5-methylH-imidazo[1,2-a]pyridine-3-carbaldehyde

5-MethylH-imidazo [1,2-a] pyridine-3-carbalaldehyde, which is the English name of an organic compound. Based on the ancient classical text of "Tiangong Kaiwu", its chemical structure can be explained as follows:
The structure of this compound is based on imidazo [1,2-a] pyridine. Imidazo-pyridine is formed by fusing imidazole ring and pyridine ring, which is similar to the interlocking of two rings and interdependent and symbiotic. Its 1,2-a logo indicates the specific position and method of fusing the two rings, which is similar to the fit of mortise and tenon, and the positioning is accurate. < Br >
At the 5th position of the base frame, there is a methyl group attached. The methyl group is a simple group composed of carbon and hydrogen, like a side branch, connected to the main frame. At the 3rd position, there is an aldehyde group (-CHO) connected. The aldehyde group is active in nature and plays an important role in many reactions and properties of compounds. It is like a key organ of human beings and controls the change of characteristics. In this way, the chemical structure of 5-methylH-imidazo [1, 2-a] pyridine-3-carbalaldehyde, described here, gives a glimpse of the combination of its parts, which resembles a delicate creation, co-forming this unique organic molecule.

5-MethylH-imidazo [1,2-a] pyridine-3-carbalaldehyde, Chinese name or 5-methyl-H-imidazolo [1,2-a] pyridine-3-formaldehyde. This substance has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to synthesize compounds with specific biological activities. In the process of many drug development, molecules containing this structural unit need to be constructed, and their unique chemical properties can be used to achieve precise interaction with biological targets, thereby achieving the purpose of treating diseases.
In the field of materials science, it can participate in the preparation of functional materials. Due to its structure imparting special optoelectronic properties, it can be chemically modified or combined with other materials to prepare materials such as organic Light Emitting Diodes (OLEDs), sensors and other materials, which have great potential in the manufacture of optoelectronic devices.
In the field of organic synthetic chemistry, as an important synthetic building block, it can use a variety of chemical reactions, such as condensation and addition reactions involving aldehyde groups, to build complex organic molecules, open up paths for the synthesis of new organic compounds, and help the development and innovation of organic synthetic chemistry. With its unique structure and properties, this compound plays a key role in many fields and promotes the continuous progress of related science and technology.

5-MethylH-imidazo [1,2-a] pyridine-3-carbalaldehyde, that is, 5-methyl-H-imidazolo [1,2-a] pyridine-3-formaldehyde, is synthesized as follows:
First take a certain amount of 2-aminopyridine, place it in a reactor, add an appropriate amount of organic solvent, such as ethanol or dichloromethane, and stir to dissolve it uniformly. Then, slowly add an appropriate amount of α-bromoacetone dropwise, and add an appropriate amount of base, such as potassium carbonate or sodium carbonate, to promote the smooth progress of the reaction. The reaction process needs to be controlled at a certain temperature range, such as 40-60 ° C, and stirred continuously for several hours. This step aims to form 5-methylimidazo [1,2-a] pyridine intermediates.
After the previous reaction is completed, the resulting intermediate is transferred to another reaction vessel after appropriate post-treatment, such as filtration to remove solid impurities, and reduced pressure distillation to remove the solvent. Add a suitable oxidizing agent, such as manganese dioxide or Dess-Martin reagent, and then add an appropriate amount of organic solvent, such as dichloromethane, and stir the reaction at room temperature for several hours. The purpose of this oxidation step is to oxidize the group at a specific position of the intermediate to an aldehyde group to obtain 5-methyl-H-imidazolo [1,2-a] pyridine-3-formaldehyde. After the reaction is completed, it is purified by column chromatography or recrystallization to obtain high-purity target products.
Another synthetic route is to use 2-chloropyridine as the starting material, first react with methyl lithium reagent, and introduce methyl groups on the pyridine ring. Then cyclization occurs with cyanamide to generate 5-methyl imidazolo [1,2-a] pyridine. After Vilsmeier-Haack reaction, using the reagent system composed of phosphorus oxychloride and dimethylformamide, at an appropriate temperature, a specific position can be converted into an aldehyde group, and the final product 5-methyl-H-imidazolo [1,2-a] pyridine-3-formaldehyde is obtained. Subsequent purification operations are also required to obtain purified products.

5-MethylH-imidazo [1,2-a] pyridine-3-carbalaldehyde is a kind of organic compound. Its physical properties are quite inscrutable.
When it comes to appearance, it is often a crystalline solid, and its color is mostly white to light yellow. The shape is like a fine crystal, and the appearance is delicate. The formation of this state is determined by the interaction between molecules, and the molecules are arranged according to specific rules, so they form a crystalline state.
As for the melting point, it is about a specific temperature range. When the external temperature gradually rises to a certain value, the energy obtained by the molecules is enough to break through the lattice binding, the lattice structure disintegrates, and the substance changes from a solid state to a liquid state. The characteristics of this melting point are closely related to the molecular structure, and the strength of the intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., all determine the melting point.
Solubility is also an important physical property. In common organic solvents, such as ethanol, dichloromethane, etc., it has a certain solubility. This is because there are polar parts in the molecular structure of the compound, which can interact with the polar molecules of organic solvents, such as dipole-dipole interactions, to achieve dissolution. However, in water, its solubility is poor. Due to the tight hydrogen bond network between water molecules, the interaction between the compound and water is difficult to effectively break this network, so it is not easily soluble.
In addition, its density is also a fixed value. The size of the density reflects the amount of mass of a substance per unit volume, which is related to the molecular weight and the degree of intermolecular packing. The larger the molecular mass and the tighter the packing, the greater the density. The density of this compound is its inherent property and remains constant under specific conditions.
In summary, the physical properties of 5-methylH-imidazo [1,2-a] pyridine-3-carbalaldehyde, such as appearance, melting point, solubility, density, etc., are determined by its unique molecular structure, and have shown important uses in many fields such as organic synthesis and drug development.

I look at your question, but I am inquiring about the price range of 5-methylH-imidazo [1,2-a] pyridine-3-carbalaldehyde in the market. However, this product is not an unusually easy product, and its price in the market often changes due to multiple reasons.
First, if it is a high-purity and high-quality product used for scientific research, for fine chemical experiments, etc., its price must be high. Cover scientific research materials, strict requirements on purity, and complex preparation methods, so the price per gram can reach hundreds or even thousands of yuan.
Second, if it is used for industrial production of large-scale raw materials, depending on the amount of batches, the price is also different. When the batch size is large, the price per unit may be reduced to tens of yuan per gram due to the scale effect. However, if the quantity is small, the manufacturer's production cost allocation is high, and the price will also rise.
Third, the state of market supply and demand also affects its price. If there are many seekers and few suppliers, the price will rise; conversely, if the supply exceeds the demand, the price may decline.
And its source, quality grade, sales area, etc., are all related to the price. Therefore, it is not easy to determine the exact price range, which probably ranges from tens of yuan to thousands of yuan per gram. It is necessary to carefully consider the market conditions, quality and transaction scale.