5 Methoxy 1 3 Dihydro 2h Imidazo 4 5 B Pyridine 2 Thione
pyridine pyrrole pyrazine piperidine piperazine

5-methoxy-1,3-dihydro-2H-imidazo[4,5-b]pyridine-2-thione

    Specifications

    HS Code

    890207

    Name 5-methoxy-1,3-dihydro-2H-imidazo[4,5-b]pyridine-2-thione
    Chemical Formula C7H7N3OS
    Molar Mass 181.215 g/mol
    Solubility In Water Low (organic compound with polar and non - polar regions)
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF

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    Frequently Asked Questions

    As a leading 5-methoxy-1,3-dihydro-2H-imidazo[4,5-b]pyridine-2-thione supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 5-methoxy-1, 3-dihydro-2H-imidazo [4,5-b] pyridine-2-thione?
    5-Methoxy-1,3-dihydro-2H-imidazolo [4,5-b] pyridine-2-thione, which is an organic compound. Its molecular structure includes the parent nucleus structure of imidazolo-pyridine. The imidazolo-pyridine parent nucleus is formed by fusing an imidazole ring with a pyridine ring, presenting a unique cyclic structure. At position 5, the methoxy group is connected by a methyl group and an oxygen atom, and then connected to the parent nucleus. At positions 1 and 3, it is a dihydrogen structure, which means that the carbon atoms at these two positions are connected to the hydrogen atom, which is two less double bonds than the completely unsaturated state of the parent nucleus. And position 2 is a thione group, that is, the carbon atom and the sulfur atom are connected by a double bond, and the carbon atom is also connected to the parent nucleus.
    The structure of this compound is unique, and each group interacts with each other, giving it specific physical and chemical properties. Due to the existence of methoxy groups, it will affect the electron cloud distribution of the molecule and change its lipophilicity and reactivity. The chemical properties of thione groups are active and can participate in many chemical reactions, which may be of great significance for the biological activity and application of this compound. From its structure, it can be inferred that it may have potential uses in organic synthesis, medicinal chemistry, and other fields. Due to its unique structure, it may interact with specific biological targets and exhibit unique biological activities.
    What are the main uses of 5-methoxy-1, 3-dihydro-2H-imidazo [4,5-b] pyridine-2-thione?
    5-Methoxy-1,3-dihydro-2H-imidazolo [4,5-b] pyridine-2-thione, which has a wide range of uses. In the field of medicine, it can be used as a key intermediate in drug synthesis. Due to its unique chemical structure and activity, it can help to construct compounds with specific pharmacological activities. After modification and derivatization, it is expected to develop new therapeutic drugs, such as targeted drugs for specific diseases, or improvements to existing drugs to improve efficacy and reduce side effects.
    In the field of materials science, some of its properties may be used to prepare special functional materials. For example, using its interaction characteristics with other substances to develop materials with specific adsorption, catalytic or optical properties may have applications in sensors, catalyst carriers, etc.
    In the field of agriculture, after rational design and modification, it can be made into pesticides or plant growth regulators. By virtue of its impact on specific physiological processes in organisms, it can achieve pest control or regulate plant growth and development, and improve crop yield and quality.
    In organic synthetic chemistry, as an important synthetic building block, it participates in the construction of many complex organic molecules. Because its structure contains heteroatoms such as nitrogen and sulfur, it provides a variety of reaction check points for synthetic reactions. Through ingenious design of reaction paths, organic compounds with novel structures and unique functions can be synthesized, laying the foundation for organic chemistry research and new material development.
    What are the synthesis methods of 5-methoxy-1, 3-dihydro-2H-imidazo [4,5-b] pyridine-2-thione?
    The synthesis method of 5-methoxy-1,3-dihydro-2H-imidazolo [4,5-b] pyridine-2-thione is rarely described in ancient books, and it is hoped that it will be helpful to describe it in detail.
    To prepare this substance, one method can be initiated by the corresponding pyridine derivative. First, the methoxy group is introduced with a suitable pyridine compound under specific reaction conditions. The introduction of the methoxy group requires careful selection of the reaction reagents and conditions, such as a halogenated methoxy reagent, catalyzed by a base, and reacted in a suitable solvent to achieve the purpose of precise introduction of the methoxy group. < Br >
