5-methoxyimidazo-[4,5-b]pyridine-2-thiol

5-Methoxyimidazolo [4,5-b] pyridine-2-mercaptan is a unique organic compound. It has a wide range of uses and has shown its important value in many fields.
In the field of medicinal chemistry, this compound is often a key intermediate for the creation of new drugs. Due to its unique molecular structure, it can interact with specific targets in organisms. By modifying and optimizing its structure, medical researchers hope to develop therapeutic drugs with outstanding efficacy and mild side effects. For example, for the target of some specific diseases, 5-methoxyimidazolo [4,5-b] pyridine-2-thiol can be used as a lead compound. After a series of chemical modifications, it is expected to become a good medicine for the treatment of cardiovascular diseases, nervous system diseases or tumors.
In the field of materials science, it also has good performance. With its own chemical properties, it can participate in the construction of materials with special properties. For example, in the preparation of organic semiconductor materials, this compound can be used as a key component to endow the material with unique electrical and optical properties, and then applied to light organic Emitting Diode (OLED), organic solar cells and other optoelectronic devices to improve their performance and efficiency.
Furthermore, in the field of pesticide chemistry, 5-methoxyimidazolo [4,5-b] pyridine-2-thiol can be used as a basic raw material for the development of new pesticides. Due to its biological activity against certain pests or pathogens, through rational design and synthesis, it is expected to create high-efficiency, low-toxicity and environmentally friendly pesticide products, which will help the sustainable development of agriculture and ensure the harvest of crops.

There are many ways to synthesize 5-methoxy imidazolo [4,5-b] pyridine-2-mercaptan.
First, it can be started from a suitable pyridine derivative. The methoxy group is introduced at a specific position of the pyridine ring first, and this step often depends on the nucleophilic substitution reaction. The introduction of methoxy groups needs to be precisely controlled at the check point, which is related to the subsequent reaction process and the structure of the final product. Next, the construction of the imidazole ring structure often goes through a series of reactions such as condensation and cyclization by means of nitrogen-containing and sulfur-containing reagents. In the cyclization stage, the regulation of reaction conditions is quite critical, such as temperature, reaction time, type and amount of catalyst, which all have a significant impact on the cyclization efficiency and product purity.
Second, it is also feasible to use imidazopyridine as the starting material. First, the imidazopyridine parent is modified to introduce methoxy groups, which may be achieved by metal-catalyzed reactions. Subsequently, thiol groups are introduced at the 2-position of the pyridine ring. This introduction process can be selected from a specific sulfur source, and the directional access of thiol groups can be achieved under appropriate base and reaction conditions.
Furthermore, one-pot synthesis can be tried. All kinds of starting materials are required in the same reaction system, and the target molecule is constructed in one step through carefully designed reaction steps and conditions. Although this method is challenging, if successfully implemented, it can simplify the operation process, improve the reaction efficiency, reduce the cumbersome steps of intermediate product separation, and reduce production costs. However, the one-pot method requires extremely high synergy of reaction conditions, and each step of the reaction needs to be adapted to each other in order to proceed smoothly.
No matter what kind of synthesis method is used, the reaction products at each step need to be carefully separated and purified, and column chromatography and recrystallization are often used to ensure that the purity of the products meets the requirements, so as to lay a solid foundation for subsequent research and application.

