As a leading 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 5-ethyl-2- [2- (4-nitrophenoxy) ethyl] pyridine
This is the name of the organic compound, and its chemical structure can be known according to this name. "5-ethyl-2 - [2 - (4 - nitrophenoxy) ethyl] pyridine", "5-ethyl" indicates that the pyridine ring has an ethyl substitution at position 5. Ethyl, - C 2O H Also. "2 - [2 - (4 - nitrophenoxy) ethyl]" indicates that the second position of the pyridine ring is connected to a side chain containing a specific structure. In this side chain, there is first "2 - (4 - nitrophenoxy) ethyl", that is, 2 - (4 - nitrophenoxy) ethyl. In the case of 4-nitrophenoxy, the benzene ring has a nitro group (-NO -2) at position 4, and is connected to ethyl through an oxygen atom. The phenoxy group is -O-phenyl, and the phenyl group is the phenyl ring to remove a hydrogen atom remaining part. Ethyl is attached to the end of the side chain at position 2 of the pyridine ring to form this complex organic structure.
In summary, the chemical structure of the compound is centered on the pyridine ring, with ethyl at position 5 and side chain containing 2- (4-nitrophenoxy) ethyl at position 2. This structure has the characteristics of the pyridine ring, and it presents unique chemical properties due to the introduction of substituents. The structure of nitro and phenoxy on the side chain will affect its physical and chemical behavior, such as solubility and reactivity.
What are the physical properties of 5-ethyl-2- [2- (4-nitrophenoxy) ethyl] pyridine
5 - ethyl - 2 - [2 - (4 - nitrophenoxy) ethyl] pyridine is an organic compound. Its physical properties are crucial and have a profound impact on its application in various fields.
The properties of this compound are mostly solid under normal conditions, and the appearance may be crystalline solid, and it has a specific crystal structure. This crystal structure has a great influence on many of its physical properties, such as its response to light and heat. In terms of color, it may be colorless to light yellow, and this color characteristic may be related to the conjugated system and substituents in its molecular structure.
Its melting point is also one of the important physical properties. The specific melting point value can be obtained by experimental determination, which is of great significance for the phase change of the compound under a specific temperature environment. When the temperature rises to the melting point, the compound melts from a solid state to a liquid state. The determination of the boiling point can help to clarify the temperature at which it will change from a liquid state to a gas state. Knowing the boiling point is of great significance in chemical operations such as distillation and separation.
In terms of solubility, the performance of organic solvents is worthy of attention. In common organic solvents such as ethanol and acetone, it may exhibit good solubility. Due to the interaction forces between the molecular structure of the compound and the molecules of the organic solvent, such as van der Waals force, hydrogen bond, etc., the two can be miscible with each other. However, in water, or the solubility is poor, because of its molecular structure, hydrophobic groups account for a large proportion, and the interaction with water molecules is weak.
In addition, density is also one of its physical properties. By accurate measurement, the mass of the compound per unit volume can be obtained. This value has important reference value in practical application scenarios such as material mixing and storage.
The physical properties of this compound, whether it is appearance, melting point, boiling point, solubility or density, are all interrelated and affect its application in different fields. It is an indispensable consideration for the study and application of this compound.
What is the synthesis method of 5-ethyl-2- [2- (4-nitrophenoxy) ethyl] pyridine
5 - ethyl - 2 - [2 - (4 - nitrophenoxy) ethyl] pyridine is also a compound. The synthesis method thereof is described in more detail.
The first one can be started from the pyridine derivative of. With the mother nucleus of pyridine, from the alkylation inverse, 5-ethyl group is introduced. This alkylation method, or can be, such as oxidized, etc., in the solution of, such as N, N - dimethylmethylamine (DMF), 5 - generation ethylpyridine inverse, can be 5 - ethylpyridine derivatives.
Second, to introduce 2 - [2 - (4 - nitrophenoxy) ethyl] group. First, 4 - nitrophenol is substituted for ethanol, such as bromoethanol, in the presence of an organic component, such as carbonate, in an appropriate solution, such as acetonitrile, to generate 4 - nitrophenoxyethanol. In this reverse process, the nuclear substitution of the phenol group is reversed.