    Then, the structure of imidazolo-pyridine is constructed by cyclization reaction. This step may require the help of special reaction aids, or under specific environments such as high temperature and high pressure, the specific groups of the pyridine derivative interact to form a cyclic imidazolo [4,5-b] pyridine structure.
    As for the formation of thionones, on the basis of the above products, thio reagents, such as Lawesson reagents, etc., can be used to heat the reaction under the protection of inert gas to convert the hydroxyl group into thionone group, so as to obtain 5-methoxy-1,3-dihydro-2H-imidazolo [4,5-b] pyridine-2-thionone.
    Alternatively or from imidazole derivatives, the pyridine ring can be gradually constructed and methoxy and thionone groups can be introduced. First, imidazole is used as the starting material, and through a series of substitution reactions, specific substituents are introduced to prepare for the subsequent construction of pyridine rings. Then through ingenious reaction design, the pyridine ring is spliced on the imidazole structure, while taking into account the introduction or transformation of methoxy and thione groups. This process requires fine regulation of reaction steps and conditions to ensure the purity and yield of the target product.
    However, each method has its own advantages and disadvantages. In actual operation, it needs to be selected according to specific circumstances, such as the availability of raw materials, the difficulty of reaction, and cost considerations.
    What are the physicochemical properties of 5-methoxy-1, 3-dihydro-2H-imidazo [4,5-b] pyridine-2-thione?
    5-Methoxy-1,3-dihydro-2H-imidazolo [4,5-b] pyridine-2-thione, this is an organic compound. Its unique physical and chemical properties are crucial for studying chemical synthesis, medicinal chemistry and other fields.
    When it comes to physical properties, this compound may be a solid under normal conditions, with a specific melting point and boiling point. The melting point is closely related to the intermolecular force. If the intermolecular force is strong, such as hydrogen bonds, van der Waals forces, etc., it requires more energy to make the molecule break away from the lattice structure, and the melting point is high; otherwise, it is low. The boiling point is the same, which is related to the energy required for the molecule to change from the liquid state to the gas state.
    Looking at its chemical properties, the molecular structure contains imidazolopyridine ring and thione group, giving it a variety of reactivity. In thione groups, sulfur atoms have lone pairs of electrons, which can be used as nucleophilic reagents and undergo nucleophilic substitution reactions with electrophilic reagents. For example, when reacting with halogenated hydrocarbons, sulfur atoms attack the carbon atoms of halogenated hydrocarbons, and halogen ions leave to form new sulfur-containing compounds.
    At the same time, the nitrogen atom of the imidazolopyridine ring also has lone pairs of electrons, which can participate in coordination reactions and form complexes with metal ions. Such complexes may have applications in the field of catalysis, where metal ions can coordinate with nitrogen atoms to change their own electron cloud density and spatial structure, thereby affecting catalytic
    In addition, the methoxy group of the compound will also affect its properties. Methoxy is a power supply group, which can increase the electron cloud density on the benzene ring through conjugation effect and induction effect, making the benzene ring more prone to electrophilic substitution reaction, and the reaction check point may be specific due to the positioning effect of methoxy group.
    The physicochemical properties of 5-methoxy-1,3-dihydro-2H-imidazolo [4,5-b] pyridine-2-thione are determined by its molecular structure, and these properties lay the foundation for its application in chemistry and related fields.
    What is the price range of 5-methoxy-3-dihydro-2H-imidazo [4,5-b] pyridine-2-thione in the market?
    I don't know if 5-methoxy-1,3-dihydro-2H-imidazolo [4,5-b] pyridine-2-thione is in the market price range. This compound is very familiar, and its price is easily influenced by many factors.
    First, the difficulty of preparation has a great impact. If the preparation requires complex steps, special raw materials or harsh conditions, the cost will be high, and the price will also rise. Second, the amount of market demand is the key. If the demand is strong and the supply is in short supply, the price may rise; if the demand is low, the price may decline. Third, the purity is also a determinant of the price. For high purity, the preparation is difficult and the price will be higher.
    Due to the lack of detailed preparation details, market supply and demand, and common purity, it is difficult to determine its price range. If you want to know the exact price, you can consult chemical reagent suppliers, chemical product trading platforms, or there may be relevant quotations there to obtain accurate price information.