5-Methoxycarbonyl-2,6-dimethyl-4(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

This is an organic compound with a long and complicated name, 5-methoxycarbonyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid is also. To clarify its chemical structure, it is necessary to analyze it according to the naming rules.
"5-methoxycarbonyl" refers to the 5 position of the pyridine ring with a methoxycarbonyl group, which is composed of a methoxy group connected to a carbonyl group. "2,6-dimethyl" indicates that the 2 and 6 positions of the pyridine ring have one methyl group each. " 4 (3-nitrophenyl) "means that the 4th position of the pyridine ring is connected to a phenyl group, and the 3rd position of the phenyl group has a nitro group." 1,4-dihydropyridine "reveals that the core structure of the compound is a dihydropyridine ring, and the 1st and 4th positions are occupied by hydrogen atoms." 3-carboxylic acid "indicates that there is a carboxyl group at the 3rd position of the pyridine ring.
Its overall chemical structure is centered on the dihydropyridine ring, and each substituent is connected to the corresponding position in sequence, showing a specific spatial arrangement and chemical characteristics. This structure determines that the compound may have unique reactivity and potential application value in the fields of organic synthesis, medicinal chemistry, etc.

5-Methoxycarbonyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid is widely used in the fields of medicine and chemical industry.
In the field of medicine, it is a key organic synthesis intermediate and often appears in the creation of cardiovascular drugs. Many drugs for the treatment of hypertension and angina pectoris rely on it as a raw material. Due to its unique structure, the cap can act on specific targets in the cardiovascular system, regulate blood pressure and relieve angina pectoris symptoms. Its value in the field of drug development is like a cornerstone in a high-rise building, providing an important starting material for the development of new drugs.
In the chemical industry, it can be used to prepare materials with special properties. Because it contains specific functional groups, it can participate in polymerization reactions, etc., to synthesize polymer materials with unique optical, electrical or mechanical properties. Such materials may be applied to the manufacture of electronic devices and optical instruments, contributing to the innovation of chemical materials.
Furthermore, at the level of scientific research and exploration, because of its complex structure and active check point, it is the research object of organic synthetic chemistry. Scholars can use the study of its reaction characteristics and derivatization paths to expand the knowledge of organic synthesis methodologies, provide ideas and methods for the creation of more complex organic molecules, and promote the development of organic chemistry.

The synthesis method of 5-methoxycarbonyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid has many complicated ways. The following common methods are expected to solve your confusion.
First, the classic Hantzsch reaction pathway. Methyl acetoacetate, 3-nitrobenzaldehyde and ammonium bicarbonate are used as raw materials. In an alcohol solvent, such as ethanol, an appropriate amount of catalyst, such as glacial acetic acid, is added and refluxed. In the meantime, the raw materials interact and undergo steps such as condensation and cyclization to form the target product. The reaction conditions are mild and the operation is convenient. However, it is necessary to pay attention to the control of the ratio of raw materials and the reaction time to prevent the growth of side reactions and poor yield.
Second, the method of microwave-assisted synthesis. With similar raw materials, place them in a microwave reactor, select suitable solvents and catalysts, and use the power of microwave radiation to accelerate the reaction process. The effect of microwave can make molecules vibrate and collide rapidly, making the reaction proceed efficiently, and the reaction time is greatly reduced, and the yield may also be improved. However, this equipment is special and not available everywhere, and the reaction parameters need to be carefully adjusted.
Third, metal catalytic synthesis method. Select specific metal catalysts, such as some transition metal complexes, in a specific reaction system to catalyze the reaction of raw materials. Metal catalysts can effectively reduce the activation energy of the reaction, guide the reaction in the direction of generating the target product, and improve the selectivity and yield of the reaction. However, metal catalysts may be more expensive, and the separation and recovery after the reaction need to be properly handled to avoid affecting the purity and production cost of the product.
These methods have their own advantages and disadvantages. In practice, it is necessary to carefully choose the appropriate synthesis method according to the experimental conditions, raw material availability, cost considerations and other factors to achieve the best synthesis effect.

5-Methoxycarbonyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid, which is an organic compound. Its physical properties are quite critical and are related to many fields of application.
Looking at its properties, at room temperature and pressure, it is mostly in a solid state, or in a crystalline state, and its appearance often has a certain color. However, the specific color varies depending on factors such as purity, or is white, off-white, or slightly yellowish.
Talking about melting point, this is an important physical constant. After experimental determination, its melting point is in a specific temperature range, which is crucial for identifying the compound and determining its purity. The melting point of the compound with different purity may vary slightly. The higher the purity, the closer the melting point is to the theoretical value.
In terms of solubility, it shows a variety in organic solvents. In common organic solvents such as ethanol and dichloromethane, it has a certain solubility and can be dissolved to form a uniform solution. In water, it has poor solubility and is mostly insoluble or slightly soluble. This difference in solubility has a profound impact on the separation, purification and reaction operation of the compound.
Density is also one of the physical properties of the compound. Its density value is specific, and density data is indispensable when it comes to mass and volume conversion, as well as distribution within a specific system.
In addition, the stability of this compound also belongs to the category of physical properties. Under general conditions, it has a certain stability, but in case of high temperature, strong light, specific chemical environment, or chemical changes, the stability is affected. This stability characteristic needs to be taken into account during storage, transportation and use.

5-Methoxycarbonyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid, this compound is used in the field of medicinal chemistry, with promising prospects and great potential.
In the current market, it has emerged in the field of cardiovascular disease drug development and shines. Many studies have shown that such dihydropyridine compounds are effective in calcium channel blockade. Therefore, in the process of drug creation for the treatment of hypertension, angina pectoris and other diseases, it is often a key raw material and is highly relied on.
And because of its unique chemical structure, it is also a hot intermediate in the field of organic synthetic chemistry. With its structural properties, chemists can use it to construct a multi-component and complex organic molecular structure, paving the way for the development of new drugs and functional materials.
Furthermore, with the advancement of science and technology, drug screening and design technologies are changing with each passing day, and this compound plays an increasingly important role in the optimization process of lead compounds. Developers can refine and modify it based on its structure to find innovative drugs with better activity and safety.
From this perspective, 5-methoxycarbonyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid is used in the pharmaceutical and organic synthesis markets, just like a shining star, the light is just beginning to shine, and the future development path will be vast and promising for the progress of human health and materials science.