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What are the main uses of 5- (trifluoromethyl) pyridine-2-thiol?
The main use of triethylamine dichloride is an important part of the chemical industry.
dichloride, its activity, in the way of synthesis, is often filled with chlorination. In the case of alcohol compounds, dichloride can be reversed, and it can replace the alcoholization phase. This reaction is reliable, and the yield is good. It is a common means to build carbon in the synthesis. In addition, the compound of carboxylic acid, dichloride can be made to reduce acetyl chloride, which is an important reaction in the synthesis. It can be used in one step, such as acetylation and other multi-reaction compounds, such as esters and amides.
Triethylamine, as a chemical compound, also plays an indispensable role in chemical synthesis. First, in many reactions, it can be used as a catalytic catalyst. For example, in esterification reactions, triethylamine can promote the inverse equilibrium to shift in the direction of ester generation, improving the inverse efficiency. Second, in some reactions involving nuclear substitution, triethylamine can react to the generated acid, avoid the inhibitory effect of acid reactions, and ensure the effectiveness of the reaction. In addition, triethylamine can be used for the acidity of the reaction system due to its properties, in order to meet the needs of specific reactions.
Therefore, dichlorotriethylamine plays an important role in the synthesis, chemical production, and other fields of chemical production, and by virtue of its respective chemical properties, it helps to promote the development of chemical production.
What are the synthesis methods of 5- (trifluoromethyl) pyridine-2-thiol?
To prepare triethylalkyl-2-boronic acid, the following methods can be used.
First, triethylalkyl boron is reacted with peroxide. In this case, triethylalkyl boron encounters suitable peroxides, such as hydrogen peroxide, under suitable conditions, boron atoms can be oxidized, and then hydroxyl groups can be introduced, and then the target product can be converted through a series of conversions. This process requires temperature control, reaction time and ratio of reactants. If the temperature is too high, the product may decompose, and if the ratio is not correct, the yield will be affected.
Second, through the Grignard reagent method. Grignard reagents such as triethylalkyl magnesium halide are first prepared, and then reacted with borate esters. Grignard reagents are highly active and meet borate esters. Alkyl groups can be transferred to boron atoms to achieve the synthesis of the target product. However, Grignard's reagent has strict requirements on the reaction environment and needs to be anhydrous and oxygen-free. Because water and oxygen will cause it to decompose, the reaction fails.
Third, the coupling reaction of metal-organic compounds with boron-containing compounds is used. For example, under the catalysis of some transition metals, triethylalkyl-containing metal-organic compounds are coupled with boron-containing halides or boric acid derivatives. This method has good selectivity and high yield. However, the cost of transition metal catalysts is high, and the reaction conditions need to be precisely regulated, such as catalyst dosage, reaction solvent and temperature, etc., in order to achieve the desired effect.
All these methods have advantages and disadvantages. In the actual synthesis, it is necessary to make a careful choice according to the availability of raw materials, cost considerations, product purity requirements and other factors, and strive to synthesize triethyl alkyl-2-boronic acid efficiently, economically and environmentally friendly.
What are the physical properties of 5- (trifluoromethyl) pyridine-2-thiol?
The physical properties of (trimethylmethyl) alkane-2-gypsum are as follows:
Its color is often white, or it is gray, gray, and other colors. Its shape is multi-dimensional, or it has a high quality. It has a slippery feeling, and its hardness is low. With nails, it can leave marks. Mohs hardness is 2, and it is often used.
Its specific gravity is also not very high, about 2.3. It feels good when placed in the hand. Gypsum has good insulation. It is not easy to burn on fire and can be guaranteed for a period of time. And it has a certain degree of water absorption, if placed in the damp, it can absorb water vapor, and its weight also increases.
Furthermore, gypsum has good plasticity, and the amount of water added can be mixed to form a paste. The paste can be molded into various shapes as needed. When it dries, it can be hardened and formed, and it can maintain the molded shape. And gypsum has fire resistance. In case of high temperature, it may lose part of the crystal water, but its basic shape can still be maintained to a certain extent, and it will not be fusible. This property makes it useful in many fields such as construction.
What are the precautions for 5- (trifluoromethyl) pyridine-2-thiol during storage and transportation?
Triethylamine diatomaceous earth needs to be paid attention to in the process of storage and production.
Triethylamine has a certain degree of corrosion, and the material requirements for its storage container are very high. It is necessary to use materials that can resist its corrosion, such as specific alloys or containers with anti-corrosion materials, to prevent the leakage of triethylamine caused by the container. And the dense storage, the less the connection of the air, because of the biochemical reaction of some components in the air, and the change of its own nature.
In terms of the storage environment, it is necessary to maintain the dryness and dryness. High or tidal conditions may affect the characterization of triethylamine, and even lead to dangerous reactions.
Diatomaceous earth is stable, but the storage should also pay attention to moisture prevention. Moisture is easy to make it absorb moisture, reduce its adsorption performance, and affect its use efficiency. And the source of ignition and oxidation, because its main component contains silicon, it is not flammable, but under special conditions or oxidation, it will cause a reaction.
In the process, triethylamine is determined according to the phase of the dangerous chemical product. It is necessary to have phase protection, such as fire protection, explosion protection, anti-leakage, etc., familiar with the dangerous characteristics of triethylamine and emergency treatment measures.
In addition, triethylamine diatomaceous soil exists and does not exist, and each has its own needs, and it must be operated in accordance with each other to ensure safety.
What is the approximate market price of 5- (trifluoromethyl) pyridine-2-thiol?
"Tiangong, (Sanxiang methyl) to its - 2 - gypsum in the market, fixed, because of the land. However, according to normal circumstances, each catty can be used in the text to ten text.
The use of gypsum by the husband is good, and it is beneficial to the work. Workers use the mold, and take it to shape; those who apply it to the field can be used to make crops. Its needs are both good, and the market is also good for supply and demand.
If the year is full of time, a lot of work is done, and the demand for gypsum is ardent, or a little bit; if it is a famine year, the work is not done, the work is not done, and the demand is not enough, and the demand is also falling. And the proximity of the land, the convenience of the time, all of them are made of grid.
The nearby land, the province is saved and flat; the lack of money is increased, and the use is high. In addition, the amount of rainwater is different, and it also affects the excavation of gypsum. Therefore, the city is uniform, but it is roughly 10 texts per catty to ten texts for consideration.