5 Chloro 3 Trifluoromethyl Pyridine 2 Yl Methanol
pyridine pyrrole pyrazine piperidine piperazine

(5-Chloro-3-(trifluoroMethyl)pyridine-2-yl)Methanol

    Specifications

    HS Code

    722294

    Chemical Formula C7H5ClF3NO
    Molecular Weight 213.57
    Appearance Solid (usually white or off - white)
    Solubility In Water Low solubility (organic - like structure)
    Solubility In Organic Solvents Soluble in common organic solvents (e.g., dichloromethane, ethyl acetate)
    Vapor Pressure Low (due to its solid nature, usually)
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

    As an accredited (5-Chloro-3-(trifluoroMethyl)pyridine-2-yl)Methanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive (5-Chloro-3-(trifluoroMethyl)pyridine-2-yl)Methanol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy (5-Chloro-3-(trifluoroMethyl)pyridine-2-yl)Methanol in China?
    As a trusted (5-Chloro-3-(trifluoroMethyl)pyridine-2-yl)Methanol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading (5-Chloro-3-(trifluoroMethyl)pyridine-2-yl)Methanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of (5-chloro-3- (trifluoromethyl) pyridine-2-yl) methanol?
    (5-Hg-3- (triethyl) to its-2-yl) ethane is also an organic compound. Its main uses are as follows:
    First, in the field of organic synthesis, it is an important intermediate. Cover organic synthesis aims to create various organic compounds, while (5-Hg-3- (triethyl) to its-2-yl) ethane can be converted into other organic molecules with specific structures and properties through many chemical reactions. For example, through the substitution reaction, different functional groups can be introduced, and then compounds with special uses can be prepared, such as key intermediates for the synthesis of medicines and pesticides, laying the foundation for the creation of new drugs and pesticides.
    Second, it is also of great significance in materials science. Or it can be used as a starting material for the construction of specific structural polymer materials. By rationally designing the reaction path, it can participate in the polymerization reaction to form polymers with unique properties. These polymers may have excellent mechanical properties, thermal stability or electrical properties, and can be used in many high-end fields such as aerospace and electronic devices to meet the needs of different scenarios for special properties of materials.
    Third, when studying the mechanism of organic reactions, (5-mercury-3- (triethylmethyl) to its -2-yl) ethane can be used as a model compound. Due to its special structure, by observing the chemical reaction processes it participates in, including reaction conditions, product formation, etc., it can gain in-depth insight into the mechanism followed by the reaction, and help chemists understand and predict the trend of organic reactions more accurately, providing important support for the development of organic chemistry theory.
    What are the physical properties of (5-chloro-3- (trifluoromethyl) pyridine-2-yl) methanol
    (5-Deuterium-3- (trifluoromethyl) pyridine-2-yl) acetonitrile is an organic compound widely used in the field of organic synthesis. Its physical properties are as follows:
    - ** Appearance and Properties **: Under normal conditions, it is mostly colorless to light yellow liquid, with a pure and transparent texture. This appearance characteristic is convenient for visual judgment of its state in actual operation, thus ensuring the normal progress of experiments or production processes. < Br > - ** Melting boiling point **: The melting point is low, and the specific value is about -20 ° C according to accurate measurement, which allows the substance to maintain a liquid state in a relatively low temperature environment and exhibit good low-temperature fluidity; the boiling point is relatively high, roughly in the range of 210-220 ° C. The higher boiling point means that under conventional heating conditions, the substance has good thermal stability and is not easy to evaporate and dissipate due to temperature fluctuations, which is conducive to reaction operation and separation and purification in higher temperature environments.
    - ** Solubility **: It exhibits excellent solubility in organic solvents, such as common dichloromethane, chloroform, ether, and N, N-dimethylformamide (DMF). It can be miscible with (5-deuterium-3- (trifluoromethyl) pyridine-2-yl) acetonitrile in any ratio. This excellent solubility provides rich possibilities for the selection of reaction media in the organic synthesis process, and the appropriate solvent system can be flexibly selected according to different reaction requirements to promote the efficient progress of the reaction. However, the solubility of this substance in water is extremely low and almost insoluble. This property is of important guiding significance when it comes to separation operations involving the aqueous phase or the construction of heterogeneous reaction systems. It is helpful to achieve the preliminary separation and purification of the product by simple liquid-liquid separation means.
    - ** Density **: The density is slightly higher than that of water, about 1.3 - 1.4 g/cm ³. This density property makes it possible that in systems involving coexistence with the aqueous phase, (5-deuterium-3- (trifluoromethyl) pyridine-2-yl) acetonitrile will be in the lower layer. This density difference can be conveniently used to achieve separation from the aqueous phase by operations such as liquid separation. < Br > - ** Odor **: It has a special weak irritating odor. Although the odor is not strong, it is still necessary to maintain good ventilation during operation to avoid long-term exposure to prevent adverse effects on the human respiratory tract.
    Is (5-chloro-3- (trifluoromethyl) pyridine-2-yl) methanol chemically stable?
    (5-Cyanogen-3- (trifluoromethyl) pyridine-2-yl) acetonitrile, the chemical properties of this compound are relatively stable.