The resulting 4-nitrophenoxyethanol is reversed by the aforementioned 5-ethylpyridine derivative. In this step, or in the presence of catalysts, such as iodide, and carbon dioxide, such as carbonate, in the presence of reflux components, acetonitrile or DMF are dissolved, and the nucleus is substituted for the inverse, so that the 2 - [2 - (4 - nitrophenoxy) ethyl] group is successfully connected to the 2-position of pyridine, and then 5 - ethyl - 2 - [2 - (4 - nitrophenoxy) ethyl] pyridine is obtained.
During the synthesis process, attention should be paid to the control of the inverse components, such as the degree of resistance, the amount of resistance, etc. High or inverse resistance may cause side reactions; the difference in the dosage will also affect the rate. And the efficiency of the solution is also very important. It is necessary to conform to the characteristics of each step in order to promote the anti-profit and improve the yield of the product.
What is the main use of 5-ethyl-2- [2- (4-nitrophenoxy) ethyl] pyridine?
5 - ethyl - 2 - [2 - (4 - nitrophenoxy) ethyl] pyridine is one of the organic compounds. Its main use involves the field of organic synthesis and medicinal chemistry.
In the process of organic synthesis, this compound often acts as a key intermediate. Due to its structure of pyridine ring and nitrophenoxyethyl group, it gives it unique reactivity. It can combine with other reagents through nucleophilic substitution, coupling and many other reactions to construct more complex organic molecular structures. For example, the nitrogen atom of the pyridine ring has lone pairs of electrons, which can undergo nucleophilic substitution reactions with halogenated hydrocarbons, introducing different functional groups, paving the way for the subsequent synthesis of multiple and specific organic structures.
In the field of pharmaceutical chemistry, such compounds containing nitrogen heterocycles and phenoxy structures often have potential biological activities. Studies or studies have shown that they may interact with specific targets in organisms, such as specific enzymes or receptors. For example, some compounds containing pyridine structures can exhibit pharmacological properties such as antibacterial and anti-inflammatory properties, while the presence of nitrophenoxy groups may regulate the physical and chemical properties of compounds such as lipid solubility and electron cloud distribution, thereby optimizing their bioavailability and pharmacological activities. Therefore, in the process of new drug development, 5-ethyl-2 - [2 - (4 - nitrophenoxy) ethyl] pyridine may provide an important structural template and idea for the discovery and optimization of lead compounds.
What are the safety precautions for 5-ethyl-2- [2- (4-nitrophenoxy) ethyl] pyridine
5 - ethyl - 2 - [2 - (4 - nitrophenoxy) ethyl] pyridine is an organic compound and should be treated with caution due to its safety precautions.
If this product accidentally touches the skin, or causes skin discomfort, or even causes allergies. Therefore, when operating, be sure to wear protective gloves and protective clothing. If it comes into contact with the skin, rinse with plenty of water immediately, followed by soap.
If splashed into the eyes, it is particularly harmful, or damages eye tissue. At this time, immediately open the eyelids, rinse thoroughly with flowing water or normal saline, and seek medical attention as soon as possible.
If accidentally inhaled, or cause respiratory irritation, causing cough, asthma and other symptoms. The operation should be carried out with good ventilation, or wearing suitable respiratory protective equipment. If inhaled, it should be quickly moved to a fresh air place to keep the respiratory tract unobstructed. If unwell, seek medical attention in time.
Accidentally ingesting this compound may cause damage to the digestive tract. Do not induce vomiting, seek medical attention immediately, and bring the relevant information of this compound to assist doctors in diagnosis and treatment.
In addition, the compound should be properly stored, placed in a cool, dry and well-ventilated place, away from fire and heat sources, and stored separately from oxidants, acids, alkalis, etc. Do not mix storage to avoid dangerous reactions. During the use process, operate strictly according to the specifications, and properly dispose of the residue after use. Do not discard it at will to avoid polluting the environment. Only by treating with caution and strictly adhering to safety regulations can we effectively avoid risks and ensure personal safety and environmental safety.