5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid

5-Methyl-1H-indazolo [2,3-c] pyridine-2-carboxylic acid has a wide range of uses. It plays a key role in the field of pharmaceutical research and development. Numerous studies have shown that based on this framework, chemically modified and modified, a series of compounds with unique biological activities can be created. For example, some of its core derivatives have emerged in the development of anti-tumor drugs, which can effectively inhibit the proliferation of specific tumor cells or induce tumor cell apoptosis, providing a new strategy and direction for conquering tumor diseases.
In the field of organic synthesis chemistry, 5-methyl-1H-indazolo [2,3-c] pyridine-2-carboxylic acid is also an indispensable intermediate. With its unique molecular structure and reactivity, it can participate in the construction of many complex organic compounds. By ingeniously designing chemical reaction pathways and using it as a starting material, organic molecules with special structures and functions can be efficiently synthesized, which have potential applications in materials science, total synthesis of natural products and other fields.
In addition, in biochemical research, this compound can be used as a tool molecule to explore the mechanism of specific biochemical reactions in organisms, help researchers gain insight into the mysteries of life processes, and provide strong support for basic research in related fields. In summary, 5-methyl-1H-indazolo [2,3-c] pyridine-2-carboxylic acids have important uses in many important fields and are of great significance for promoting scientific research and technological development.

The physical properties of 5-methoxy-1H-indazolo [2,3-c] indazolo-2-carboxylic acid are as follows:
This compound is mostly solid at room temperature. Looking at its color, or white to off-white powder, this is due to the nature of the atomic arrangement and electron cloud distribution in its molecular structure, which reflect light in the visible light band.
When it comes to the melting point, it is within a specific temperature range. This is due to the intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., at this temperature, it is sufficient to be overcome by thermal energy, causing the lattice structure to disintegrate, and the substance changes from a solid state to a liquid state. The specific melting point value depends on the accurate experimental determination, and it may be slightly affected by different purification methods and crystallization conditions.
Its solubility is also an important physical property. In common organic solvents, some organic solvents can show a certain solubility. For example, in polar organic solvents, such as dimethyl sulfoxide (DMSO), due to the polarity of DMSO and the polar interaction of the partial groups of the compound, the molecules can be uniformly dispersed and show a good solubility situation. In alcohols, such as methanol and ethanol, the degree of solubility depends on factors such as the ability to form hydrogen bonds between the compound and the alcohol molecules, or there is a certain amount of solubility. However, non-polar organic solvents, such as n-hexane, do not match the intermolecular forces of the compound, so they dissolve very little or almost insoluble.
In addition, the density of the compound is also a key physical property. Although the exact density value needs to be measured by precise experiments, it can be estimated roughly according to the molecular structure and the relative atomic mass of the constituent atoms, combined with theoretical models. The value of density reflects the degree of close packing of molecules, which is closely related to its crystal structure and intermolecular distance.
As for the stability of its physical properties under different temperatures and pressures, it is also the focus of research. As the temperature increases, the thermal movement of molecules intensifies, causing their crystal forms to change and decompose, etc.; pressure changes may also affect their molecular spacing and crystal structure, thereby changing physical properties such as density and melting point.

