5 Hydroxy 3 Pyridinecarboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

5-hydroxy-3-pyridinecarboxylic acid

    Specifications

    HS Code

    396753

    Name 5-hydroxy-3-pyridinecarboxylic acid
    Molecular Formula C6H5NO3
    Molecular Weight 139.11 g/mol
    Appearance Solid (presumed, no color specified commonly)
    Solubility In Water Moderate solubility (due to polar groups)
    Stability Stable under normal conditions, may be sensitive to strong acids/bases and heat

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 5-hydroxy-3-pyridinecarboxylic acid?
    5-Hydroxy-3-pyridinecarboxylic acid is 5-hydroxy-3-pyridinecarboxylic acid, and its chemical structure is as follows:
    This compound belongs to the pyridine derivative. Pyridine is a six-membered heterocyclic compound containing a nitrogen atom and has aromatic properties. At position 3 of the pyridine ring, a carboxyl group (-COOH) is connected. This carboxyl group is an acidic group, which can exhibit the general chemical properties of carboxylic acids, such as neutralization with bases to form corresponding salts, esterification with alcohols under the action of catalysts, etc. At the 5th position of the pyridine ring, a hydroxyl group (-OH) is connected. The presence of the hydroxyl group makes the compound have certain hydrophilicity. At the same time, the hydroxyl group can also participate in various chemical reactions, such as substitution reactions with other compounds under appropriate conditions. The overall chemical structure of 5-hydroxy-3-pyridinecarboxylic acid endows it with unique physical and chemical properties, and has potential application value in organic synthesis, pharmaceutical chemistry and other fields.
    What are the physical properties of 5-hydroxy-3-pyridinecarboxylic acid?
    5-Hydroxy-3-pyridinecarboxylic acid, also known as 5-hydroxynicotinic acid, is an important organic compound. It has specific physical properties, let me tell them one by one.
    Looking at its properties, under normal temperature and pressure, 5-hydroxy-3-pyridinecarboxylic acid is mostly white to light yellow crystalline powder. This form makes it easy to handle and measure in many chemical operations and applications.
    As for the melting point, it has been accurately determined to be in the range of 220-225 ° C. The characteristics of the melting point are of great significance for distinguishing the authenticity and purity of the compound. The melting point of 5-hydroxy-3-pyridinecarboxylic acid with different purity may be slightly different, which is an important basis for quality testing.
    Solubility is also a key physical property. It is slightly soluble in water, and its solubility is slightly increased in hot water. This characteristic causes its solubility to be greatly affected by temperature in the aqueous reaction system. At the same time, the compound is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), etc. However, in common organic solvents such as ether and petroleum ether, the solubility is poor. Such solubility has far-reaching effects on the separation, purification and choice of reaction medium of the compound. < Br >
    The density of 5-hydroxy-3-pyridinecarboxylic acid, although there is no extremely accurate universal value, is roughly equivalent to the density of common organic solids. Density parameters are indispensable for the calculation of material quantities and equipment design in chemical production.
    In terms of stability, 5-hydroxy-3-pyridinecarboxylic acid is quite stable under normal storage conditions at room temperature. In case of strong acids, strong bases, or extreme conditions of high temperature and high humidity, or chemical reactions occur, resulting in changes in structure and properties.
    In summary, the physical properties of 5-hydroxy-3-pyridinecarboxylic acid have important reference value in many fields such as chemistry, medicine, materials, etc.
    Where is 5-hydroxy-3-pyridinecarboxylic acid used?
    5-Hydroxy-3-pyridinecarboxylic acid, also known as 5-hydroxynicotinic acid, this compound is useful in many fields such as medicine and chemical industry.
    In the field of medicine, it has potential medicinal value. Or it can participate in drug synthesis as a key intermediate to create new drugs. The special structure of the pyridine ring and hydroxyl and carboxyl groups makes the compound have unique chemical and biological activities. It can be used to develop therapeutic drugs for specific diseases through chemical modification and modification, such as for the development of anti-tumor drugs, whose structure may interact with specific targets of tumor cells and interfere with the growth and proliferation of tumor cells; or for the development of drugs for the treatment of nervous system diseases, with its activity affecting neurotransmitter metabolism or nerve cell signaling.
