5 Ethylpyridine 2 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

5-ethylpyridine-2-carboxylic acid

    Specifications

    HS Code

    606396

    Chemical Formula C8H9NO2
    Molar Mass 151.16 g/mol
    Appearance Solid (likely white or off - white)
    Solubility In Water Low solubility, as pyridine - carboxylic acids are generally sparingly soluble in water
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Pka Value The carboxylic acid group likely has a pKa around 4 - 5 (estimated based on similar carboxylic acids)

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    General Information
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    Frequently Asked Questions

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    What is the chemistry of 5-ethylpyridine-2-carboxylic acid?
    5-Ethylpyridine-2-carboxylic acid is 5-ethylpyridine-2-carboxylic acid. This is an organic compound. It has specific chemical properties, so let me tell you one by one.
    In terms of physical properties, this compound is mostly solid under normal conditions. However, due to the characteristics of the intramolecular structure, its melting point and boiling point are affected by intermolecular forces. The presence of pyridine rings, carboxyl groups and ethyl groups in the molecule can form hydrogen bonds, van der Waals forces and other forces between molecules. Generally speaking, the presence of carboxyl groups can enhance intermolecular hydrogen bonds, and the melting point is increased.
    In terms of chemical properties, the activity of carboxyl groups is significant. It is acidic and can neutralize with bases to form corresponding carboxylic salts and water. This reaction is based on the fact that the carboxyl group can ionize hydrogen ions. If reacted with sodium hydroxide, the hydrogen ion in the carboxyl group combines with the hydroxide ion to form water, resulting in 5-ethylpyridine-2-carboxylate sodium salt.
    Furthermore, the pyridine ring also gives the compound unique reactivity. The pyridine ring has certain aromatic and basic properties, and can undergo electrophilic substitution reaction with electrophilic reagents. Due to the electron-absorbing effect of the nitrogen atom on the pyridine ring, the electron cloud density on the ring is uneven, and the substitution reaction mostly occurs in the position where the electron cloud density is relatively high. As an alkyl group, ethyl can undergo some common alkyl reactions, such as halogenation reactions under appropriate conditions.
    In addition, the various groups in the molecule of the compound interact with each other, such as the influence of ethyl on the electron cloud distribution of the pyridine ring, which in turn affects the electrophilic substitution activity of the pyridine ring; there is also electronic effect transfer between the pyridine ring and the carboxyl group, which affects the acidity of the carboxyl group. These many chemical properties make it have great application potential in organic synthesis and other fields.
    What are the main uses of 5-ethylpyridine-2-carboxylic acid?
    5-Ethylpyridine-2-carboxylic acid, that is, 5-ethylpyridine-2-carboxylic acid, has a wide range of uses. In the field of medicine, it is an important organic synthesis intermediate and can be used to create a variety of drugs. For example, in the synthesis of some antibacterial drugs, 5-ethylpyridine-2-carboxylic acid can be used to construct a drug activity structure through specific reaction steps to enhance the targeting and effectiveness of drugs against pathogens.
    In the field of materials science, it can participate in the preparation of functional materials. By polymerizing or modifying with other compounds, it gives materials special properties. For example, the preparation of polymer materials with adsorption or identification functions for specific substances has potential applications in environmental monitoring and substance separation.
    In organic synthesis chemistry, 5-ethylpyridine-2-carboxylic acid can participate in many reactions due to its unique chemical structure, such as esterification reaction, amidation reaction, etc. With the help of these reactions, more complex and diverse organic compounds can be synthesized, providing more possibilities and options for the development of organic synthesis chemistry.
    In addition, in the dye industry, it may be used as a raw material to participate in the synthesis of certain dyes, giving specific colors and properties to dyes, and improving the quality and application range of dyes. Overall, 5-ethylpyridine-2-carboxylic acid plays an indispensable role in many fields and plays an important role in promoting the development of related industries.
    What are the synthetic methods of 5-ethylpyridine-2-carboxylic acid?
    5-Ethylpyridine-2-carboxylic acid, or 5-ethylpyridine-2-carboxylic acid, can be synthesized in a variety of ways. One common starting material is 2-methyl-5-ethylpyridine. This starting material and suitable oxidants, such as potassium permanganate ($KMnO_4 $) or potassium dichromate ($K_2Cr_2O_7 $), etc. Under suitable reaction conditions, such as in an acidic medium and heated environment, methyl groups can be oxidized to carboxyl groups, and then the target product 5-ethylpyridine-2-carboxylic acid can be formed.
