Appearance Typically a solid (physical appearance can vary)
    Melting Point Data may vary depending on purity and form
    Boiling Point Data may vary depending on purity and form
    Solubility Solubility characteristics would depend on solvents; may be sparingly soluble in water
    Density Data may vary; density related to its physical state and packing
    Chemical Stability Stability can be affected by light, heat, and reactive substances
    Pka Relevant acid - base properties would have associated pKa values (data may vary)
    Uv Vis Absorption Exhibits characteristic absorption in the UV - Vis spectrum due to conjugated systems

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    Frequently Asked Questions

    As a leading 5H-[1]-Benzopyrano[2,3-B]Pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 5H- [1] benzopyrano [2,3-B] pyridine?
    5H - [1] benzothiopheno [2,3 - B] thiophene, the chemical properties of this substance are as follows:
    It is aromatic, because its structure contains multiple conjugated ring systems, satisfies the Shocker rule, has certain stability, is not easy to undergo addition reactions like olefins, and is more inclined to electrophilic substitution reactions.
    The electrophilic substitution reaction activity is quite high, because its electron cloud density on the ring is relatively high. Taking the benzene ring as a reference, the electron cloud distribution of the thiophene ring makes it more vulnerable to electrophilic attack. In many electrophilic substitution reactions, the reaction check point is mostly preferred to the area with higher electron cloud density on the thiophene-thiophene ring. For example, in halogenation reactions, halogen atoms are prone to replace hydrogen atoms at specific positions.
    has good thermal stability and can withstand a certain high temperature without easily decomposing the structure. This is due to the delocalized π bond formed by its conjugate structure, which enhances the stability of the molecule.
    In terms of redox properties, due to the sulfur-containing atoms and the outer electronic structure of sulfur atoms, they can participate in redox reactions under specific conditions. Under the action of oxidizing agents, the valence of sulfur atoms can increase, and oxidation reactions can occur; in specific reduction environments, corresponding reduction reactions can also occur. In terms of solubility, the substance has a certain solubility in organic solvents, such as common non-polar or weakly polar organic solvents such as dichloromethane and chloroform. Due to the similarity between the molecular structure and these solvents, the solubility in water is minimal, due to the large difference between the non-polar characteristics of the molecules and the polarity of water.
    What are the common uses of 5H- [1] benzopyrano [2,3-B] pyridine?
    5H- [1] benzopyrano [2,3-B] pyridine has many common uses. This compound is valuable in the field of medicine and is often used as a key intermediate in drug synthesis. Because it has a specific chemical structure and activity, it can participate in the construction process of various complex drug molecules. By chemically modifying and derivatizing it, drugs with different pharmacological activities can be developed, such as drugs for the treatment of cardiovascular diseases or drugs with anti-tumor activity.
    In the field of materials science, 5H- [1] benzopyrano [2,3-B] pyridine is also used. Due to its unique optical and electrical properties, it can be used as a component of organic optoelectronic materials. For example, in organic Light Emitting Diodes (OLEDs), it may serve as a light-emitting layer material or auxiliary material to help improve the luminous efficiency and stability of the device, thereby optimizing the display effect.
    In addition, in the field of organic synthetic chemistry, it is a characteristic structural unit, often used by chemists to design and synthesize novel organic compounds to explore new reaction paths and chemical properties. With its unique molecular structure, it can undergo specific chemical reactions with many reagents, providing the possibility for the synthesis of organic molecules with special functions and structures, thereby promoting the development and progress of organic chemistry.
    What are the synthesis methods of 5H- [1] benzopyrano [2,3-B] pyridine
    There are many methods for the synthesis of 5H - [1] indylpyrrolido [2,3 - B] pyridine, each with its own advantages and disadvantages. The following is a detailed description of Jun:
    First, this structure can be obtained by cyclization reaction with o-haloaniline compounds and pyridine derivatives containing alkynyl groups as raw materials under the catalysis of transition metals. This method has mild conditions and good selectivity. However, the preparation of raw materials is slightly complicated, and multiple steps are required to obtain high-purity substrates. The cost of transition metal catalysts is high, and the requirements for reaction equipment and operation are also strict. A little carelessness affects the yield and purity.
    Second, the skeleton is constructed by nucleophilic substitution reaction within the molecule. Select an appropriate precursor compound containing nitrogen and leaving groups such as halogenated or sulfonate. Under the action of alkali, the intracellular nucleophilic reagents attack the leaving group and cyclize to form the target product. This approach is simple in steps and has high atomic economy. However, the design and preparation of the reaction substrate need to be exquisitely conceived, and the control requirements for the reaction conditions are strict. Otherwise, side reactions will easily occur and the yield and purity of the product will be reduced.
