5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

5 - fluoro - 1 - (2 - fluorobenzyl) - 1H - pyrazolo [3,4 - b] pyridine - 3 - carbonitrile is an organic compound. Its main uses can be found in the field of medicinal chemistry.
In the process of drug development, many compounds can exhibit biological activity due to their unique chemical structures and properties. This compound may have the potential to interact with specific biological targets, such as binding to certain protein kinases. Protein kinases play a key role in cell signaling pathways. Once abnormal, they are often closely related to the occurrence and development of diseases, especially cancer.
For example, in the exploration of cancer therapeutic drugs, researchers are committed to finding compounds that can precisely inhibit the activity of specific kinases. If this compound can selectively inhibit some cancer-promoting kinases, it may hinder the proliferation, invasion and metastasis of cancer cells, providing new opportunities for cancer treatment.
Furthermore, in the development of drugs for neurological diseases, it may interact with neurotransmitter-related targets and regulate neural signaling, which may be beneficial for the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
In addition, in the field of agricultural chemistry, compounds with similar structures may have insecticidal and bactericidal activities, or can be used to develop new pesticides to help control crop diseases and insect pests and improve agricultural production efficiency. < Br >
However, it needs to be understood that although this compound has potential application value, its practical use still needs to be strictly verified by a large number of experimental studies, such as in vitro cell experiments, animal experiments and even clinical trials, in order to clarify its safety and effectiveness, and then realize its practical application in medicine, agriculture and other fields.

5 - fluoro - 1 - (2 - fluorobenzyl) - 1H - pyrazolo [3,4 - b] pyridine - 3 - carbonitrile is an organic compound, and there are many methods for synthesizing this compound.
The first method is to take an appropriate pyridine derivative, introduce a cyanyl group with a specific reagent, and then under suitable conditions, cyclize to construct the skeleton of pyrazole and pyridine. When cyclization, a suitable base and reaction temperature should be selected to ensure the smooth progress of the reaction and good selectivity. < Br >
Another method can start from fluorine-containing benzaldehyde, and react with cyanoacetamide through condensation reaction to form key intermediates. After that, the intermediate undergoes molecular cyclization under the catalysis of acid or base, forming the basic structure of the target, and introducing fluorine atoms at specific positions.
Another synthesis method is to react 2-fluorobenzyl halide with the active intermediate containing nitrogen heterocyclic ring to form a carbon-nitrogen bond, and then further modify it to introduce cyanyl and fluorine atoms at specific positions of the pyrazole-pyridine ring. In this process, the choice of reaction solvent and catalyst is quite important, which is related to the reaction rate and product purity.
All synthesis methods have advantages and disadvantages. Although the reaction steps are short, the raw materials are rare or the reaction conditions are harsh; although the raw materials are easy to obtain, the steps are complicated and require multiple steps of reaction and purification of intermediate products. When synthesizing, it is necessary to comprehensively consider many factors such as raw material cost, reaction conditions, yield and purity, and choose the optimal method to achieve the high-efficiency synthesis of 5-fluoro-1 - (2 - fluorobenzyl) - 1H - pyrazolo [3,4 - b] pyridine - 3 - carbonitrile.

