5-Methylpyridine-2-carboxylic acid

5-Methyl-2-furanoic acid has a wide range of main uses. In the field of medicine, this is an important pharmaceutical intermediate. The synthesis of many drugs often relies on it as a starting material or key intermediate. Through specific chemical reactions, it can be converted into compounds with specific pharmacological activities. For example, some drugs for the treatment of cardiovascular diseases can be prepared through a series of reactions, making great contributions to human health.
In the chemical industry, it is also an important organic synthesis raw material. It can be used to synthesize various polymer materials with excellent properties. In the synthesis of polyester high molecules, 5-methyl-2-furanoic acid can participate in the reaction, giving the polymer material special properties, such as better heat resistance, chemical resistance, etc. At the same time, in the field of coatings, adhesives, etc., it is also used to improve the performance and quality of products.
In the fragrance industry, 5-methyl-2-furanoic acid can be used as a raw material for fragrance synthesis. Due to its unique chemical structure, after appropriate reaction modification, it can generate compounds with unique aroma. These fragrances can be used in food, cosmetics and other industries to add a pleasant aroma to products. For example, it can prepare a unique fragrance for some high-end cosmetics to enhance the added value of products.
In addition, in the agricultural field, some compounds synthesized from 5-methyl-2-furanic acid can be used as pesticides or plant growth regulators. They can help crops resist pests and diseases, promote the growth and development of crops, and then improve the yield and quality of crops. In short, 5-methyl-2-furanic acid plays an indispensable role in many fields and is of great significance to promote the development of various industries.

5-Methyl-2-furanoic acid is an organic compound. Its physical properties are quite unique, let me tell you one by one.
Looking at its properties, under room temperature, 5-methyl-2-furanoic acid is mostly white to light yellow crystalline powder, like fine sand, with fine texture. Its color is light, reflecting the characteristics of molecular structure, and it is also one of the key characteristics for identifying this substance.
The melting point is about 133 ° C - 136 ° C. When the temperature gradually rises, the compound slowly melts from solid to liquid. The fixing of the melting point is just like human ethics, and it is not easily changed due to external disturbances. This is an inherent property of the substance, which is of great significance in identification and purity determination.
In terms of boiling point, it is usually around 272.4 ° C. At this high temperature, the compound will melt into gaseous state and dissipate. The level of boiling point is closely related to the intermolecular forces, indicating the stability of its internal structure.
Solubility is also an important physical property. 5-methyl-2-furanoic acid is slightly soluble in water, but it can be well dissolved in organic solvents such as ethanol and ether. This property is due to the fact that its molecules have both polar and non-polar parts. It is similar to the adaptability of humans to different environments. It shows different affinities in different solvents and is widely used in chemical production, separation and purification.
5-methyl-2-furanocarboxylic acid has sublimation properties, although it is not very significant. Under certain conditions, it is directly converted from solid to gaseous without going through a liquid state. This sublimation phenomenon is like the emergence of immortals. It adds a different path for material transformation in specific scenarios, and may be useful in some fine chemical and analytical tests.
This compound is relatively stable in air and does not react quickly with common gases such as oxygen. It is just like a gentleman who is unflappable and can stick to its own nature. However, exposure to strong light and high temperatures for a long time may also cause some changes, so it needs to be properly disposed of during storage to ensure its quality.