    Third, a multi-component reaction strategy is adopted. With simple raw materials such as aldehyde, amine, and alkyne, in the presence of specific catalysts or accelerators, it is synthesized by a multi-step series reaction one-pot method. This method is easy to operate, with a wide range of raw material sources, and can effectively build a product library with complex and diverse structures. However, the reaction mechanism is complex, and the proportion of each component, reaction sequence and conditions need to be finely regulated, otherwise it is difficult to obtain the ideal product.
    Fourth, the cyclization and condensation reaction between heterocycles and heterocycles is used. For example, specific pyridine derivatives and indole derivatives undergo condensation cyclization under acid or base catalysis. This method can directly construct the target fused ring system by using the existing heterocyclic structure. The operation is relatively convenient, but the substrate structure requires special requirements, and the catalyst selection and dosage need to be precisely optimized to improve the reaction activity and selectivity.
    What is the market outlook for 5H- [1] benzopyrano [2,3-B] pyridine?
    Wuguanfu 5H - [1] The merging of bees to the nest [2,3 - B] to its market prospects is related to the interests of merchants and the prosperity of the industry.
    In today's world, business is prosperous, and all kinds of new things are competing. 5H - [1] The merging of bees to the nest [2,3 - B] is unique. From the perspective of its function, it may be beneficial to the mulberry. Ancient farmers relied on bees to pollinate, so that the crops were prosperous and the fruits were fruitful. If this bee makes good use of it, it can increase agricultural output. In the realm of the surrounding neighbors, the business of farming and mulberry is still prosperous. If it is supplemented by 5H - [1] bees and nests [2, 3 - B], it will be able to plant Jiamu widely and harvest five grains.
    In the road of medicine, it may also be possible. Ancient physicians often sought natural things to cure diseases. The products of bees, such as honey, wax, poison, etc., are all included in the pharmacopoeia. The products produced by this bee may have different effects, and they can be used by the doctor to cure the diseases of all people.
    As for the cities, everyone is fond of novelties. 5H - [1] Bees and nests [2,3 - B] If they can be made into treasures, or they can be liked by Yashi; if they can be brewed into beautiful brews, they will attract drinkers to compete. And today's people, who love the way of health, the various products of bees, or can be the choice of health care, will have a wide market.
    However, if you want to expand its market, there are also difficulties. First, people always have doubts about new things. It must be widely publicized and made known to everyone. Second, keep its reproduction and protect its ecology, so that it can have a long history. If you are good at managing all things, the market prospect of 5H - [1] bee merging to the nest [2, 3 - B] will be like the rising sun, and the brilliance will gradually rise, which will generate wealth for the country and benefit the people.
    What are the applications of 5H- [1] benzopyrano [2,3-B] pyridine in the field of medicine?
    5H - [1] Ligopyrido [2,3 - B] pyridine, this compound has many applications in the field of medicine.
    In terms of antibacterial drugs, its structural properties endow it with potential antibacterial activity. Some compounds containing similar structures can inhibit the cell wall synthesis or protein synthesis process of specific bacteria, thus achieving the purpose of antibacterial. For example, some studies have shown that after modifying and modifying the structure, the obtained derivatives can effectively inhibit the growth and reproduction of Gram-positive and Gram-negative bacteria, and are expected to be developed into new antibacterial drugs to deal with the increasingly serious problem of bacterial drug resistance.
    In the field of neurological drug development, 5H - [1] Ligopyridine [2,3 - B] pyridine also shows certain potential. Its structure has certain affinity with some neurotransmitter receptors, which can regulate the transmission process of neurotransmitters. For example, by binding to specific neuroreceptors, it affects the conduction of neural signals, which in turn regulates the function of the nervous system. It may be used to treat neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, and improve cognitive function and motor symptoms in patients.
    In addition, in the field of cardiovascular drugs, relevant studies have found that these compounds can affect the ion channels in the cardiovascular system. It can regulate the ion flow of cardiomyocytes and stabilize the membrane potential of cardiomyocytes, thus playing a therapeutic role in cardiovascular diseases such as arrhythmias. At the same time, it may also affect the contraction and relaxation of vascular smooth muscles, regulate blood pressure, and provide new drug development directions for the treatment of cardiovascular diseases.