5 Bromopyridine 2 4 Diamine
pyridine pyrrole pyrazine piperidine piperazine

5-Bromopyridine-2,4-diamine

    Specifications

    HS Code

    638087

    Chemical Formula C5H6BrN3
    Molecular Weight 188.026
    Appearance Solid (predicted)
    Boiling Point 347.4°C at 760 mmHg (predicted)
    Melting Point 170 - 174°C
    Density 1.746 g/cm³ (predicted)
    Flash Point 163.9°C (predicted)
    Solubility Soluble in organic solvents like DMSO, DMF (predicted)
    Pka pKa1:10.68 (predicted for the amino group)
    Refractive Index 1.695 (predicted)

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    General Information
    Where to Buy 5-Bromopyridine-2,4-diamine in China?
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    Frequently Asked Questions

    As a leading 5-Bromopyridine-2,4-diamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-bromopyridine-2,4-diamine?
    5-% hydroxyampicillin-2,4-diketone, which is also listed in the ancient texts of Dan, has a wide range of main uses, which are described in detail by you.
    First, in the way of medicine, this substance is often used by doctors to treat various diseases. Its mild nature has the effect of removing blood stasis and generating new ones, and helping the right and eliminating evil spirits. In many medical records in the past, there were drugs containing 5-% hydroxyampicillin-2,4-diketone to cure diseases of disharmony of the viscera and poor qi and blood. For example, for the disease of full stomach and not thinking about diet, doctors use exquisite compatibility to integrate this medicine, which can make the spleen, stomach and qi smooth and the diet gradually recover. Or it can be used to treat trauma carbuncle, reduce swelling and pain, promote its carrion shedding, and grow new muscles. It is a good material for doctors to help the world and save people.
    Second, in the art of alchemy and pharmaceuticals, 5-% hydroxyamphenyl-2,4-dione is also indispensable. In ancient alchemy stoves, this substance participates in the refining process of many medicinal pills. It can reconcile the properties of various medicinal pills, making the efficacy of medicinal pills more significant and stable. In ancient times, alchemists pursued the elixir of immortality. In the elixir formulas that have been tempered for thousands of times, 5-% hydroxyampicillin-2,4-dione is often used as the key, either to help the elixir condense the essence or to make the effect of the elixir more lasting. Although the wish of longevity has not been fulfilled, its importance in alchemy is evident.
    Third, among the folk remedies, there are also many figures of 5-% hydroxyampicillin-2,4-dione. In the long-term struggle with diseases and the exploration of herbal medicine, folk wise men found that this substance can be used for the simple treatment of some common diseases. In case of itchy skin, wash it with herbs containing this ingredient to relieve the pain of itching; or for some mild joint pain, incorporate 5-% hydroxyampicillin-2,4-dione into it with a specific formula and apply it to the affected area, which can relieve pain, relieve joint discomfort, and provide convenience for the daily treatment of common people.
    What are the synthesis methods of 5-bromopyridine-2,4-diamine?
    There are many synthetic methods of 5-bromopyridine-2,4-dicarboxylic acid, which are described in detail today.
    First, pyridine is used as the initial raw material. First, bromine atoms are introduced into the pyridine ring by halogenation reaction, and bromine atoms are selected from liquid bromine and N-bromosuccinimide (NBS). Under suitable reaction conditions, such as specific temperature and catalyst, the bromine atoms are precisely positioned at the 5-position of the pyridine ring. Subsequently, after a series of oxidation steps, specific groups on the pyridine ring are converted into carboxyl groups to achieve the synthesis of 5-bromopyridine-2,4-dicarboxylic acid. In this path, the key to the oxidation process is to select a suitable oxidant, such as potassium permanganate, potassium dichromate, etc., and to precisely control the reaction conditions to avoid excessive oxidation.
    Second, start from the pyridine derivatives containing specific substituents. If there are already some groups that can be converted into carboxyl groups on the starting material pyridine ring, or check points that are easy to introduce bromine atoms, the reaction sequence can be cleverly designed to achieve the introduction of bromine atoms first, and then the existing substituents can be converted into carboxyl groups through appropriate reactions. For example, if there are groups such as methyl groups that can be oxidized to carboxyl groups on the raw material pyridine ring, the bromination reaction is carried out first, and then treated with a suitable oxidant to obtain the target product. This approach requires a precise understanding of the structure of the starting material, and a reasonable reaction process is planned according to its characteristics.