5-Methoxyimidazolo [4,5-b] pyridine-2-mercaptan, this is an organic compound with unique physical properties. It is mostly solid at room temperature and pressure, and its appearance may be powdery. The color is often white to light yellow, the texture is fine, and it is dry to the touch.
Looking at its solubility, this compound has limited solubility in water. However, in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it shows good solubility characteristics. This property is crucial in the process of chemical synthesis and drug development, when selecting a suitable solvent to promote the smooth progress of the reaction or to achieve uniform dispersion of the compound.
When it comes to melting point, 5-methoxyimidazolo [4,5-b] pyridine-2-thiol has a specific melting point value, which is an important indicator of the purity and structural stability of a compound. Accurate determination of the melting point can help determine the purity of the compound. When the purity of the compound is high, the melting point range is relatively narrow; if it contains impurities, the melting point may be reduced and the melting point range will also be widened.
As for the boiling point, although it may be difficult to observe its boiling phenomenon under normal pressure, under reduced pressure, as the temperature increases, the compound will reach the boiling point and then vaporize. The relevant data of boiling point is of great significance for controlling temperature conditions to achieve effective separation in chemical operations involving separation and purification.
In addition, the density of this compound is also an important physical property parameter. The density determines its floating state in different media, and can provide a theoretical basis for operation in some processes involving liquid-solid or liquid-liquid separation.
In terms of spectral properties, through infrared spectroscopy (IR), the absorption peaks corresponding to specific functional groups can be observed, such as the C-O stretching vibration peak of methoxy group and the S-H stretching vibration peak of thiol group, etc., thus providing strong evidence for its structure identification. Nuclear magnetic resonance spectroscopy (NMR), whether it is hydrogen spectroscopy (e.g. H NMR) or carbon spectroscopy (e.g. C NMR), can provide information on hydrogen and carbon atoms in different chemical environments in a molecule, which helps to further clarify its molecular structure.

The price range of 5-methoxyimidazolo [4,5-b] pyridine-2-mercaptan is difficult to determine in the market. The price of this compound in the market of chemical raw materials often varies due to multiple factors.
First, the cost of raw materials has a great impact. If the price of starting materials, solvents, reagents, etc. required for the synthesis of this compound fluctuates, the price of the product will also move. If the starting material is scarce or difficult to prepare, its price will rise, causing the price of 5-methoxyimidazolo [4,5-b] pyridine-2-mercaptan to rise.
Second, the process complexity and scale of production are related to its price. If the synthesis process is cumbersome, multi-step reaction, strict reaction conditions and high-end equipment are required, the production cost will be high, and the product price will also be high. On the contrary, in large-scale production, the unit cost may be reduced due to the scale effect, and the price may also be reduced.
Furthermore, the supply and demand relationship in the market is the key. If the demand for this compound in the fields of medicine and materials increases sharply, but the supply is limited, the price will rise; if the market is oversupplied, the merchant may reduce the price in order to sell its goods.
In addition, the brand of the manufacturer, Quality Standards and sales regions will also make the price different. Well-known manufacturers, high standard quality, the price may be higher; different regions have different prices due to different transportation costs and market competition.
In summary, the price of 5-methoxyimidazolo [4,5-b] pyridine-2-thiol in the city today ranges from a few yuan to several hundred yuan per gram, but the actual price needs to be consulted with each supplier, according to the current market conditions.

5-Methoxyimidazolo [4,5-b] pyridine-2-mercaptan is a special chemical substance. Its storage conditions are crucial to the stability and quality of this substance.
This substance should be stored in a cool, dry and well-ventilated place. A cool environment can avoid high temperature causing its chemical properties to change. High temperature often accelerates chemical reactions, or causes decomposition and deterioration, which impairs its original characteristics. Dry conditions are also indispensable, because moisture is prone to deliquescence, which in turn triggers many adverse reactions. Moisture may interact with the substance to change its structure or purity.
Furthermore, good ventilation can keep the air in the storage environment fresh, avoid the accumulation of harmful gases or steam, and avoid the latent risk caused by excessive local concentration.
In addition, the storage place should be away from fire sources, heat sources and strong oxidants. Needless to say, fire sources and heat sources can cause combustion or even explosion; strong oxidants are highly oxidizing, and contact with the substance may cause severe oxidation reactions, endangering safety and quality.
When storing, it should also be contained in a suitable container. This container must have good chemical stability, do not react with the substance, and can be effectively sealed to prevent leakage and external factors from interfering.
In conclusion, following the above storage conditions, 5-methoxyimidazolo [4,5-b] pyridine-2-thiol can be properly stored to maintain its chemical stability for subsequent use.