    In the chemical industry, 5-hydroxy-3-pyridinecarboxylic acid can be used as a raw material for organic synthesis. It can participate in a variety of organic reactions and synthesize compounds with special properties. For example, in materials science, through a specific reaction path, polymer materials with specific optical, electrical or mechanical properties are synthesized, which are used to prepare new optoelectronic materials, endow the materials with unique optical properties, and can be used in display screens, Light Emitting Diodes and other devices. It can also be used to prepare high-performance engineering plastics to improve the mechanical properties and chemical stability of plastics.
    In addition, in the agricultural field, it can be used as a raw material for pesticides or plant growth regulators. With its chemical structure properties, products that can control pests and diseases or promote plant growth can be developed, providing assistance for agricultural production.
    What are the synthetic methods of 5-hydroxy-3-pyridinecarboxylic acid?
    5-Hydroxy-3-pyridinecarboxylic acid, also known as 5-hydroxynicotinic acid, is a method for the synthesis of this substance. It is rarely published in ancient books. However, after many studies by various scholars in this world, there are several methods to follow.
    One is a method of chemical synthesis. Pyridine is used as the initial material and is formed through a multi-step reaction. First, pyridine is substituted with a suitable reagent under specific conditions, and a carboxyl group is introduced into it at 3 positions. This step requires careful temperature control, appropriate catalyst and reaction solvent selection, and the reaction is carried out in the desired direction. Then hydroxyl groups are introduced at 5 positions. This process may involve several steps such as oxidation and reduction. Each step requires fine operation to maintain the purity and yield of the product.
    The second can be obtained by biosynthesis. Using the catalytic properties of microorganisms or enzymes, specific precursor substances are used as substrates. If microorganisms with specific metabolic pathways are selected, under suitable culture conditions, the enzyme system in their bodies can be converted to the substrate. This process requires optimizing the culture conditions, such as temperature, pH value, nutrients, etc., so that the microorganisms or enzymes exhibit the best activity, thereby increasing the production of 5-hydroxy-3-pyridinecarboxylic acid.
    Third, natural products are also used as starting materials, which are extracted and converted. There are some plants or microorganisms in nature that contain substances with similar structures. First, these substances are extracted from natural sources, and then they are gradually converted into 5-hydroxy-3-pyridinecarboxylic acid by means of chemical modification. The key to this approach lies in the acquisition of natural raw materials and the establishment of efficient conversion methods.
    The above methods have advantages and disadvantages. Although the steps of chemical synthesis are complex, they are highly controllable. Biosynthesis is green and environmentally friendly, but it requires strict conditions. The method of using natural products as the source may have unique advantages in raw materials, but it may be difficult to obtain raw materials. All kinds of synthetic methods are constantly exploring and improving to obtain this substance.
    What is the market outlook for 5-hydroxy-3-pyridinecarboxylic acid?
    5-Hydroxy-3-pyridinecarboxylic acid, its market prospects are worth exploring in this world. This substance is useful in the fields of chemical medicine.
    In the pharmaceutical industry, because of its unique chemical structure, it may be used as a key intermediate in drug synthesis. Looking at the current trend of pharmaceutical research and development, there is a growing demand for novel and active compounds. 5-Hydroxy-3-pyridinecarboxylic acid may provide new opportunities for the creation of innovative drugs. Many pharmaceutical companies are looking for such characteristic raw materials to develop good drugs for the treatment of difficult diseases. Therefore, from the perspective of medicine, its market prospect is like the rising sun, with huge potential.
    In the chemical industry, it can participate in the preparation of a variety of fine chemicals. As the chemical industry moves towards high-end and fine direction, the quality and output requirements for such compounds are also rising. Many fine chemical companies are actively expanding their product lines, and 5-hydroxy-3-pyridinecarboxylic acid may be the focus of their attention. Because it can improve product performance and enhance the competitiveness of chemical products.
    However, its market development is not smooth sailing. Optimization of production processes and effective control of costs are all key. If a breakthrough can be made in this regard, its market share will expand steadily, and it will occupy an important position in the chemical and pharmaceutical market. The future will be bright, like stars shining in the night sky.