5-Methyl-2-furanoic acid has unique chemical properties. This compound is acidic and can be neutralized with bases due to the carboxyl group (-COOH). If it reacts with sodium hydroxide, the hydrogen in the carboxyl group dissociates, combines with hydroxide to form water, and forms 5-methyl-2-furanoic acid sodium salt and water. This reaction is often used in organic synthesis to adjust pH and prepare corresponding salts.
5-methyl-2-furanoic acid is easily decomposed when heated. Its structure contains a furan ring and a carboxyl group. When heated, the carboxyl group may decarboxylate, release carbon dioxide, and form 5-methylfuran. Under certain temperatures and conditions, this decomposition reaction will occur, and strict temperature control is required in research and production to avoid product loss or deterioration.
Its solubility is also an important property. It is slightly soluble in cold water because the carboxyl group can form hydrogen bonds with water, but the furan ring is a hydrophobic group, limiting the overall water solubility. However, it is easily soluble in organic solvents such as ethanol and ether. Due to the hydrophobic interaction between the furan ring and the organic solvent, the carboxyl group can form hydrogen bonds with some organic solvents, making it easier to dissolve. This property facilitates the separation and purification of the compound from the reaction system.
5-methyl-2-furanic acid can also undergo esterification reaction. Under the catalysis of acid, the carboxyl group reacts with alcohol to form an ester and water. For example, with methanol catalyzed by concentrated sulfuric acid, 5-methyl-2-furanoic acid methyl ester is formed with water, which is an important method for the preparation of ester flavors and other fine chemicals.

To prepare 5-methyluracil-2-potassium carboxylate, there are various methods. First, it can be obtained by heating 5-methyluracil and potassium carbonate in a suitable solvent. Among them, 5-methyluracil is the starting material, and potassium carbonate is the salt-forming agent. In the reactor, put an appropriate amount of 5-methyluracil and pour it into the solution of potassium carbonate. The solvent is usually water or alcohols, such as ethanol, methanol, etc., depending on the solubility of the reactants and the reaction conditions. The temperature is raised to a certain extent, usually controlled at 60-80 degrees Celsius, and the two are continuously stirred to fully react. After the reaction is completed, the crude product of 5-methyluracil-2-potassium carboxylate can be obtained by cooling and filtration, and then purified by recrystallization to obtain a pure product.
Second, the nucleophilic substitution reaction is carried out with 5-methyl-2-halogenated uracil and potassium carboxylate as raw materials. Halogenated, such as chlorine, bromide and the like. In the reaction system, an appropriate amount of organic solvents, such as N, N-dimethylformamide (DMF), dichloromethane, etc. are added to promote the dissolution and reaction of the reactants. Adding alkali substances, such as sodium carbonate, potassium carbonate, etc., adjusts the pH of the system, which is conducive to nucleophilic substitution reaction. Heat up to a suitable temperature, usually 40-60 degrees Celsius, when the number of reactions. After the reaction is completed, the solvent and impurities are removed by extraction, liquid separation, distillation and other operations, and the target product can also be obtained. The purity of the product is improved by subsequent refining steps.
Third, 5-methyluracil-2-carboxylic acid is used as raw material to react with potassium hydroxide. In the reaction vessel, 5-methyluracil-2-carboxylic acid is dissolved in an appropriate amount of solvent, such as water, and an aqueous solution of potassium hydroxide is added. The reaction is mild and can be carried out at room temperature or slightly heated. After the reaction, 5-methyluracil-2-carboxylate potassium can be obtained by concentration, crystallization and other operations. The raw materials are easy to obtain in this way, and the reaction conditions are mild. However, attention should be paid to the purity of the raw materials and the control of the reaction endpoint, so as not to affect the quality and yield of the product.

In today's market, the price of 5-methyl-2-furanoic acid is about thirty to fifty cents per catty. This price is not constant and often changes with market conditions. If the weather is smooth and the yield is abundant, the price may decrease; if in the event of a natural disaster, the harvest is sharply reduced, and the price must rise.
Furthermore, the situation of demand and supply is also great in the shadow of the price. If the merchants compete for this product, the supply is not enough, and the price is high; if the demand is scarce, and the supply exceeds the demand, the price will drop. In addition, the prices of various items in the market also affect each other. If the prices related to it change, the price of 5-methyl-2-furanoic acid may also change accordingly.
Therefore, if you want to know the exact price, you must always look at the market conditions, observe the weather, and ask for supply before you can know the price change. It is an appropriate policy for business and trade.