5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydro-2-Methyl-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid

This is the chemical structure analysis of 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid. Looking at its name, its structure can be deduced gradually.
"5- (tert-butoxycarbonyl) ", that is, at the 5th position of the main structure of the molecule, it is connected with tert-butoxycarbonyl. The structure of tert-butoxycarbonyl is -OC (CH 🥰), and this group is often used as an amino protecting group in organic synthesis.
"4,5,6,7-tetrahydro", indicating that the double bonds at positions 4, 5, 6, and 7 of the pyridine ring are hydrogenated, changing from the original pyridine aromatic ring to a partially saturated six-membered ring structure.
"2-methyl", shown in the second position of the main structure with methyl-CH.
"1H-pyrrolido [3,2-c] pyridine", revealing that the molecule is formed by fusing the pyrrole ring with the pyridine ring, and the fusing mode of the pyrrole ring with the pyridine ring is [3,2-c]. The pyrrole ring is a five-membered heterocyclic ring containing one nitrogen atom, and the pyridine ring is a six-membered aromatic ring containing one nitrogen atom.
"3-carboxylic acid" indicates that there is a carboxyl-COOH at position 3 of the main structure.
In summary, the chemical structure of 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid is pyrrolido-pyridine as the parent nucleus, methyl at position 2, carboxyl at position 3, pyridine ring moiety of hydrogenation at positions 4 to 7, and organic compound structure at position 5 with tert-butoxycarbonyl.

5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid, this is an organic compound. Its main uses are quite extensive, and it is often regarded as a key intermediate in the field of medicinal chemistry.
Due to the delicate organic synthesis, many drug molecules need to be constructed with this compound as a starting material or an important module. After specific chemical reactions, its structure can be modified and derived, and then molecules with specific biological activities can be obtained, which are expected to be developed as drugs for the treatment of various diseases. < Br >
In the field of chemical research, it is also an ideal substrate for exploring new reaction mechanisms and synthesis strategies. By studying its participation in reactions, chemists can gain insight into the influence of reaction paths and reaction conditions, and promote the development of organic synthetic chemistry. In addition, in related fields such as materials science, if its structure is cleverly designed and modified, it may endow materials with certain unique properties, showing potential application value.

The synthesis of 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid is quite complicated and requires several steps to achieve.
The first step is to react with a reagent with a tert-butoxycarbonyl (Boc) group, usually with a suitable starting material or a compound containing a pyridine structure. This reaction is designed to introduce tert-butoxycarbonyl, which is carried out under more mild organic synthesis conditions, such as dissolving the raw material in an inert gas-protected atmosphere with a specific organic solvent and adding a suitable base substance for catalysis. The base can assist the reaction of the starting material with the Boc reagent, so that the tert-butoxycarbonyl can be smoothly connected to the target check point.
In the next step, for the modification of the pyridine ring, to construct the tetrahydropyridine structure, hydrogenation is often required. Suitable hydrogenation catalysts, such as palladium carbon (Pd/C), can be used to react in a hydrogen atmosphere. This process requires precise control of the reaction temperature, hydrogen pressure and reaction time to promote the partial hydrogenation of the pyridine ring to form a 4,5,6,7-tetrahydropyridine structure.
Furthermore, for the introduction of 2-methyl, methylation reagents can be selected. According to the activity of the raw material and the reaction conditions, iodomethane, dimethyl sulfate, etc. are selected. During the reaction, the methyl group may be successfully substituted for the target hydrogen atom with the assistance of alkali substances.
Finally, the 3-carboxylic acid moiety is synthesized. Or it is achieved by hydrolysis, oxidation and other reactions. If the starting material contains hydrolyzable ester groups, hydrolyzed under suitable acid and alkali conditions, a carboxyl group can be obtained; or a specific group is oxidized to form a carboxyl group.
After each step of the reaction, the product needs to be purified by column chromatography, recrystallization and other means to remove impurities and obtain high-purity 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid. On the road of synthesis, it is necessary to carefully control the reaction conditions of each step in order to obtain the product smoothly.

5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid, the physical properties of this substance are as follows:
Looking at its morphology, at room temperature, it is mostly white to white solid, and powder or crystalline form is not uncommon. This is determined by the intermolecular forces and arrangement. The characteristics of its melting boiling point, the melting point is about [specific value (if known) ], and the boiling point varies according to the ambient pressure, usually boiling at a higher temperature. Because the molecular structure contains polar groups, such as carboxyl groups, it has a certain solubility in polar solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO). However, in non-polar solvents such as n-hexane and benzene, the solubility is very small.
The density of this substance is moderate, and the relative density is estimated according to its chemical structure and composition, and the relative density is about [approximate value (if known) ]. Its stability is good under normal conditions. However, in extreme environments such as strong acids, strong bases, or high temperatures and high humidity, the molecular structure may change, triggering chemical reactions. If the carboxyl group encounters a strong base, it can form a salt, and the tert-butoxycarbonyl group may be removed under acidic conditions.
In addition, this substance may be hygroscopic, because the carboxyl group can form hydrogen bonds with water molecules. When storing, pay attention to the ambient humidity and should be placed in a dry place to avoid deliquescence affecting its quality and properties. This is the common physical properties of 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid.

5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid, which is worth studying in detail in the current market prospect. It may have significant potential in the field of medicinal chemistry.
In recent years, the trend of pharmaceutical research and development has seen a great demand for innovative drugs. This compound has a unique structure and can be used as a lead compound as a cornerstone for the creation of new drugs. Many pharmaceutical companies and scientific research institutions are devoting their efforts to studying compounds with such structures, hoping to gain therapeutic targets such as neurological diseases and cardiovascular diseases.
Furthermore, in the field of organic synthesis chemistry, the refinement of its synthesis methods has also attracted extensive attention. If an efficient and green synthesis path can be developed, it will be able to significantly reduce its production costs and enhance market competitiveness. With the increasing maturity of chemical synthesis technology, new methods and new reagents continue to emerge, bringing hope for its large-scale preparation.
However, although the market prospect is bright, there are still challenges. Regulations and regulations are increasingly stringent, and the safety and effectiveness of compounds need to be tested. And similar competing products continue to emerge. If you want to occupy a place in the market, you must have a unique advantage.
In summary, the market prospect of 5- (tert-butoxycarbonyl) -4,5,6,7-tetrahydro-2-methyl-1H-pyrrolido [3,2-c] pyridine-3-carboxylic acid is promising, but it also needs to deal with many problems in order to take advantage of the situation and bloom in the market.