As a leading 5-ethyl-2-[4-methyl-5-oxo-4-(propan-2-yl)-4,5-dihydro-1H-imidazol-2-yl]pyridine-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 5-ethyl-2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] pyridine-3-carboxylic acid
The Chinese name of this compound is 5-ethyl-2- [4-methyl-5-oxo-4- (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] pyridine-3-carboxylic acid. Its chemical structure can be explained as follows:
1. ** Pyridine ring core **: The pyridine ring is the basic skeleton of this compound, like the beam of a pavilion, supporting the entire molecular structure. There are specific substituents on the pyridine ring, and the third position is connected to the carboxyl group (-COOH). This carboxyl group often has acidic characteristics in organic reactions and can participate in many acid-base reactions and ester reactions. Just like the specific decoration of the pavilion, it gives the molecule unique reactivity. The introduction of ethyl at the 5th position is connected to ethyl (-CH ² CH 🥰). The introduction of ethyl will affect the lipophilicity of the molecule, making the molecule have different solubility in different solvents, which is like adding a different style of decoration to the pavilion, affecting its interaction with the external environment.
2. ** Imidazole ring substituent **: The second position of the pyridine ring is connected to the imidazole ring derivative. The imidazole ring has undergone 4,5-dihydrogen modification, that is, the double bonds at the 4,5 positions are reduced. The fourth position is methyl (-CH) and isopropyl (-CH (CH) -2), and the fifth position is carbonyl (C = O). The imidazole ring is common in many bioactive molecules, and this structure gives the compound the potential to interact with biological macromolecules, such as binding to protein-specific check points, like a mysterious channel hidden in a pavilion, which can be connected to specific objects in the outside world to exert physiological activity.
In summary, the chemical structure of 5-ethyl-2- [4-methyl-5-oxo-4- (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] pyridine-3-carboxylic acid is based on the pyridine ring, with specific position substituents and imidazole ring derivatives, and the parts cooperate with each other to endow the compounds with unique physical and chemical properties and potential biological activities.
What are the main uses of 5-ethyl-2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] pyridine-3-carboxylic acid
5-Ethyl-2- [4-methyl-5-oxo-4- (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] pyridine-3-carboxylic acid, this is an organic compound. Its main uses are complex, let me tell you one by one.
In the field of medicinal chemistry, such compounds often have potential biological activities. Or can be used as lead compounds, which have been deeply studied and optimized to create new drugs. Because their structure is rich in specific functional groups, or can interact with targets in organisms, such as specific enzymes, receptors and the like. Through this interaction, the physiological and biochemical processes in the organism can be modulated to exert therapeutic effects on diseases. For example, it may exhibit anti-inflammatory activity against certain inflammation-related targets; or it may exhibit anti-tumor activity against specific receptors of tumor cells.
In the field of materials science, such compounds may be used as building blocks of functional materials. Due to their structural properties, they may endow materials with unique optical and electrical properties. For example, they may be used to prepare organic Light Emitting Diode (OLED) materials. With their molecular structure and electronic properties, they can achieve high-efficiency luminescence and improve the luminous efficiency and color purity of OLED devices.
Furthermore, in the field of organic synthetic chemistry, this compound can be used as a key intermediate. By virtue of the various active checking points in its structure, a series of compounds with more complex structures can be derived through various organic reactions. It provides the possibility for organic synthesis chemists to expand the compound library and promote the development of organic synthesis methodologies. Such as condensation and substitution reactions with other compounds containing active groups to create new structural compounds.
What is the synthesis method of 5-ethyl-2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] pyridine-3-carboxylic acid
To prepare 5 - ethyl - 2 - [4 - methyl - 5 - oxo - 4 - (propan - 2 - yl) -4,5 - dihydro - 1H - imidazol - 2 - yl] pyridine - 3 - carboxylic acid, the following ancient method can be followed.
Take the appropriate pyridine derivative first, and its structure needs to contain a modifiable check point to facilitate subsequent reactions. The pyridine derivative is placed in a suitable reaction vessel, supplemented with an organic solvent, such as dichloromethane or N, N-dimethylformamide, to fully dissolve the substrate and create a homogeneous reaction environment.
In this solution, slowly add a specific imidazole derivative, which should have 4-methyl-5-oxo-4- (propan-2-yl) -4,5-dihydro-1H-imidazol-2-yl structural part. When adding, pay attention to temperature control, often maintain at low temperature, such as between 0 ° C and 5 ° C, to prevent side reactions. After adding imidazole derivatives, an appropriate amount of base, such as triethylamine or potassium carbonate, can be dropped to catalyze the reaction. The amount of base should be carefully determined according to the amount of substrate and the scale of the reaction.