    Another method can be started from 2-cyano-5-ethylpyridine. By hydrolysis under acidic or alkaline conditions, the cyano group can be converted to carboxyl groups, so as to achieve the synthesis of 5-ethylpyridine-2-carboxylic acid. In acidic hydrolysis, strong acids such as sulfuric acid ($H_2SO_4 $) are generally used; in alkaline hydrolysis, strong bases such as sodium hydroxide ($NaOH $) are often used, and then acidified to obtain the product. < Br >
    Pyridine-2,5-dicarboxylic acid can also be used as a raw material. The 5-carboxyl group is properly protected first, and the 2-carboxyl group is then reduced to transform the carboxyl group into other groups that can be further reacted. Then ethyl is introduced, and finally the protective group is removed to obtain 5-ethylpyridine-2-carboxylic acid.
    These synthesis methods have their own advantages and disadvantages, and the most suitable synthesis path should be selected according to actual needs, such as the availability of raw materials, the ease of operation of reaction conditions, and the purity requirements of the product.
    What is the market price of 5-ethylpyridine-2-carboxylic acid?
    In today's world, there are many commercial roads, and it is not easy to know the price of 5-ethylpyridine-2-carboxylic acid in the market. This compound may be used in various fields of medicine and chemical industry, and its price changes depend on many factors such as supply and demand, production method, and quality.
    Looking at the chemical industry in the past, the price of materials often moved according to the times. If there are many people who need this product, but there are few producers, the price will rise; if there are many products, but few people who want it, the price will be depressed. The production method is also the main reason. If there is a convenient and efficient method, the cost will drop, and the price may drop; on the contrary, if the system is difficult and expensive, the price will be high.
    Furthermore, quality is related to the price. Those with high purity and few impurities must be better than those with inferior prices. However, the price of the market cannot be generalized, and the price varies from place to place due to trade, tax and logistics.
    To get an accurate price, you should consult chemical material suppliers, trading platforms, or refer to industry reports and market surveys. In this way, you can get the current price of 5-ethylpyridine-2-carboxylic acid in order to deal with the business.
    What are the precautions for 5-ethylpyridine-2-carboxylic acid in storage and transportation?
    5-Ethylpyridine-2-carboxylic acid is an organic compound. During storage and transportation, many matters need to be paid careful attention.
    First storage environment. This compound should be stored in a cool, dry and well-ventilated place. Because it is sensitive to temperature and humidity, high temperature and humid environment are prone to deterioration. If the temperature of the storage place is too high, it may cause changes in the molecular structure of the compound, which will damage its chemical stability; if the humidity is too high, it may also promote reactions such as hydrolysis. Therefore, the storage temperature should be maintained at a specific low temperature range, such as 5 to 25 degrees Celsius, and the relative humidity should be controlled at 40% to 60%.
    The second is the packaging requirement. Be sure to use well-sealed packaging materials to prevent contact with air, moisture, etc. Common packaging materials such as glass bottles, plastic bottles, or metal containers lined with special materials. Glass bottles have good chemical stability and can effectively block the intrusion of external substances; plastic bottles are lightweight and have certain anti-leakage properties, but it is necessary to ensure that their materials do not react with compounds; although metal containers are strong, they need to be lined with suitable materials to prevent metal and compounds from reacting chemically. On the packaging container, key information such as the name, specifications, and storage conditions of the compound should be clearly marked.
    The transportation process is also critical. During transportation, severe vibration and collision should be avoided. The structure of this compound may be damaged due to vibration and collision. It is advisable to choose a smooth transportation method, such as road transportation with good shock absorption performance vehicles, and railway transportation to ensure stable carriages. At the same time, the temperature and humidity of the transportation environment should also be strictly controlled, and transportation equipment with temperature control and humidity control functions can be used to maintain suitable storage conditions. Transport personnel also need to have professional knowledge, familiar with compound properties and emergency treatment methods, and can quickly and properly deal with emergencies such as leaks.