5-Chloro-2-hydroxy-4-iodopyridine

5-Chloro-2-hydroxy-4-iodopyridine is an organic compound with unique chemical properties. Its appearance is often white to light yellow crystalline powder, which can exist stably under specific conditions.
From a structural perspective, the substitution of chlorine, hydroxyl and iodine atoms on the pyridine ring gives the compound special reactivity. Hydroxyl groups are nucleophilic because their oxygen atoms contain lone pairs of electrons, which can participate in many nucleophilic substitution reactions. For example, in the presence of suitable bases, the hydrogen of hydroxyl groups can be replaced by other groups to form new derivatives. This property can be used in organic synthesis to construct complex molecular structures. The presence of
chlorine atoms also affects the properties of compounds. Although chlorine has stronger electron-absorbing ability than iodine, its electronegativity reduces the electron cloud density of the pyridine ring and changes the electrophilic substitution activity on the ring. For example, in the aromatic electrophilic substitution reaction, the positioning effect of chlorine atoms will affect the position of new substituents entering the pyridine ring.
Iodine atoms are relatively large, and their introduction increases the molecular volume and mass of compounds, affects the intermolecular forces, and has effects on physical properties such as melting point and boiling point. And iodine atoms can be used as leaving groups under specific reaction conditions, participating in coupling reactions, etc., providing the possibility for the construction of carbon-carbon bonds or carbon-heteroatom bonds.
The chemical properties of 5-chloro-2-hydroxy-4-iodopyridine make it potentially valuable in the fields of medicinal chemistry and materials science. In drug development, its unique structure may interact with specific biological targets to exhibit pharmacological activity; in material synthesis, its reactivity can prepare functional materials with special properties.

5-Chloro-2-hydroxy-4-iodine pyridine is also an organic compound. The common synthesis methods are about the following ends.
One is halogenation. First take the appropriate pyridine derivative, and under specific reaction conditions, use a halogenated reagent to perform halogenation reaction. If you choose a pyridine containing hydroxyl groups, introduce chlorine atoms with chlorine reagents, and then undergo iodine substitution reaction to make the iodine atoms connect at the designated position. This process requires attention to the precise control of reaction conditions, such as temperature, reaction time, reagent dosage, etc. Due to different conditions, or the yield and purity of the product vary.
The second is the functional group conversion method. Pyridine derivatives with similar structures are used as starting materials, and the target product is obtained by the gradual transformation of functional groups. First, the functional groups of the starting materials are modified to make them have activity check points that can be further reacted. After a series of reactions, such as substitution, oxidation, reduction, etc., the structure of the target molecule is successively constructed, and the final 5-chloro-2-hydroxy-4-iodopyridine is obtained. This approach requires familiarity with the mechanism of each step of the reaction to ensure that the reaction proceeds in the desired direction.
The third is the metal catalytic synthesis method. Using the unique activity and selectivity of metal catalysts, the reaction of the catalytic substrate occurs. For example, transition metal catalysts, in the coordination of suitable ligands, promote the coupling reaction of pyridine derivatives and halogenated reagents to achieve the precise introduction of chlorine atoms and iodine atoms. This method can often improve the reaction efficiency and selectivity, but the choice of metal catalysts and the optimization of the reaction system are very critical, which is related to the success or failure of the reaction and the quality of the product.
All this synthesis method has its own advantages and disadvantages. In practical applications, the ideal synthesis effect can be achieved only when considering the availability of raw materials, the difficulty of the reaction, and the consideration of cost.

5-Chloro-2-hydroxy-4-iodopyridine, this compound is useful in many fields such as medicine, pesticides and materials.
In the field of medicine, it can be used as a key intermediate to help synthesize compounds with unique biological activities. For example, when developing new antibacterial drugs, this is used as a starting material through a series of chemical transformations, or a molecular structure can be constructed that exhibits high-efficiency inhibitory activity against specific pathogens. Because of the presence of chlorine, hydroxyl and iodine atoms in its structure, it endows the molecule with unique electronic effects and spatial resistance, which can precisely combine with key targets in bacteria and interfere with the normal physiological activities of bacteria, thus achieving the purpose of antibacterial.
In the field of pesticides, 5-chloro-2-hydroxy-4-iodopyridine is also of great value. It can be chemically modified to create new insecticides or fungicides. For example, the modified compound may specifically act on specific enzymes or receptors in pests or pathogens by virtue of its special structure, blocking their normal growth, development and reproduction paths, and because it is relatively friendly to the environment, it has great potential in the development of green pesticides.
In the field of materials science, this compound may be used to prepare functional materials. For example, in the field of organic optoelectronic materials, with its unique electronic properties, it may be able to participate in the construction of high-efficiency organic Light Emitting Diode (OLED) materials to optimize the luminous efficiency and stability of materials. The heteroatoms and hydroxyl groups in its structure can adjust the electron transport and energy level structure of the material, so that OLED has better performance in display and lighting.
In short, 5-chloro-2-hydroxy-4-iodopyridine has broad application prospects in the pharmaceutical, pesticide and materials industries due to its unique structure. With the continuous deepening of research, it is expected to bring new opportunities for the development of various fields.

I don't know the market price range of 5-chloro-2-hydroxy-4-iodopyridine. This compound is not commonly available, and its price often varies due to various factors.
First, the difficulty of preparation is very important. If the preparation requires complicated steps, expensive raw materials or special conditions, its price must be high. To synthesize this pyridine derivative, the introduction of chlorine, iodine and hydroxyl groups may require fine reaction control, and the yield and purity of each step of the reaction affect the final cost.
Second, market demand also affects the price. If it has specific and large demand in the fields of pharmaceutical research and development, materials science, etc., the price may fluctuate due to supply and demand. If it is only needed for niche scientific research, the output is limited, and the price may be expensive.
Third, the price varies depending on the supplier. Large suppliers may have slightly lower costs due to scale effects; small suppliers may have different pricing due to operating costs and other reasons. And different regions have different prices due to differences in transportation, taxes, etc.
Fourth, quality and purity have a great impact on the price. High purity products are often used in high-end scientific research and pharmaceutical production, and the price is higher than that of ordinary purity products.
To know the exact price range, you should consult chemical raw material suppliers, chemical reagent sales platforms, or refer to relevant industry reports and market surveys. However, it is difficult for me to determine the price range at the moment.

5-Chloro-2-hydroxy-4-iodopyridine is also a chemical substance. If you want to store it properly, you must explain its storage.
This material may be unstable and afraid of light and heat. Therefore, it should be stored in a cool, dry and well-ventilated place. Avoid direct light to prevent it from changing due to photochemical reactions. High temperature can also cause its quality to change, so the storage temperature should be low, not exceeding the usual room temperature.
In addition, it must be stored alone or in combination with other things, and should not coexist with strong oxidation or reduction substances. To prevent violent response and danger. The packaging should also be strict, and an airtight device should be used to prevent air and moisture from entering. Due to moisture or hydrolysis, its quality will be damaged.
When storing, it should also be checked frequently to see if its shape has changed, such as color, taste, and state. If there is any change, quickly investigate the cause and take measures to deal with it. The memory of storage should not be ignored, and the time, quantity and storage status of it should be recorded for tracking. In this way, the quality of 5-chloro-2-hydroxy-4-iodopyridine should be kept stable, and the expected effect should be achieved when used.