When reacting, it is often stirred to help it mix thoroughly. After a certain period of time, or even a few days, depending on the reaction process, the degree of reaction should be monitored by thin-layer chromatography or high-performance liquid chromatography. When the reaction reaches the desired level, quench the reaction with an acid solution such as dilute hydrochloric acid, and adjust the pH of the reaction solution to a weakly acidic state.
Then, the extraction method is performed, and the product is extracted with an organic solvent such as ethyl acetate. After several extractions, the organic phases are combined and dried with anhydrous sodium sulfate to remove the moisture in the organic phase.
After that, the organic solvent is removed by reduced pressure distillation to obtain the crude product. Then it is refined by column chromatography or recrystallization, and a suitable eluent or solvent is selected to obtain a pure 5-ethyl-2- [4-methyl-5-oxo-4- (propan-2-yl) -4,5-dihydro-1H-imidazol-2-yl] pyridine-3-carboxylic acid product. During the whole process, the control of the reaction conditions and the care of each step are the keys to obtaining the pure product.
What are the physical properties of 5-ethyl-2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] pyridine-3-carboxylic acid
5-Ethyl-2 - [4-methyl-5-oxo-4 - (isopropyl) -4,5-dihydro-1H-imidazole-2-yl] pyridine-3-carboxylic acid, this compound has some unique physical properties. Its appearance is often white to off-white crystalline powder, which is easy to observe and handle. In many experiments and production links, this appearance feature is conducive to its resolution and operation.
In terms of solubility, it has a certain performance in organic solvents. In common organic solvents such as dichloromethane and N, N-dimethylformamide, it exhibits moderate solubility. In dichloromethane, with the increase of temperature, the dissolution rate is accelerated, and the solubility is also improved. This property has a profound impact on the reaction or separation operation carried out with dichloromethane as a solvent, which is related to the smooth development of the reaction and the effectiveness of product separation. In N, N-dimethylformamide, the solution formed after dissolution is quite stable, creating good conditions for homogeneous reactions involving this compound.
However, in water, the solubility of this compound is very small. Due to the large proportion of hydrophobic groups in its molecular structure, such as ethyl, isopropyl, etc., the force between these groups and water molecules is weak, making it difficult to dissolve in water. This characteristic determines its limited application in aqueous systems. When designing related experiments or processes, it is necessary to avoid the system with water as a single solvent, or add specific additives to improve its affinity with water. In terms of the melting point of
, after accurate determination, the melting point of the compound is in a specific range, which is of great significance for the identification of the purity of the compound. If the purity is high, the melting point range is relatively narrow and close to the theoretical value; if it contains impurities, the melting point will be reduced and the melting range will become wider. Therefore, melting point measurement has become one of the important means to detect the purity of the compound.
5-Ethyl-2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] pyridine-3-carboxylic acid market prospects
Today there is a compound called 5-ethyl-2- [4-methyl-5-oxo-4- (propan-2-yl) -4, 5-dihydro-1H-imidazol-2-yl] pyridine-3-carboxylic acid. Looking at its market prospects, it is like a changing situation, and there is no shortage of opportunities to explore.
This compound may have unique potential in the field of scientific research. In the process of organic synthesis, it can serve as a key intermediate, paving the way for the creation of novel organic molecules. If chemists can make good use of its characteristics and carefully design reactions, it may give rise to many unprecedented compounds, injecting new springs into the fields of materials science, drug development and other fields.
When it comes to drug research and development, its prospects may be hidden in the clouds. The unique structure may give it the possibility to interact with specific biological targets. If pharmacologists can carefully explore its activity, it may open the door to a new class of drugs. However, the road of research and development is full of thorns, and it needs to go through many experiments and verifications. From cell experiments to animal experiments to clinical trials, it needs to be rigorous in order to determine its efficacy and safety.
In materials science, it may be transformed and become the cornerstone of building materials with special properties. Its structure may endow the material with unique electrical, optical or mechanical properties, illuminating hope for the preparation of high-performance functional materials. However, the expansion of material applications also needs to overcome problems such as cost control and large-scale preparation process optimization.
However, the market prospect is not entirely bright. The synthesis process of this compound may be complicated and the cost may remain high, limiting its large-scale application. And the market competition is like a thousand sails racing, with similar or alternative compounds emerging in an endless stream. If it cannot stand out, it may be difficult to gain a place.
To sum up, the market prospects of 5-ethyl-2 - [4-methyl-5-oxo-4 - (propan-2-yl) -4,5-dihydro-1H-imidazol-2 - yl] pyridine-3 - carboxylic acid, opportunities and challenges stand side by side. It takes scientific researchers and entrepreneurs from all parties to work together with wisdom and efforts to clear the clouds and see its bright future.