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What is the chemical structure of 5-chloro-1h-pyrrolo [2,3-b] pyridine-2-carboxyli
5-Chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid, this is an organic compound. Looking at its name, its structure can be analyzed. "5-Chloro" shows that the chlorine atom is attached to the 5th position of the pyrrolido [2,3-b] pyridine parent nucleus. Pyrrolido [2,3-b] pyridine, which is formed by fusing the pyrrole ring with the pyridine ring, has a unique ring structure. "1H" indicates that the hydrogen atom is attached to the 1st position of the pyrrole ring. And "-2-carboxylic acid" indicates that there is a carboxyl group attached to the 2nd position of the fused ring structure.
In the ancient language, it is said: "The name of this compound is 5-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid. In its structure, the chlorine atom occupies the fifth position of the pyrrolido [2,3-b] pyridine parent nucleus. Pyrrolido [2,3-b] pyridine is a ring system formed by fusing the pyrrole ring with the pyridine ring. 1H indicates that the hydrogen atom is in one of the pyrrole rings. As for the -2-carboxylic acid, it indicates that the two positions are connected with carboxyl groups." The structure of this compound, in the field of organic chemistry, can be used in many aspects such as organic synthesis and drug development due to its unique ring system and substituent distribution, or specific chemical properties and reactivity.
What are the main uses of 5-chloro-1h-pyrrolo [2,3-b] pyridine-2-carboxyli
5-Chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate, and the synthesis of many drugs depends on its construction of specific chemical structures. Due to its unique nitrogen heterocycle, it endows drugs with diverse biological activities, or can participate in the creation of antibacterial drugs to inhibit the growth of pathogens; or in the development of anti-cancer drugs, its structural characteristics interfere with the physiological process of cancer cells, contributing to the solution of cancer problems.
In the field of materials science, it also has potential value. By virtue of its own chemical properties, it may participate in the preparation of new organic materials, such as optoelectronic materials. After being treated by a specific process, or to make the material have unique photoelectric properties, it is used in the fields of Light Emitting Diode, solar cells, etc., providing the possibility for the progress of energy and display technology.
In the field of pesticide chemistry, it may form the basis for the creation of new pesticides. Using its impact on biological activity, we can develop pesticides with high efficiency and low toxicity, precisely attack pests, protect the healthy growth of crops, and reduce the harm to the environment, which is in line with the current needs of green agriculture development.
In addition, in the field of organic synthetic chemistry, it is an important building block for organic chemists to build complex organic molecular structures. Through ingenious chemical reactions, many novel compounds are derived, expanding the library of organic chemicals, and laying the foundation for subsequent scientific research and application development.
What are the synthesis methods of 5-chloro-1h-pyrrolo [2,3-b] pyridine-2-carboxyli
The synthesis of 5-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acids is an important topic in the field of chemistry. There are many paths to follow for its synthesis.
One of them can be started from a specific pyridine derivative. Through halogenation reaction, chlorine atoms are introduced into a suitable position. This step requires the selection of suitable halogenating reagents and reaction conditions, such as in a specific solvent, with a specific halogenating agent, and reacting at a specific temperature, chlorine atoms can be precisely introduced to obtain chloropyridine-containing intermediates. Subsequently, the pyrrole ring is constructed by cyclization reaction. This process may require a specific catalyst and reaction environment. By clever regulation, the molecule is cyclized and rearranged to form the target pyrrole-pyridine structure. Finally, for a specific position on the pyridine ring, through carboxylation reaction, carboxyl groups are introduced to achieve 5-chloro-1H-pyrrole [2,3-b] pyridine-2-carboxylic acid. This carboxylation step also requires careful selection of reagents and conditions to ensure that the reaction proceeds smoothly and has good selectivity.
Second, there are also pyrrole derivatives as starting materials. First, the pyrrole ring is modified to introduce pyridine-related structural units. This process requires the help of a series of organic reactions, such as nucleophilic substitution, condensation, etc. Then, through halogenation, chlorine atoms are introduced at appropriate check points, and then the pyridine part is carboxylated. In each step, the selectivity, yield and avoidance of side reactions need to be considered. Each step of the reaction needs to be carefully controlled. Many factors, from the purity and dosage of reagents to the reaction temperature and time, are related to the quality and yield of the final product. In this way, the effective synthesis of 5-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid can be achieved through the exploration and optimization of different paths.
What are the physical properties of 5-chloro-1h-pyrrolo [2,3-b] pyridine-2-carboxyli
5-Chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid, which is an organic compound. Its physical properties are many and closely related to its structure.
Looking at its morphology, it is mostly crystalline solid under normal conditions. Due to the strong interaction between molecules, it is arranged in an orderly manner and forms a regular lattice structure. Its color is often white or off-white, and its pure state is completely white. However, when it contains impurities, the color may change slightly.
When it comes to the melting point, it is about a specific temperature range. Due to the fixed chemical bond force between atoms in the molecular structure, the corresponding energy needs to be reached when heated to break the lattice and cause the solid state to turn into a liquid state. Accurate melting point is of great significance for the identification of compounds and is an important indicator of the purity and characteristics of substances.
In terms of solubility, it varies from common organic solvents. In polar organic solvents, such as methanol and ethanol, there is a certain solubility, and its molecules have polar groups, which can form hydrogen bonds or other interactions with polar solvent molecules to increase their solubility. In non-polar organic solvents, such as n-hexane, the solubility is very small, because the molecular polarity does not match the non-polar solvent.
In addition, the density of the compound is also one of the inherent physical properties, which reflects its unit volume mass and is related to the molecular structure and packing method. Its density may vary slightly under different temperature and pressure conditions, and this property needs to be carefully considered in chemical production and experimental operations.
Its physical properties are of great significance to the synthesis, separation, purification and application of the compound. Knowing these properties allows chemists to reasonably select solvents and control reaction conditions in experiments and production to achieve the best reaction effect and product quality.
What is the market outlook for 5-chloro-1h-pyrrolo [2,3-b] pyridine-2-carboxyli
5-Chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid, an organic compound with great potential, has shown unique value in the fields of medicine, pesticides and so on. In terms of its market prospects, it is like the morning sun, and it is gradually booming.
Looking at the field of medicine, with the progress of scientific research, the research on specific disease therapeutic targets continues to deepen. 5-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid, due to its unique chemical structure, may be used as a key intermediate to synthesize innovative drugs with high efficiency and low toxicity. At present, many pharmaceutical companies and scientific research institutions are making efforts in this direction, dedicated to exploring its application in the research and development of anti-cancer, antiviral and other drugs. With time, if a breakthrough can be achieved, it will be able to gain a place in the pharmaceutical market, and the prospects are limitless.
The field of pesticides should not be underestimated. With people's increasing attention to the quality of agricultural products and environmental safety, it is urgent to develop efficient and environmentally friendly pesticides. The characteristics of this compound may make it stand out in the creation of new pesticides, helping to develop green and sustainable pesticide products. Once successful, it is expected to occupy an important share in the pesticide market in line with market demand.
However, its market expansion is not smooth. The optimization of the synthesis process is a major challenge. It is necessary to increase the yield and reduce the cost in order to enhance the competitiveness. Furthermore, regulations and regulations are becoming more and more stringent, and products must meet many safety and environmental standards. But overall, although 5-chloro-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid is in the early stage of development, it is like a jade to be polished. After grinding, it will be able to bloom and win a wide world in the market.