5-(Tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid

This is a structural study of 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydrothiazolo [5,4-c] pyridine-2-carboxylic acid. This compound contains tert-butoxycarbonyl, which is often used as an amino protecting group in organic synthesis due to its steric resistance and stability. The thiazolopyridine ring is its core, which is formed by fusing the thiazole ring with the pyridine ring, giving it unique chemical and biological activity. The tetrahydro structure gives the ring a specific conformation and flexibility.
Furthermore, the 2-position is connected with a carboxyl group, which is acidic and can participate in a variety of chemical reactions, such as salt formation, esterification, etc. Overall, the structural characteristics of 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydrothiazolo [5,4-c] pyridine-2-carboxylic acid make it potentially valuable in the fields of medicinal chemistry and organic synthetic chemistry, or can be used as a lead compound for the development of new drugs, or as an important intermediate in organic synthesis.

5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydrothiazolo [5,4-c] pyridine-2-carboxylic acid, this compound has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique molecular structure, it can be chemically modified to derive a variety of biologically active compounds, which can be used in drug development, such as the creation of new therapeutic drugs for specific disease targets.
In the field of organic synthesis, it is an important cornerstone for the construction of complex heterocyclic structures. Organic synthesizers can use it to perform various reactions, such as nucleophilic substitution, cyclization, etc., to construct more complex and delicate organic molecules and expand the variety and structure of organic compounds. < Br >
In the field of materials science, there may also be potential applications. With specific design and modification, materials may be endowed with special properties, such as optical and electrical properties, providing a possible path for the development of new functional materials. In short, this compound has important value in many scientific research and application fields, providing key assistance for the development of related fields.

To prepare 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydrothiazolo [5,4-c] pyridine-2-carboxylic acid, the following method can be followed.
First take appropriate starting materials, such as the corresponding pyridine and thiazole structure precursors. Under mild reaction conditions, in a suitable solvent system, the pyridine ring is connected to the thiazole ring, and appropriate protective groups are introduced at specific positions to facilitate subsequent reactions. For example, pyridine can be combined with thiazole fragments by nucleophilic substitution or condensation reactions. During this process, attention should be paid to the selectivity of the reaction check point. This purpose can be achieved by controlling the reaction temperature, the proportion of reactants and the type of catalyst.
After the initial formation of the ring system, the protection group of tert-butoxycarbonyl (Boc) is introduced. Usually di-tert-butyl dicarbonate (Boc -2 O) is used as a protective reagent. In the presence of organic bases such as triethylamine or N, N-diisopropylethylamine, it is reacted in organic solvents such as dichloromethane or tetrahydrofuran. This reaction condition should be mild to avoid damage to the formed ring system.
As for the construction of carboxyl groups, it can be achieved at a suitable stage by oxidation, hydrolysis or other functional group conversion reactions of the corresponding precursors. For example, if the starting material contains oxidizable functional groups, such as aldehyde groups or alcohol groups, an appropriate oxidizing agent can be selected to convert them to carboxyl groups under suitable reaction conditions. Or through the hydrolysis of ester groups, under basic conditions, the corresponding ester precursors are treated with sodium hydroxide or potassium hydroxide aqueous solutions to obtain the target carboxyl group.
During the entire synthesis process, each step of the reaction requires analysis by thin layer chromatography (TLC), nuclear magnetic resonance (NMR) or mass spectrometry (MS) to monitor the reaction process, confirm the structure and purity of the product, and ensure the smooth progress of the synthesis route. Finally, 5 - (tert-butoxycarbonyl) -4,5,6,7 - tetrahydrothiazolo [5,4 - c] pyridine-2 - carboxylic acid.

5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydrothiazolo [5,4-c] pyridine-2-carboxylic acid, this is an organic compound. Its physicochemical properties are particularly important, related to its performance in various chemical reactions and practical applications.
First talk about the appearance and properties. This compound is often in a white to white solid state, with a fine texture. It looks like fresh snow in winter, pure and simple. This form is conducive to its storage and transportation, and is easy to disperse and participate in reactions in many reaction systems.
In terms of melting point, its melting point is in a specific temperature range, which is like the "personality label" of the compound. Accurate melting point data can help identify the purity of the compound. If the purity is extremely high, the melting point is sharp and stable; if it contains impurities, the melting point may be offset and the melting range is widened.
Solubility is also a key property. In common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., this compound exhibits a certain solubility. In dichloromethane, it is like ice and snow meeting warm sun, slowly melting in it to form a uniform and clear solution, which makes it fully in contact with other reactants in the reaction system using dichloromethane as the solvent, promoting the efficient progress of the reaction. In water, its solubility is very small, like a lotus leaf that repels water, and it is difficult to blend with water. This is due to the role of hydrophobic groups in the molecular structure of the compound.
In terms of stability, under conventional environmental conditions, it is relatively stable, just like a calm old man, calm. However, in case of extreme conditions such as strong acids, strong bases or high temperatures, its structure may change. In case of strong acids, tert-butoxycarbonyl may fall off, triggering a rearrangement of the molecular structure, which in turn changes its chemical properties and functions.
The physicochemical properties of this compound may vary due to the electronic and spatial effects of the substituents. Different substituents add different "wings" to compounds, affecting their intermolecular forces, thereby changing their melting point, solubility and other properties. Its physicochemical properties are of great significance in organic synthesis, drug development and other fields, providing key basis and guidance for exploring new reaction paths and designing efficient drug delivery systems.

Today I have a question, what is the market price of 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydrothiazolo [5,4-c] pyridine-2-carboxylic acid. This is a fine chemical, and its price often varies depending on quality, supply, and purchase quantity.
In the past, in the world of "Tiangong Kaiwu", there were no such fine chemicals. Today's chemical industry is prosperous, and this compound has a wide range of uses. It may be used in pharmaceutical research and development, and is a key raw material for the creation of new pharmaceuticals. If it is of high quality and purchased in small quantities by scientific research institutions, the price per gram may reach several hundred yuan.
If it is purchased in bulk industry, the unit price may be greatly reduced due to the scale effect. In the chemical raw material trading market, its price is also influenced by supply and demand. If supply exceeds demand, the price may decline; if demand exceeds supply, the price may rise. And the prices charged by different suppliers are also different, or due to process costs and operating strategies. To know the exact price, you must consult the chemical raw material supplier in detail, and negotiate the price based on quantity, quality, etc.