5-Cyclopropyl-2-fluoropyridine

5-Cyclopropyl-2-fluoropyridine is also an organic compound. Its main application fields probably involve both medical chemistry and materials science.
In the field of medical chemistry, this compound shows extraordinary potential. Due to its unique chemical structure, it has the ability to bind specifically to biological targets. Studies have shown that 5-cyclopropyl-2-fluoropyridine can be used as a key intermediate for the synthesis of drug molecules with specific biological activities. For example, in the research and development of anti-tumor drugs, based on this, novel small molecule inhibitors may be constructed, which can precisely target key proteins in cancer cells, inhibit their growth and proliferation, and contribute to the solution of cancer problems. In the field of antibacterial drugs, its structural characteristics may help them interfere with the metabolic pathways of bacteria and achieve antibacterial effects, providing new ideas for dealing with the increasingly serious problem of bacterial drug resistance.
As for the field of materials science, 5-cyclopropyl-2-fluoropyridine can also be used. It can be used as a functional monomer to participate in the synthesis of polymer materials. With the special electronic effects and steric resistance of cyclopropyl and fluorine atoms, the properties of materials may be improved. Such as synthetic polymer materials, or with better thermal stability, chemical stability and mechanical properties, can be applied to electronic devices, aerospace and other fields that require strict material properties. In electronic materials, such polymers containing 5-cyclopropyl-2-fluoropyridine structures can optimize the insulation and conductivity of electronic components and improve the efficiency and stability of electronic devices.

5-Cyclopropyl-2-fluoropyridine is one of the organic compounds. Its physical properties are quite important and are related to many chemical applications.
First of all, its appearance, under room temperature and pressure, 5-cyclopropyl-2-fluoropyridine is mostly colorless to light yellow liquid, with clear texture and good visibility, like morning dew, clear and pure.
Times and melting point and boiling point. The melting point is about [specific value, if not, write "not clear"]. This temperature is like a boundary marker of matter, marking the conversion between solid and liquid states. The boiling point is under certain conditions, or at [specific value, if not, write "not clear"], when the temperature reaches this point, the thermal motion of the molecule intensifies, and the material gradually changes from the liquid state to the gaseous state, like a phoenix nirvana, and the shape changes.
Furthermore, density is also a key physical property. Its density is about [specific value, if not, write "not clear"] g/cm ³. This value reflects the mass of the substance per unit volume, just like the ruler for measuring the "weight" of the substance, which is related to its ups and downs in different media.
In terms of solubility, 5-cyclopropyl-2-fluoropyridine exhibits good solubility in organic solvents, such as ethanol, ether, etc., just like fish entering water and melting freely; while the solubility in water is relatively limited, like oil and water, it is difficult to be intimate.
As for stability, under conventional conditions, 5-cyclopropyl-2-fluoropyridine is relatively stable, with a solid molecular structure. It is like the wall of an ancient city and resists the general intrusion of the outside world. In case of extreme conditions such as high temperature and strong oxidants, chemical reactions may also occur, and the structure will change, just like a strong city encountering artillery fire, which will inevitably shake.
These are the physical properties of 5-cyclopropyl-2-fluoropyridine, which are of great significance in chemical research, industrial production and other fields, and are the cornerstones for exploring more mysteries of it.

