5-bromo-6-chloropyridine-3-carboxylic acid

The chemical properties of 5 + -mercury-6 + -bromine to its -3 + -carboxylic acid are toxic to mercury. Mercury is a silver-white liquid metal that can evaporate at room temperature. Mercury vapor is highly toxic and can cause serious damage to the nervous system and kidneys after inhalation. Bromine is highly oxidizing, corrosive and irritating. Bromine is a reddish-brown smoky liquid. Its vapor is strongly irritating, can irritate the eyes and respiratory mucosa, and is highly corrosive to the skin. Carboxylic acids are acidic and can neutralize with bases to form salts and water. For example, acetic acid reacts with sodium hydroxide to form sodium acetate and water; it can also be esterified with alcohols. Under the catalysis and heating conditions of concentrated sulfuric acid, esters and water are formed. Like acetic acid and ethanol react to form ethyl acetate and water. In addition, some carboxylic acids can also undergo decarboxylation reactions. These three substances, mercury and bromine, are highly dangerous, and need to be used with extreme caution and follow strict safety procedures when using and storing. Carboxylic acids are widely used in organic synthesis and other fields, and need to be used reasonably according to their specific properties.

There are three ways to make "5-hydrocarbon-6-hydrocarbon-3-carboxylic acid", and let me tell you one by one.
First, a compound containing a specific functional group is used as the starting material. Select a hydrocarbon derivative with active chemical bonds, which can be introduced into halogen atoms through halogenation under mild reaction conditions. This halogen atom is extremely critical and is the activity check point of subsequent reactions. Then, the halogen-containing compound undergoes a nucleophilic substitution reaction with sodium cyanide, and the cyanyl group is successfully introduced. The cyanyl group can be skillfully converted into a carboxyl group by hydrolysis, resulting in "5-6-cyanobarbital-3-carboxylic acid". This process requires controlling the reaction temperature and pH. If the temperature is too high or too low, and the pH is not suitable, the reaction yield can be low, and even the reaction fails.
Second, with the help of the wonderful method of Grignard's reagent. First, take a suitable halogenated hydrocarbon, react with magnesium in anhydrous ether, and carefully prepare Grignard's reagent. This Grignard reagent is very active and can react quickly when exposed to carbon dioxide to form carboxylate. Then, after acidification treatment, the carboxylate is converted into the target "5-6-hexagonal-3-carboxylic acid". However, when preparing Grignard's reagent, the reaction environment is strict, and it needs to be absolutely anhydrous and oxygen-free, otherwise Grignard's reagent is highly susceptible to inactivation, resulting in the inability of the reaction to proceed.
Third, start with aldosterone compounds. Using the carbonyl properties of aldosterone, a specific group is first introduced through an addition reaction. For example, it is added with an organometallic reagent with a suitable substituent to form an alcohol intermediate. This intermediate can be oxidized to convert the alcohol hydroxyl group into a carboxyl group. This oxidation step requires the selection of an appropriate oxidizing agent. If the oxidizing agent is too strong, it may be over-oxidized and destroy the molecular structure; if the oxidizing property is insufficient, the conversion of carboxyl groups cannot be achieved.
These three production methods have their own advantages and disadvantages. The first method is common and easy to obtain raw materials, but there are a little more reaction steps; the second method is simple in steps, but it requires harsh reaction conditions; the third method can take advantage of the diverse properties of aldosterone and ketone to introduce different substituents flexibly, but the control of the oxidation step is quite difficult. It is necessary to weigh the advantages and disadvantages according to the actual situation and choose the best synthetic route.

