5-Chloro-2-methyl-1h-pyrrolo[2,3-c]pyridine

5-Chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine, this is an organic compound. Its chemical properties are unique, related to its reactivity, stability and many other aspects.
Let's talk about its stability first. In the structure of this compound, the pyridine ring is combined with the pyrrole ring, giving it a certain stability. The conjugation effect of the aromatic system makes the electron cloud more uniform, reducing the energy of the molecule, thereby improving the stability. However, its stability is not absolute. When encountering specific conditions, such as high temperature, strong acid and base, the structure may change.
Re-discussion on the reactivity, chlorine atoms are an important activity check point of this compound. Chlorine atoms have strong electronegativity, which makes the connected carbon atoms partially positively charged and vulnerable to attack by nucleophiles, triggering nucleophilic substitution reactions. In case of nucleophiles such as hydroxyl anions, chlorine atoms may be replaced by hydroxyl groups to form corresponding alcohol derivatives.
2 -methyl groups also affect the properties of compounds. Methyl groups are the power supply groups, which can increase the electron cloud density of the pyrrole ring through induction effects, which affects the reactivity and selectivity of compounds to a certain extent. In the electrophilic substitution reaction, the adjacent and para-sites of methyl groups are more susceptible to electrophilic attack.
In addition, the nitrogen atom of 1H-pyrrolido [2,3-c] pyridine has a lone pair of electrons, which can be used as an electron donor to participate in coordination reactions and form complexes with metal ions, showing unique chemical properties and potential applications. It may have important value in the fields of organic synthesis and medicinal chemistry, and can be used as a key intermediate for the synthesis of complex compounds, or provide a structural basis for the development of new drugs.

The common synthesis methods of 5-chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine, due to the method of organic synthesis, often rely on various reactions. One is through the halogenation and alkylation of pyridine derivatives. First, take a suitable parent pyridine, use a halogenating agent such as a chlorination reagent, and introduce chlorine atoms into the pyridine ring at a specific position under suitable reaction conditions. This halogenation reaction requires detailed investigation of the reaction temperature, time and reagent dosage. If the cap temperature is too high or the time is too long, it is easy to generate polyhalogenated by-products; improper dosage also affects the reaction yield.
Then perform an alkylation reaction to introduce methyl groups. Select an appropriate alkylation reagent, and under the catalysis of a base, connect a methyl group to another position on the pyridine ring. In this step, the type and amount of base have a great impact on the reaction process. If the strong alkalinity is too strong, or other side reactions are induced, the weak base may cause the reaction to be delayed, and the yield is not high.
The second method can be started from pyrrole derivatives. First prepare a pyrrole compound containing a suitable substituent, and then cyclize to construct a pyridine ring to form the target product. During the cyclization reaction, the choice of catalyst is crucial. Different catalysts have different effects on the reaction rate and selectivity. Some catalysts can make the reaction occur in a directional manner to obtain a high-purity target product; but if they are not used as catalysts, or cause cyclization check point confusion, a variety of isomers are generated, which increases the difficulty of separation and purification.
Furthermore, the coupling reaction strategy catalyzed by transition metals can still be used. Select suitable nucleophiles containing halopyridine derivatives and pyrrole structures, and under the action of transition metal catalysts, realize the coupling of carbon-carbon or carbon-heteroatom bonds, and then synthesize the target compound. In this process, the activity and stability of transition metal catalysts, as well as the structure and properties of ligands, all play a significant role in the reaction effect. Catalysts with high activity can accelerate the reaction process, but if the stability is poor, they may be inactivated in the middle of the reaction; the coordination mode between ligands and metals also affects the selectivity and activity of the reaction.

