5-Methoxy-3H-imidazo[4,5-b]pyridine-2-thiol

5-Methoxy-3H-imidazolo [4,5-b] pyridine-2-mercaptan is an organic compound with specific chemical properties. Its structure contains an imidazolo-pyridine ring, and the methoxy group and the mercaptan group are connected to specific positions.
This compound has high reactivity because it contains a thiol group. The sulfur atom in the thiol group has lone pairs of electrons, which are easy to participate in nucleophilic substitution reactions. It can react with electrophilic reagents such as halogenated hydrocarbons to form new carbon-sulfur bonds and obtain derivatives with diverse structures. These reactions are of great significance in the field of organic synthesis and can be used to create compounds with different functions and properties.
Its methoxy group is the power supply group, which affects the molecular electron cloud distribution and has a great influence on the reactivity and selectivity of the compound. Due to the methoxy group power supply effect, the electron cloud density of the imidazolopyridine ring increases, and it is easier to react at a specific position in the electrophilic substitution reaction, which determines the selectivity of the reaction check point.
In addition, the solubility and stability of the compound are also affected by the groups in its structure. The relative polarity of thiol groups is large, which contributes to the solubility of the compound in polar solvents; while methoxy groups affect the overall polarity and spatial structure of the molecule, which in turn affects its stability. Under different environmental conditions, the stability varies. In case of specific oxidants, thiol groups may be oxidized to sulfonic acid groups and other sulfur-containing functional groups.
In summary, 5-methoxy-3H-imidazolo [4,5-b] pyridine-2-thiol has a unique structure, rich chemical reactivity and diverse physical and chemical properties, and may have potential application value in organic synthesis, medicinal chemistry and other fields.

To prepare 5-methoxy-3H-imidazolo [4,5-b] pyridine-2-mercaptan, there are various methods. Ancient chemists, in the way of organic synthesis, also follow the logic.
First, you can start from suitable pyridine derivatives. Choose a pyridine containing a specific substituent, and introduce a methoxy group and an imidazole ring structure through multiple delicate transformations. First, pyridine is used as a group, and a halogen atom is introduced at a specific position on its ring by halogenation. This halogen atom is a key check point for subsequent reactions. After nucleophilic substitution, methoxy is introduced. In this step, a suitable nucleophilic reagent needs to be selected. Under appropriate reaction conditions, the nucleophilic reagent reacts smoothly with halogenated pyridine to obtain a methoxy-containing pyridine intermediate.
Then, an imidazole ring is constructed. When a sulfur-containing reagent is used to react with a pyridine intermediate to form an imidazole ring, a thiol group is also introduced. The reaction conditions in this step are harsh, and factors such as temperature and pH need to be carefully adjusted to make the reaction proceed in the expected direction to obtain the target product 5-methoxy-3H-imidazolo [4,5-b] pyridine-2-thiol.
Second, or starting from imidazole derivatives. Select an imidazole with a suitable substituent, construct a pyridine ring through a series of reactions, and introduce methoxy and mercaptan groups. First, the imidazole is modified to have an activity check point connected to the pyridine ring. Pyridine fragments are connected to the imidazole by condensation reaction and other methods to construct an imidazole-pyridine skeleton. Subsequently, methoxy is introduced through methoxylation reaction, and thiol is introduced through thiolation reaction. This process requires careful consideration of the reaction conditions at each step to ensure the purity and yield of the product.
The process of synthesis is like a craftsman's carving. Every step requires careful attention, insight into the reaction mechanism, weighing the advantages and disadvantages, and choosing the best method to make the synthesis smooth and obtain pure 5-methoxy-3H-imidazolo [4,5-b] pyridine-2-thiol.

5-Methoxy-3H-imidazolo [4,5-b] pyridine-2-thiol is useful in many fields. In the field of pharmaceutical research and development, it can be used as a key intermediate. When doctors explore new drugs, they often rely on various compounds as the cornerstone. After ingenious modification and splicing, they will eventually become good medicines. 5-methoxy-3H-imidazolo [4,5-b] pyridine-2-thiol has this potential, or can be derived into drugs that have curative effects on specific diseases, such as for some difficult diseases, to help medical treatment overcome difficulties.
In the field of materials science, it also has a place to be applied. Materials scholars study new materials, and this compound may participate in the construction of special functional materials due to its unique structure and properties. Or it can enhance the stability of the material, so that it can maintain good performance in different environments; or it can endow the material with special optical and electrical properties, which can be used in frontier fields such as optoelectronic devices.
Furthermore, in the process of organic synthesis, 5-methoxy-3H-imidazolo [4,5-b] pyridine-2-thiol provides rich possibilities for synthesis experts. Chemists use their unique activity check points to carefully design reaction paths to create more complex and functional organic molecules, which promote the continuous development of organic synthetic chemistry and deliver a variety of novel compounds to various industries.

I don't know what the price range of 5 - Methoxy - 3H - imidazo [4,5 - b] pyridine - 2 - thiol is in the market. Due to the change of the city, it is fickle and subject to various factors. The price may vary depending on the origin. If the product is abundant and of good quality, the price may be slightly lower; if the origin is remote and the output is rare, the price may be high.
Moreover, the trend of supply and demand in the market is also the main reason. If there are many applicants and there are few suppliers, the price will rise; if the supply exceeds the demand, the price may fall. Furthermore, the difficulty of preparing this product is related to the cost and also affects its price. If the preparation technique is complicated and requires a lot of materials and working hours, the cost will be high, and the price will rise accordingly; if the preparation method is simple and the cost is low, the price may be close to the people.
In addition, the competition in the market and the strategy of the merchants are all related to the price. If there is a competition in the same industry, the merchants may reduce the price in order to occupy the market; if there is only one company, they may be able to control the price. However, I do not have detailed market information at hand, and it is difficult to determine the price range.

5 - Methoxy - 3H - imidazo [4,5 - b] pyridine - 2 - thiol is an organic compound. To know its stability, it is necessary to study its molecular structure and chemical properties in detail.
This compound contains the core structure of imidazolopyridine, and is connected with methoxy and thiol groups. Methoxy groups have a electron charge effect, which can affect the distribution of molecular electron clouds or enhance their stability under certain reaction conditions. The electronegativity and bonding properties of sulfur atoms in thiol groups also have an important impact on the overall stability.
Usually, the stability of organic compounds is affected by many factors. From the perspective of chemical bonds, the bond energy of intramolecular covalent bonds is crucial. If the covalent bond energy between atoms is high, the molecule becomes more stable. In this compound, the carbon-carbon, carbon-nitrogen and other covalent bonds in the ring system, as well as the bonds between methoxy and thiol groups and the ring system, are the keys to determine the stability.
Environmental factors cannot be ignored. When the temperature increases, the thermal motion of the molecule intensifies, which may weaken the chemical bond and reduce the stability. In the acid-base environment, this compound may undergo protonation, deprotonation, or chemical reaction with acid and base due to the inclusion of heteroatoms such as nitrogen, oxygen, and sulfur, thereby changing its stability.
In addition, light may also affect its stability. Some organic compounds can cause luminescent chemical reactions under light, resulting in molecular structure changes.
Overall, the stability of 5-Methoxy-3H-imidazo [4,5-b] pyridine-2-thiol requires comprehensive consideration of its molecular structure, chemical bond properties, and external environmental factors such as temperature, acid-base, and light.