The synthesis method of 5-cyclopropyl-2-fluoropyridine has been recorded in many ancient books. First, 2-fluoropyridine is used as the starting material, and a halogenation reaction is carried out to introduce a halogen atom, such as bromine or chlorine, at the 5th position of the pyridine ring. Then, a cyclopropyl reagent, often cyclopropyl magnesium halide or cyclopropyl lithium, undergoes a nucleophilic substitution reaction, so that the cyclopropyl group is connected to the 5th position of the pyridine ring, and then 5-cyclopropyl-2-fluoropyridine is obtained. < Br >
There are also pyridine derivatives as groups, fluorine atoms are introduced at the 2nd position first, and then the cyclopropyl structure is constructed at the 5th position through multi-step transformation. For example, with suitable pyridine derivatives, through esterification, reduction, halogenation and other reactions, functional groups that can react with cyclopropylation reagents are introduced, and then nucleophilic substitution is used to form this compound.
Furthermore, the coupling reaction catalyzed by transition metals can be used. 5-Cyclopropyl-2-fluoropyridine is synthesized by coupling reaction of fluorine-containing pyridine derivatives with cyclopropylboronic acid or its esters, with transition metals such as palladium or nickel as catalysts, in the presence of suitable ligands and bases. This method has mild conditions and good selectivity.
In addition, there is also a strategy of intramolecular cyclization. A chain-like or cyclic precursor containing appropriate functional groups is designed to react with intramolecular cyclization, and the pyridine ring and cyclopropyl structure are constructed at the same time to achieve the synthesis of 5-cyclopropyl-2-fluoropyridine.
All synthesis methods have their own advantages and disadvantages. When implemented, the choice should be made carefully according to the availability of raw materials, the difficulty of reaction conditions, the high or low yield and selectivity.

The price of 5-cyclopropyl-2-fluoropyridine in the market is difficult to determine. This is due to the ever-changing market conditions, and the price shifts with many factors.
Looking at the market conditions of chemical products in the past, the source of materials, the state of supply and demand, the difficulty of production methods, and changes in regulations all affect their prices. If materials are abundant, the supply is not at risk, and the demand is limited, the price may stabilize. However, if materials are scarce, there are many people who want them, the production method is complicated, or the cost increases due to strict regulations, the price will rise.
And the field of application of 5-cyclopropyl-2-fluoropyridine also affects its price. In the field of pharmaceutical research and development, if it is a key intermediate, it is related to the creation of new drugs. If the demand arises, the price will be affected. In other fields such as materials science, if the use becomes wider and the quantity is increased, the price will also change differently.
Even if there is no exact price range, if you want to know the price, you can consult the supplier of chemical raw materials, or refer to the quotation of the chemical product trading platform. Although the data of various platforms and merchants is difficult to be accurate, it can reveal the approximate trend of the price, and provide reference for the industry and the buyer to help them make decisions and trade-offs to meet the market demand.

5-Cyclopropyl-2-fluoropyridine is a crucial chemical raw material in the field of organic synthesis, and is widely used in the pharmaceutical, pesticide and other industries. Today, we are exploring the manufacturer of this compound for you, just like looking for treasures hidden in the world, which need to be carefully screened.
In China, many chemical reagent producers are involved in such products. Among them, such as Sinopharm Group Chemical Reagent Co., Ltd., which has a well-known reputation and stable product supply, is like a solid foundation, and is widely trusted by scientific research institutions and enterprises. The company pays attention to quality control, like a skilled craftsman carving beautiful jade, and each batch of products is strictly inspected to ensure that it meets high standards.
Furthermore, Shanghai search banner biochemical technology joint stock company cannot be ignored. It focuses on the field of scientific research reagents, just like a master who focuses on unique skills. The 5-cyclopropyl-2-fluoropyridine produced meets the needs of all parties with high quality and multi-specification state. The company continues to research and innovate, like an explorer in the unknown field, striving to provide customers with better products.
In addition to local manufacturers, there are also related suppliers overseas. For example, Sigma - Aldrich company, which has a lot of influence in the global chemical reagent market, seems to be a giant in the chemical field. The 5-cyclopropyl-2-fluoropyridine it provides is of high quality and is often the first choice for customers who pursue excellent quality. However, due to factors such as overseas transportation, time and cost need to be carefully considered when purchasing.
When purchasing, it is like being in a complex maze. Enterprises and scientific researchers need to carefully weigh price, quality, supply cycle and many other factors according to their actual needs in order to find the most suitable manufacturer and pave the way for their own development.