As a leading 5-Chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylicacid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 5-Chloro-1H-pyrrolo [2,3-c] pyridine-2-carboxylic acid
5-Chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid, this is an organic compound. Its chemical properties are quite rich.
First of all, its acidity is acidic because it contains a carboxyl group (-COOH). The hydrogen atoms in the carboxyl group can be partially ionized, releasing protons (H 🥰) in aqueous solution, thus exhibiting acidic properties. This acidity allows it to neutralize with bases, such as with sodium hydroxide (NaOH). The hydrogen of the carboxyl group combines with hydroxide (OH) to form water, resulting in the corresponding carboxylate and water.
Then its substitution reactivity. The compound contains chlorine atoms, which can participate in the substitution reaction. Because the electron cloud density of the carbon atoms connected to the chlorine atoms is affected by the pyrrolido-pyridine ring, the chlorine atoms have certain activity. For example, when a suitable nucleophilic reagent exists, the nucleophilic reagent can attack the carbon atoms connected to the chlorine, and the chlorine atoms leave, resulting in a nucleophilic substitution reaction.
In addition, the pyrrolido-pyridine ring endows the compound with a unique electron conjugation system. This conjugation system affects the electron distribution and stability of the molecule, which in turn affects its chemical activity. The conjugation system delocalizes the electrons in the molecule, enhances the stability of the molecule, and also changes the electron cloud density of each atom on the ring, which affects the reactivity
The compound may also participate in cyclization reactions, etc. The active check point on the pyrrolido-pyridine ring interacts with other groups in the molecule. Under suitable conditions, intramolecular cyclization reactions can occur to construct more complex cyclic structures, further enriching its chemical properties and reaction pathways.
What are the main uses of 5-Chloro-1H-pyrrolo [2,3-c] pyridine-2-carboxylic acid
5-Chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid, an organic compound, has a wide range of uses and can be found in many fields.
In the field of medicinal chemistry, it is often a key intermediate for the creation of various potentially biologically active drug molecules. The structural properties of this compound may allow it to interact with specific targets in organisms, thereby exhibiting pharmacological activities such as antibacterial, anti-inflammatory, and anti-tumor. For example, by modifying and optimizing its structure, researchers may be able to design and synthesize new small molecule drugs to treat specific diseases and contribute to human health and well-being.
In the field of materials science, 5-chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acids also have unique uses. Due to their specific electronic properties and structural rigidity, they can be used as building blocks to participate in the synthesis of functional materials. For example, in organic optoelectronic materials, such compounds or adjustable optical and electrical properties of materials can be used in organic Light Emitting Diodes (OLEDs), solar cells and other devices to improve their performance.
In addition, in the field of organic synthesis chemistry, this compound is also an important synthetic building block. With its unique functional groups and reactivity, chemists can connect it with other compounds through various organic reactions, build complex and diverse organic molecules, expand the boundaries of organic synthesis, and provide more possible paths for the creation of new compounds. In short, 5-chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acids play an important role in many scientific fields with their unique structures and properties, promoting research and development in various fields.
What are the synthesis methods of 5-Chloro-1H-pyrrolo [2,3-c] pyridine-2-carboxylic acid
The synthesis method of 5-chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid is an important topic in the field of organic synthesis. This compound has potential application value in many fields such as medicinal chemistry. There are many synthetic methods, each with its own advantages and disadvantages.
In the past, there were those who used specific pyridine derivatives as starting materials. First, the pyridine derivative underwent a halogenation reaction under specific reaction conditions to introduce chlorine atoms. This step requires precise control of the reaction temperature, the proportion of reactants and the reaction time. After the halogenation reaction is completed, a suitable reagent is used to guide the inner cyclization of the molecule to construct the core structure of pyrrolido-pyridine. In this process, the choice of reaction solvent, the type and amount of catalyst have a significant impact on the yield and selectivity of the reaction.
There are also pyrrole derivatives as starters. By ingeniously designing the reaction path, the specific position of the pyrrole derivative is modified first, and then the condensation reaction is carried out with the pyridine-related fragment. In this path, the optimization of the condensation reaction conditions is extremely critical, such as the regulation of the pH of the reaction system, the reaction time and temperature, all of which are related to the purity and yield of the final product.
Another synthesis strategy uses transition metal catalysis. Transition metal catalysts can effectively promote the reaction and improve the reaction efficiency and selectivity. However, the requirements of this method are quite high, and the cost of the catalyst may be a factor limiting its large-scale application. Appropriate transition metal catalysts and their ligands need to be carefully screened, and the reaction conditions need to be optimized to achieve the ideal synthesis effect.
All these synthetic methods need to be carefully selected and optimized by synthesizers according to their actual needs, experimental conditions, and expectations of product purity and yield, in order to achieve the purpose of efficient synthesis of 5-chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid.
What is the price range of 5-Chloro-1H-pyrrolo [2,3-c] pyridine-2-carboxylic acid in the market?
I don't know the price range of 5-chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid on the market. This compound may have applications in the chemical and pharmaceutical fields, but its price is affected by many factors.
First, the production scale is related to the price. If it is produced in large quantities, the unit cost may decrease due to the scale benefit, and the price will also decrease; if it is produced in small quantities, the cost will be high, and the price will be high.
Second, the purity has a great impact. For high purity, the preparation process is complicated, and more processes and costs are required to remove impurities, so the price must be higher than for low purity.
Third, market supply and demand are the key. < Br >
Fourth, the cost of raw materials affects the price. If the raw materials for preparing this acid are rare or expensive, the price of the product will also rise.
And different suppliers have different pricing strategies, which also makes the price different. To know the exact price range, you can get a more accurate price range by consulting chemical raw material suppliers, chemical trading platforms or researching at relevant industry exhibitions.
What are the storage conditions for 5-Chloro-1H-pyrrolo [2,3-c] pyridine-2-carboxylic acid?
5-Chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid, this is a fine chemical, and its storage conditions are very critical.
Because of its certain chemical activity, it needs to be stored in a dry place. Moisture can easily cause it to chemically react, or deliquescent and deteriorate, which changes its chemical properties and affects subsequent use. It should be placed in a dryer or a storage container with a desiccant, and it is better to maintain the environmental dryness below 40% relative humidity.
Temperature also has a significant impact. Avoid high temperature, high temperature or cause it to decompose, accelerate chemical reactions, and reduce quality. In general, the storage temperature should be controlled in a refrigerated environment of 2-8 ° C. If the conditions are not acceptable, it should also be placed in a cool place so that the temperature does not exceed 30 ° C.
Light should not be ignored. This compound is sensitive to light, and light or photochemical reactions can cause structural changes. It must be stored in an opaque container, such as a brown glass bottle, or in a light-proof cabinet to prevent direct light.
In addition, in order to prevent impurities from mixing and causing contamination, the storage container must be clean and well sealed. After use, it should be sealed quickly to reduce the contact time with air. In this way, Fangbao 5-chloro-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid is stable during storage and has the same quality as before.