5 - fluoro - 1 - (2 - fluorobenzyl) - 1H - pyrazolo [3,4 - b] pyridine - 3 - carbonitrile is an organic compound. The physical and chemical properties of this compound depend on its many properties.
Its appearance may be solid, and the color is mostly white to off-white powder. In terms of melting point, or in a specific temperature range, the specific value varies depending on factors such as preparation purity. Generally speaking, its melting point helps to identify and distinguish this compound. < Br >
In terms of solubility, it may have certain solubility in common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., but it has poor solubility in water. This characteristic is due to the large proportion of hydrophobicity in its molecular structure.
Stability is also an important property. Under normal temperature and pressure and dry environment, this compound is relatively stable. However, it encounters strong oxidizing agents, strong acids and bases, etc., or chemical reactions occur, causing its structure to change. Under light conditions, its photostability also needs to be considered, because some groups in its structure may be sensitive to light, triggering photochemical reactions.
From the perspective of spectral properties, its infrared spectrum can exhibit characteristic absorption peaks, which are related to various chemical bonds in molecules, such as the stretching vibration absorption peaks of cyanide groups, which can provide strong evidence for structure identification. Nuclear magnetic resonance spectroscopy, whether hydrogen spectroscopy or carbon spectroscopy, can reveal the information of hydrogen and carbon atoms in different chemical environments in molecules, helping to determine the molecular structure and purity analysis.
The above physical and chemical properties play a key role in the application of this compound in organic synthesis, drug development and other fields, and help researchers understand its behavior and reaction characteristics.

5 - fluoro - 1 - (2 - fluorobenzyl) - 1H - pyrazolo [3,4 - b] pyridine - 3 - carbonitrile is an organic compound, and its market price range varies due to a variety of factors, which is difficult to determine.
This compound is very common in general-purpose chemicals. Its synthesis steps may be more complex, and specific reaction conditions and technologies are required, which has a great impact on the price. If the preparation requires multi-step reactions, expensive reagents or harsh conditions, the cost will be high, and the price will also increase.
Purity is another key factor. High-purity products are more expensive because they require finer purification processes, which take more time and resources. Research-grade high-purity products, the price may far exceed that of industrial-grade lower purity products.
The market supply and demand relationship also affects the price. If there is a large increase in demand for many industries or research projects at a certain time, and the supply is limited, the price will rise; conversely, if there is less demand and more supply, the price may fall.
In addition, different suppliers have different pricing strategies, and the purchase volume is different, and the price is also different. Usually, large purchases can enjoy discounts.
Due to the combined effect of the above factors, the price of 5 - fluoro - 1 - (2 - fluorobenzyl) - 1H - pyrazolo [3,4 - b] pyridine - 3 - carbonitrile fluctuates widely, and it is difficult to determine the specific price range. If you need the exact price, you should consult the relevant chemical product supplier or market platform.

5 - fluoro - 1 - (2 - fluorobenzyl) - 1H - pyrazolo [3,4 - b] pyridine - 3 - carbonitrile is an organic compound with many related patents. This compound has a wide range of uses in the field of medicinal chemistry, especially in the development of new drugs. Due to its unique chemical structure, or specific biological activities and pharmacological effects, it has attracted the attention of many researchers and pharmaceutical companies, which has led to many related patents.
In the field of anti-cancer drug research and development, there is a patent to explore its inhibitory effect on specific cancer cells. Studies have found that the compound may precisely act on specific targets of cancer cells, block the proliferation of cancer cells, and induce their apoptosis. This type of patent multi-focus optimizes the structure of the compound, improves the anti-cancer activity and selectivity, and reduces the toxic side effects on normal cells. For example, by modifying the substituents on the benzene ring or pyrazolopyridine structure, the physicochemical properties and biological activities of the compound are changed, and new anti-cancer drugs with high efficiency and low toxicity are developed.
In the field of anti-inflammatory drugs, there are also related patents. Studies have shown that this compound may regulate inflammation-related signaling pathways, inhibit the release of inflammatory mediators, and demonstrate anti-inflammatory potential. The patent content may involve screening suitable dosage forms and routes of administration to improve the bioavailability and efficacy of the compound. Like preparing nanoparticle dosage forms to improve their solubility and distribution in vivo, and enhance anti-inflammatory effects.
Some patents also Traditional synthesis routes or steps are cumbersome, low yield, and high environmental pollution. The new patent is dedicated to the development of simple, efficient, and environmentally friendly synthesis processes. For example, using new catalysts or reaction conditions to shorten reaction steps and increase yield while reducing negative environmental impact provides a feasible solution for large-scale production.