    The reason is that from the structural point of view, the carbon atom and the nitrogen atom in the cyanyl group (-CN) are connected by a three-bond, and the three-bond energy is quite high. To make it react, a high energy barrier needs to be overcome, which endows the part of the structure with certain stability. As an aromatic heterocyclic structure, the pyridine ring has a stable conjugate system formed by its π electron cloud. This aromatic structure makes the pyridine ring less susceptible to the attack of electrophilic reagents and nucleophiles, thereby enhancing the stability of the whole compound. In trifluoromethyl (-CF), the fluorine atom is extremely electronegative, which will produce a strong electron-absorbing induction effect on the atoms connected to it. Although this effect will affect the distribution of electron clouds on the pyridine ring, it enhances the stability of the molecular structure to a certain extent. In addition, the electronic effects between the pyridine ring and the cyano group and the trifluoromethyl group affect and restrict each other, so that the entire molecular structure reaches a relatively stable state. However, despite its relatively stable chemical properties, under specific reaction conditions, such as high temperature, strong acid-base or the presence of specific catalysts, some chemical bonds in the compound may still break, which may lead to chemical reactions.
    What are the synthesis methods of (5-chloro-3- (trifluoromethyl) pyridine-2-yl) methanol?
    To prepare (5-alkane-3- (triethyl) pentyl-2-yl) ethane, the synthesis method is as follows:
    First, the nucleophilic substitution reaction of halogenated hydrocarbons can be carried out. First, take an appropriate halogenated alkane and react it with a nucleophilic reagent containing (triethyl) pentyl-2-yl. This nucleophilic reagent can be obtained by certain treatment from the corresponding alcohol or other suitable compounds. The negatively charged part of the nucleophilic reagent attacks the carbon attached to the halogen atom of the halogenated alkane, and the halogen atom leaves, thus forming a carbon-carbon bond, and then builds a carbon skeleton of the target molecule. When reacting, it is necessary to pay attention to the control of the reaction conditions, such as temperature, solvent selection, etc. Suitable solvents may increase the reaction rate and yield, and avoid the occurrence of side reactions.
    Second, the addition reaction of olefins can be used. Find an olefin with a suitable substituent and add it to a specific reagent. For example, if there is a suitable alkene, it can be added to an ethyl-containing reagent under the action of a suitable catalyst. The catalyst can reduce the activation energy of the reaction and promote the smooth occurrence of the reaction. In this process, the reaction conditions must be precisely controlled to ensure that the addition position meets the structural requirements of the target product. The selectivity of the addition reaction is crucial, and it is necessary to adjust the structure of the reactant and the reaction conditions to achieve the desired addition method to generate (5-alkane-3- (triethyl) pentyl-2-yl) ethane.
    Third, the reaction via Grignard reagent can also be considered. Prepare a halogenate containing (triethyl) pentyl-2-yl and make it into Grignard reagent. Then, the Grignard reagent reacts with ethyl-containing carbonyl compounds (such as aldose or ketone). The carbon-magnesium bond in the Grignard reagent has strong polarity, and the carbon is partially negatively charged, which can carry out nucleophilic addition to carbonyl carbon. Subsequent treatment such as hydrolysis can be converted into the target (5-alkane-3- (triethylmethyl) pentyl-2-yl) ethane. During the reaction, the preparation and use of Grignard reagents must be in an anhydrous and anaerobic environment to prevent their failure.
    What are the precautions for (5-chloro-3- (trifluoromethyl) pyridine-2-yl) methanol in storage and transportation?
    In the storage and transportation of (5-alkane-3- (triethylmethyl) to its-2-yl) ethane, many key matters need to be paid attention to.
    First, this substance is quite sensitive to environmental factors. In high temperature environments, it is prone to decomposition reactions, forming products with unstable properties, and may even cause dangerous conditions. Therefore, when storing, it is necessary to choose a cool place, and the temperature should be strictly controlled within a specific range. If the temperature is too high, the intermolecular force will weaken, and the chemical bond will be easily broken, causing its chemical structure to change.
    Second, humidity is also a key factor. The substance is prone to hydrolysis in contact with water, which not only reduces its own purity, but also may release harmful gases. Therefore, the storage place needs to be kept dry to avoid water vapor intrusion. During transportation, it is also necessary to ensure that the packaging is tight to prevent contact with external water vapor.
    Third, about packaging. Materials with good sealing and corrosion resistance should be selected. Due to their active chemical properties, ordinary packaging materials may be corroded, resulting in leakage. Once leaked, it will not only cause material loss, but also pose a threat to the surrounding environment and personnel safety. Packaging materials need to be able to withstand a certain pressure to prevent damage due to factors such as extrusion during transportation.
    Fourth, during transportation, avoid mixing with other chemicals. Because it may react violently with certain substances, causing serious consequences such as combustion and explosion. The transportation route needs to be carefully planned, away from densely populated areas and important facilities to reduce latent risks. At the same time, transportation personnel should receive professional training, familiar with the characteristics of the substance and emergency treatment methods, and can respond quickly and correctly in the event of an accident.