Mercury of 5 + -, mercury of 6 + -, and citric acid of 3 + - are widely used and are involved in various fields.
Mercury, in the field of medicine, used to make medicinal pills in the past, hoping for longevity, but now its toxicity is known, so it is rarely used. However, in the chemical industry, mercury can be used as a catalyst to help the reaction proceed. And mercury lamps also rely on mercury to generate light, and the lighting effect is quite good. In the metallurgical industry, mercury can be used to extract gold, so that it can form amalgam with gold, which is easy to separate. < Br >
Mercury cyanide is highly toxic. However, in electroplating, mercury cyanide is often used as a raw material to coat the metal surface with a uniform layer to increase its appearance and corrosion resistance. In some special chemical reactions, mercury cyanide can be used as a reagent to promote the reaction to follow a specific path.
Citric acid, in the food industry, is often used as a sour agent to increase the flavor of food, and has anti-corrosion effects, which can extend the shelf life of food. In the genus of medicine, citric acid can be used as a buffer to adjust the pH of preparations and ensure the stability of drugs. In the chemical industry, citric acid can be used as a chelating agent to combine with metal ions to remove the interference of metal ions on the reaction. It is also used in the production of detergents to help decontaminate them.
Although these three have different uses, they should be used with caution to prevent harm to the environment and human health.

The price of the Guanfu market is related to changes in supply and demand, and also depends on the quality of materials. As for the 5% mercury, 6% antimony lead, and 3% boric acid you mentioned, it is not easy to know the price, because the price often changes with the market.
Mercury is a toxic metal element, which is widely used in the chemical industry, instrumentation and other industries. Its price is often affected by many factors such as mineral abundance, difficulty in mining, and environmental regulations. If minerals are abundant, mining is convenient, and environmental regulations are slightly wider, the price may stabilize and decrease slightly; if minerals are scarce, mining is difficult, and environmental regulations are strict, the price will rise.
Antimony and lead, or lead-antimony alloys, which are widely used in batteries, solder and other industries. The change in price is related to the price of lead and antimony, as well as the process and cost of alloy preparation. If the price of lead and antimony rises, the preparation cost increases, the price of antimony and lead also increases; otherwise, it decreases.
Boric acid has a wide range of uses and is indispensable in glass, ceramics, medicine and other industries. Its price is determined by the supply of boric acid raw materials, the progress of production technology, and the prosperity and decline of market demand. If the supply of raw materials is sufficient, the technology is advanced, and the demand is stable, the price will be stable; if the raw material is in short supply, the technology is stagnant, and the demand is greatly increased, the price will be high.
If you want to know the exact market prices of these three things at present, you should carefully observe the dynamics of the cities, visit the merchants of the various banks, and refer to the reports of the industry, so that you can get their approximate prices. However, the market conditions are ever-changing, and the price is also volatile. You must always pay attention to it so as not to misjudge.

What are the storage conditions for 5 + -mercury-6 + -cyanide-3 + -arsenic?
Mercury is a liquid metal, volatile at room temperature, and highly toxic. It should be stored in a sealed container to prevent mercury vapor from escaping. To reduce volatilization, a layer of water can be covered on the surface of the mercury liquid and placed in a cool, ventilated and temperature-stable place, away from fire, heat and strong oxidants. Because mercury and some metals can easily form amalgam, the material of the storage container should also be paid attention to to avoid the use of metal materials that react with mercury.
Cyanide, mostly in solid form, is extremely toxic. It should be stored in a dry and well-ventilated place to prevent moisture. Sealed packaging should be used to prevent cyanide from absorbing moisture in the air and deliquescence. Because acid can produce highly toxic hydrogen cyanide gas, it must be stored separately from acid substances, and the storage area should be clearly marked with warning signs, and personnel should be strictly controlled to enter and exit to prevent accidental touch and misuse.
Arsenic, often in the form of compounds, is also toxic. It should be placed in a dry environment to avoid moisture, because some compounds may undergo chemical reactions after moisture. Storage containers should be well sealed to prevent leakage of arsenic compounds. At the same time, they should be stored separately from food, medicine, etc., away from living areas, to ensure that the storage place has good ventilation and emergency treatment facilities to prevent accidental leakage.