5-Chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine is a special organic compound with important applications in many fields.
It plays a key role in the field of pharmaceutical research and development. Due to its unique chemical structure, it may interact with specific targets in organisms. For example, it can be used as a potential drug intermediate, and after chemical modification, it is expected to develop innovative drugs for specific diseases. It may exhibit a high selective affinity for certain receptors, thereby modulating the signaling pathway in organisms and providing new opportunities for the treatment of difficult diseases such as cancer and neurological diseases.
It also has great potential in the field of materials science. It can be used as a basic unit for building functional materials. Its structure imparts special electrical and optical properties, or it can be used to prepare organic semiconductor materials. Such materials can optimize device performance, improve luminous efficiency, energy conversion efficiency and other key indicators in the fields of organic Light Emitting Diode (OLED), organic solar cells, etc., and promote technological progress in related fields.
In the field of agricultural chemistry, there may be applications. With its impact on certain biological activities, it can be rationally designed and developed, and may become a new type of pesticide ingredient. It can show efficient inhibition or killing effect on specific pests and bacteria, and has higher selectivity and lower environmental toxicity than traditional pesticides, providing assistance for the development of green agriculture.
In summary, 5-chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine has broad application prospects in the fields of medicine, materials, agriculture, etc. With the deepening of research, its potential value is expected to be further explored and utilized.

5-Chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine, this is an organic compound. Its physical properties are particularly important and are related to applications in many fields.
Looking at its properties, under room temperature and pressure, it is mostly in a solid state, but the specific form may vary slightly due to the preparation process and purity, or it is crystalline or powdered, all of which have their own unique appearance.
When it comes to melting point, this compound has a specific melting point value, which is of great significance for identification and purification. After fine determination, the melting point falls in a certain temperature range. This range is the critical temperature range for substances to change from solid to liquid. Accurate grasp of this range is indispensable in research and production.
The boiling point is also one of the key physical properties. Under specific pressure conditions, the compound boils and converts to a gaseous state, and its boiling point value reflects the strength of intermolecular forces. Knowing the boiling point can effectively control the temperature during separation and purification and achieve precise operation.
In terms of solubility, 5-chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine exhibits different solubility properties in different solvents. In organic solvents, such as common ethanol, dichloromethane, etc., it may have a certain solubility, but the solubility in water is relatively limited. This property is a factor that needs to be carefully considered in the synthesis of compounds, the selection of reaction media, and subsequent separation steps.
Density is also a key consideration. The determination of the density of the compound can help to understand the relationship between its mass and volume, and provide necessary data support in practical applications, such as material ratio, reaction system design, etc.
In addition, its appearance color is also one end of the physical properties. The pure 5-chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine may be colorless to light yellow, and the color change may reflect its purity, which can also provide intuitive reference information for research and production processes.
In summary, the physical properties of 5-chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine, from properties, melting point, boiling point, solubility, density to color, are interrelated, which together constitute the physical property map of the compound, laying a solid foundation for its in-depth research and wide application in many fields such as chemistry and medicine.

What you are asking about is the market price of "5-chloro-2-methyl-1H-pyrrolido [2,3-c] pyridine". This is a fine chemical, and its market price often changes due to various reasons, and it cannot be generalized.
First, the simplicity of the production process has a great impact on the price. If the preparation of this compound requires multiple reactions, and the reaction conditions of each step are harsh, special reagents or catalysts are required, the cost will be high, and the price will rise accordingly. On the contrary, if the process is simple and efficient, the price may be relatively close to the people.
Second, the purity is also the key. High-purity products require finer purification processes, consume more resources and energy, and the price is often higher than that of low-purity products. If you want to use it for high-end scientific research or pharmaceutical synthesis, you must have high purity, and its price is naturally high.
Third, the market supply and demand situation determines the price. If the demand for this compound increases sharply during a certain period of time, but the supply is limited, such as a sudden increase in demand for a new drug research and development, and it is difficult for the manufacturer to increase production significantly for a while, the price will rise. On the contrary, if the supply exceeds the demand, the price will easily decline.
Fourth, the region and scale of the manufacturer also have an impact. Production costs vary in different regions. Due to the scale effect, the unit cost of large manufacturers may be lower than that of small factories, and the price may vary.
However, we do not have the exact market price. If you want to know more, you can consult chemical product suppliers, chemical raw material trading platforms, or relevant industry exhibitions for the latest and accurate price information.