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What is the chemical structure of 5-ethoxycarbonyl-2-pyridinecarbonitrile?
The chemical structure of 5-ethoxycarbonyl-2-pyridyl methonitrile is as follows:
This compound is based on a pyridine ring, which is a six-membered nitrogen-containing heterocycle and has aromatic properties. In the second position of the pyridine ring, there is a methonitrile group (-CN). In this methonitrile group, the carbon atom and the nitrogen atom are connected by three bonds, and the properties are active. It can participate in many reactions, such as hydrolysis to form carboxylic acids, or addition to nucleophiles.
In the fifth position of the pyridine ring, there is an ethoxycarbonyl group (-COOCH < CH > CH). In the ethoxycarbonyl group, the carbonyl group (C = O) has a strong polarity, and the carbon is partially positively charged, which is vulnerable to nucleophilic attack; while the ethoxy group (-OCH ² CH 🥰) has an impact on the distribution of the carbonyl electron cloud, and the oxygen atom of the ethoxy group also has a certain electronic effect.
Overall, the structure of 5-ethoxycarbonyl-2-pyridineformonitrile, due to the interaction of pyridine ring, methylnitrile and ethoxycarbonyl, endows the compound with unique physical and chemical properties. In the field of organic synthesis, it can be used as a key intermediate to construct more complex organic molecular structures through various reaction pathways.
What are the main uses of 5-ethoxycarbonyl-2-pyridinecarbonitrile?
5-Ethoxycarbonyl-2-pyridylmethonitrile, this is an organic compound with a wide range of uses.
In the field of medicinal chemistry, it is often used as a key intermediate. The synthesis of many drug molecules requires this as the starting material. The special structure of the Gainpyridine ring, ethoxycarbonyl and cyano gives it unique reactivity and biological activity. Through specific chemical reactions, its structure can be modified and modified to meet the design requirements of different drugs, and then compounds with specific pharmacological activities can be synthesized, such as antibacterial, anti-inflammatory, anti-tumor and other drugs.
In the field of materials science, it also has its uses. Due to its structural properties, it can participate in the preparation of some functional materials. For example, it is used to synthesize materials with specific optical and electrical properties. With the functional groups in its molecular structure, it can react with other compounds to construct polymers or composites with special properties, which are used in optical sensors, organic Light Emitting Diodes and other fields.
Furthermore, in organic synthetic chemistry, it is an important class of building blocks. Chemists can use its functional groups to carry out various classical organic reactions, such as nucleophilic substitution reactions, addition reactions, etc., to construct more complex organic molecular structures, expand the structural diversity of organic compounds, and provide a rich material basis and reaction paths for the development of organic synthetic chemistry. In conclusion, 5-ethoxycarbonyl-2-pyridinecarbonitrile plays an indispensable role in many fields such as medicine, materials, and organic synthesis, and is of great significance to promoting scientific research and technological progress in related fields.
What are 5-ethoxycarbonyl-2-pyridinecarbonitrile synthesis methods?
The synthesis method of 5-ethoxycarbonyl-2-pyridyl methonitrile has been around for a long time. In the past, Fang family mostly followed the path of classical organic synthesis. One method is to introduce a halogen atom at a specific position of the pyridine ring through halogenation, and then meet with a cyanylating agent to enter the cyanyl group. Then, through the esterification method, ethanol and an appropriate acylating agent react to obtain ethoxycarbonyl, and finally form this compound.
There is also another method, first introducing a carboxyl group at an appropriate position of the pyridine, and combining an appropriate dehydrating agent with ethanol to form an ethoxycarbonyl group, and then reacting with the cyanide reagent to obtain a cyanyl group, which can also achieve the purpose of synthesis.
There are also nitrogen-containing heterocyclic construction as the beginning, through a series of cyclization and substitution reactions, ethoxycarbonyl and cyanyl groups are gradually introduced. The key here lies in the precise control of the reaction conditions, such as temperature, pH, reaction time and the ratio of reagents, all of which are related to success or failure. If the temperature is too high or too low, the reaction can go astray; if the pH is not correct, the reaction will not be smooth. And after each step of the reaction, fine operation is also required to remove impurities and purify the product to obtain pure 5-ethoxycarbonyl-2-pyridineformonitrile.
What are the physical properties of 5-ethoxycarbonyl-2-pyridinecarbonitrile?
5-Ethoxycarbonyl-2-pyridylmethonitrile is an important compound in the field of organic chemistry. Its physical properties are particularly critical, as follows:
- ** Properties **: Under normal temperature and pressure, this compound is mostly white to light yellow crystalline powder. This morphology is not only easy to observe, but also conducive to handling and quantification in many chemical operations.
- ** Melting point **: about [X] ° C. Melting point, as a characteristic parameter of a substance, is crucial in the identification and purification of this compound. By accurately measuring the melting point, its purity can be determined. If impurities are mixed, the melting point tends to decrease and the melting range becomes wider. < Br > - ** Boiling point **: Under specific pressure conditions, the boiling point is [X] ° C. The boiling point data is indispensable in the separation and purification steps such as distillation, and can be used to set the appropriate temperature to achieve the purpose of effective separation.
- ** Solubility **: It shows good solubility in organic solvents such as ethanol and dichloromethane, but it has little solubility in water. This property is closely related to the molecular structure of the compound. The groups such as ethoxy carbonyl and pyridine ring contain it, which makes it have similar compatibility with organic solvents. This difference in solubility can be used to select suitable solvents for dissolution and extraction in the process of chemical synthesis and product separation. < Br > - ** Density **: The density is about [X] g/cm ³. Density, as an inherent property of matter, has important reference value in experimental operations such as mass and volume conversion and material measurement in industrial production.
What is the price range of 5-ethoxycarbonyl-2-pyridinecarbonitrile in the market?
I have not obtained the exact price of 5 - ethoxycarbonyl - 2 - pyridinecarbonitrile in the market. The price of this compound often varies depending on quality, quantity and supplier.
If you want the price, you can go to the chemical raw material trading platform and chemical reagent supplier. Common such suppliers are Sinopharm Group Chemical Reagent Co., Ltd., search banner reagent company, etc. On the online platform, or see its price.
Generally speaking, the price of a small amount of test dose may be higher due to the cost of preparation, packaging and distribution; if a large amount is purchased, the price per unit may be reduced due to economies of scale.
In addition, its price is also affected by market supply and demand. If there are many people seeking, but there are few products, the price may rise; conversely, if the supply exceeds the demand, the price may decline.
Furthermore, the quality is also related to the price. For high purity, the price is often higher than that of ordinary purity due to difficulty in preparation. Therefore, if you want to know the exact price, you must consult the supplier in detail according to the actual purchase situation.