    Third, the coupling reaction with the help of metal catalysis. Pyridine halide containing bromine atoms and organometallic reagents containing carboxyl groups or convertible to carboxyl groups can be selected. Under the action of metal catalysts, carbon-carbon bonds can be coupled to construct the molecular structure of 5-bromopyridine-2,4-dicarboxylic acid. Commonly used metal catalysts such as palladium and nickel require fine regulation of the pH of the reaction system, reaction temperature, and catalyst dosage to ensure the high efficiency and selectivity of the reaction.
    All the above synthesis methods have their own advantages and disadvantages. In actual operation, the most appropriate method should be carefully selected according to various factors such as the availability of raw materials, the controllability of reaction conditions, and the purity requirements of the target product.
    What are the physical and chemical properties of 5-bromopyridine-2,4-diamine?
    The physicochemical properties of 5-hydroxytryptamine-2,4-diamino are as follows:
    5-hydroxytryptamine-2,4-diamino, this material is light yellow, crystalline at room temperature, and fine in texture. Its melting point is quite high, about [X] ° C, and it melts in a hot topic environment. This characteristic is due to the strong force between molecules. The boiling point is also correspondingly high, reaching [X] ° C at a specific pressure. To boil it into a gaseous state, a large amount of thermal energy needs to be applied.
    When it comes to solubility, its solubility in water is limited, only slightly soluble. However, when encountering alcohol solvents, such as ethanol, methanol, etc., the solubility is increased and it is soluble. This is because the molecules of the substance can form special interactions with alcohol molecules, such as hydrogen bonds, which increases the degree of solubility.
    Its chemical stability is also considerable, and it can be stored for a long time under normal environmental conditions without easy deterioration. However, when encountering strong oxidizing agents, it is easy to react and the molecular structure is damaged. This is because strong oxidizing agents have extremely strong electron-grabbing ability, and some groups in 5-hydroxytryptamine-2,4-diamino molecules are prone to electron loss and are oxidized. In case of strong acid and alkali, it will also react, or protonate, or deprotonate, resulting in changes in molecular structure and properties.
    Its density is higher than that of water, and it will sink to the bottom when placed in water. And it has a certain degree of hygroscopicity. In a humid environment, it is easy to absorb water vapor in the air, resulting in changes in its own properties, so it needs to be stored in a dry place.
    What is the price range of 5-bromopyridine-2,4-diamine on the market?
    In today's market, the price of 5-base-2,4-dipyridine is high, so to speak. The price of the product varies due to various reasons, such as supply and demand, manufacturing methods, materials, and market conditions.
    If there is supply and demand, the demand will be high, and the supply will not be high, and the supply will be high. Supply and demand will be high or low. The method of manufacturing is also low. If there is any new product, the quantity will increase, the cost will be high, and the cost will be low. The cost of materials is also high. The cost of materials is also high, and the cost of finished products will also be high. And the market is high, the business is high, and the government's decree is high, all of which can make the Gebo.
    In general, in the past, the value of the value may vary from [X1] to [X2]. This word is a rough estimate and is not determinable. To know the value, it is advisable to contact the dealer, the manufacturer, or the recent transaction to get the nearest value.
    What are the storage conditions for 5-bromopyridine-2,4-diamine?
    The storage material of 5-yl-2,4-dinitro should be investigated. This material should be stored in a room that is clean and clear. Due to its special properties, it needs to be exposed to fire and gas sources, and it is not easy to produce dangerous substances.
    And the temperature should not exceed 30 ° C, and the phase degree should not exceed 80%, so as to maintain its chemical properties. It should be stored in parts such as raw materials, active gold powders, acids, and edible chemicals, and should not be mixed to prevent accidents due to interaction.
    There are suitable materials to contain leaks. When moving this material, the operator must wear anti-pollution equipment and be careful to prevent the package and container from being damaged. If this material does not leak, it will quickly isolate the leakage and pollution, restrict access, and cut off the fire source. Emergency managers need to wear a protective mask (full mask), wear a gas suit, and do not directly contact leaks. Small leaks can be collected with inert materials such as dry sand and vermiculite; large leaks need to be collected by dike or dig a pit, covered with foam to reduce the damage of steaming, and then moved to the tank with a pump or a collector for recycling or storage. In this way, the safety of 5-base-2,4-dinitro can be guaranteed during storage and use.