To prepare 5-methyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid, there are various methods.
First, the corresponding pyridine derivative can be started. First, the methyl group is introduced at a suitable position on the pyridine ring, which may be by means of nucleophilic substitution. The methyl-containing reagent reacts with the pyridine derivative, and the reaction conditions, such as temperature, solvent and catalyst, are carefully regulated, so that the methyl group is precisely connected to the expected check point. Then, the pyrrole ring is constructed by cyclization reaction. Here, it may be necessary to use a specific catalyst and the reactant to interact with specific groups in the molecule through multi-step transformation to form a pyrrole-pyridine structure. Finally, the obtained product is appropriately modified to introduce a carboxyl group at a specific position, which can be achieved by hydrolysis, oxidation and other reactions. This needs to be fine-tuned according to the specific substrate and reaction conditions.
Second, pyrrole derivatives are used as starting materials. First, the pyrrole ring is modified, and a suitable substituent is introduced to lay the foundation for subsequent connection with the pyridine ring. A suitable group can be introduced at a specific position of the pyrrole ring through reactions such as electrophilic substitution for subsequent cyclization reactions. Subsequently, by reacting with pyridine-related compounds, the pyridine part is constructed and the cyclization of the two is achieved to form the pyrrolido [2,3-c] pyridine structure. After cyclization, a carboxyl group is introduced at the target position through a specific reaction. This process also requires detailed investigation of the reaction conditions to ensure the selectivity and yield of the reaction.
Third, other heterocyclic compounds are also used as raw materials and converted through multiple steps. First, the heterocyclic compound is gradually converted into an intermediate with a partial structure of the target molecule through a series of reactions, or involves various reactions such as functional group conversion and carbon-carbon bond formation. After that, the pyrrolido-pyridine framework is established through key cyclization steps, and then carboxyl groups are introduced. This path requires detailed planning of each step of the reaction to ensure that the intermediate is stable and the subsequent reaction is easy to control.
All synthesis methods have advantages and disadvantages. In practice, the choice needs to be weighed according to the availability of raw materials, the difficulty of reaction conditions, cost and yield, etc., in order to efficiently prepare 5-methyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid.

5-Methyl-1H-indazolo [2,3-c] pyridine-2-carboxylic acid, which is used in medicine, pesticides, material science and other fields.
In the field of medicine, it is a key intermediate for the creation of new drugs. Due to its specific chemical structure and biological activity, it can play a role in a variety of disease-related targets. For example, for some tumor cells, it can precisely regulate cell signaling pathways, inhibit tumor cell proliferation and induce apoptosis, opening up new paths for the development of anti-tumor drugs; in neurological diseases, it can regulate neurotransmitter transmission and nerve cell activity, or become a core component of drugs for the treatment of neurodegenerative diseases. < Br >
In the field of pesticides, it shows excellent application potential. With its unique chemical properties, it has significant repellent, growth inhibition or poisoning effects on many pests. Not only can it effectively control crop pests, ensure crop yield and quality, but it is also more environmentally friendly and has less residues than traditional pesticides, which is conducive to sustainable agricultural development.
In the field of materials science, it has also made a name for itself. Due to its special optical and electrical properties, it can be used to prepare new photoelectric materials. For example, when applied to organic Light Emitting Diode (OLED), it can optimize the luminous efficiency and stability of the device and improve the display effect; in the preparation of sensor materials, the high sensitivity response characteristics to specific substances can accurately detect environmental pollutants or biomarkers.

5-Methyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid is a unique organic compound. Its market prospect is quite promising, and it is in demand in many fields.
In the field of pharmaceutical research and development, such compounds containing nitrogen heterocyclic structures exhibit significant biological activity. Studies have shown that they may be used as potential drug intermediates for the synthesis of drug molecules with specific pharmacological activities. For example, in the process of anti-tumor drug development, many compounds containing pyrrolido-pyridine structures have been proven to have inhibitory effects on the proliferation of tumor cells, providing key structural templates for the creation of new anti-tumor drugs. Therefore, in the field of medicine, with the increasing demand for innovative drugs, the market demand for 5-methyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acids, as an important intermediate, is expected to continue to grow.
In the field of materials science, nitrogen-containing heterocyclic compounds have potential applications in organic optoelectronic materials due to their unique electronic structures and chemical properties. 5-Methyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid can be used as a building unit to participate in the synthesis of materials with special optical and electrical properties, such as functional materials for organic Light Emitting Diodes (OLEDs), solar cells and other devices. With the rapid development of materials science, the demand for such compounds with special structures and properties will gradually increase.
However, the market for this compound also faces certain challenges. The synthesis process may be more complex, and cost control has become an important factor affecting its marketing activities. If breakthroughs can be made in the synthesis process and production costs can be reduced, its market competitiveness will be greatly enhanced. Furthermore, with the increasing market demand for green and environmentally friendly products, the degree of greening of the synthesis process also needs to be further considered to conform to the concept of sustainable development. Overall, the market for 5-methyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid has broad prospects, but it also needs to meet the challenges of synthesis cost and greening.