5-BROMO-6-CHLORO-3-AMINOPYRIDINE

5-Bromo-6-chloro-3-aminopyridine is one of the most important intermediates in organic synthesis. It has a wide range of uses and is often a key starting material for the creation of new drugs in the field of medicinal chemistry. Due to its special structure, it can undergo various chemical reactions to construct molecular structures with specific biological activities, helping to develop drugs for various diseases, such as anti-tumor, anti-infection, and neurological diseases.
It also plays an important role in the field of pesticide chemistry. It can be used as a basic raw material for the synthesis of highly efficient, low-toxic and environmentally friendly pesticides. By modifying its structure, compounds with excellent insecticidal, bactericidal or herbicidal properties can be derived, making great contributions to the sustainable development of agriculture.
Furthermore, in the field of materials science, 5-bromo-6-chloro-3-aminopyridine has also emerged. It can participate in the preparation of functional organic materials, such as photovoltaic materials. By ingeniously designing reactions, it is integrated into the material structure, giving the material unique photoelectric properties, and is used in cutting-edge technologies such as organic Light Emitting Diode and solar cells.
In summary, 5-bromo-6-chloro-3-aminopyridine plays an indispensable role in many fields such as medicine, pesticides, and materials science, and is of great significance to promoting progress in related fields.

5-Bromo-6-chloro-3-aminopyridine is an organic compound. Its physical properties are unique and chemically active.
In terms of its physical properties, 5-bromo-6-chloro-3-aminopyridine is often in a solid state or in the form of a crystalline powder at room temperature and pressure, and its appearance may be white to light yellow. The melting point of this compound has been determined to be about 130 ° C to 135 ° C. Within this temperature range, the substance gradually melts from solid to liquid. Its boiling point is relatively high, and at about 300 ° C, the compound begins to transform from liquid to gas.
Furthermore, 5-bromo-6-chloro-3-aminopyridine exhibits a certain solubility in common organic solvents such as ethanol and dichloromethane, but has little solubility in water. This property is related to the bromine, chlorine atoms and amino groups contained in the molecular structure. Bromine and chlorine atoms are halogen atoms and have certain hydrophobicity, while amino groups have certain hydrophilicity, but the hydrophobicity of the overall molecular structure is still dominant, so it has poor solubility in water and better solubility in organic solvents.
In addition, the density of the compound is about 1.8 g/cm ³, which is relatively high, which is related to the halogen atoms contained in the molecule. The relative atomic weight of the halogen atoms is large, resulting in an increase in the overall molecular weight and then the density.
The physical properties of 5-bromo-6-chloro-3-aminopyridine are of great significance for its application in chemical synthesis, drug development and other fields. Understanding its melting point and boiling point is helpful to select suitable temperature conditions during synthesis and purification; and the mastery of solubility is convenient to select suitable reaction solvents to promote the smooth progress of the reaction.

The synthesis method of 5-bromo-6-chloro-3-aminopyridine has been studied by many people in the past. One method is to take the corresponding pyridine derivative first, such as pyridine containing appropriate substituents as the starting material. After halogenation, bromine and chlorine atoms can be introduced. If a suitable halogenation reagent is used, under suitable reaction conditions, a specific position on the pyridine ring can be halogenated. The control of reaction conditions, such as temperature, solvent, catalyst, etc., is essential. If the temperature is too high or too low, the reaction can be deviated; the nature of the solvent is related to the reaction rate and selectivity; the choice of catalyst can also change the chemical process. < Br >
Wait until the halogenation is completed, and then seek the introduction of amino groups. It can be reacted by nucleophilic substitution. Use an amino-based reagent to interact with the halogenated pyridine derivative. However, it is also necessary to pay attention to the reaction conditions, such as the proportion of the reactants. If the proportion is improper, it may cause side reactions to produce and the product is impure. And the acidity and alkalinity of the reaction environment also have a great influence on the reaction. Peracid or perbase can be a bad reaction path.
There are other methods, or introduce amino groups first and then halogenate. However, the effect of each step of the reaction on the existing substituents on the pyridine ring needs to be carefully considered to prevent accidental changes and undesired products. After each step of the reaction, it is necessary to make good use of separation and purification techniques, such as column chromatography, recrystallization, etc., to obtain pure products before providing good materials for the next step of the reaction. Such various synthesis methods have their own advantages and disadvantages, all of which depend on proper selection and fine control to achieve the purpose of synthesizing 5-bromo-6-chloro-3-aminopyridine.

5-Bromo-6-chloro-3-aminopyridine is an important organic compound, and many key points need to be paid attention to when storing.
First environmental factors. It should be stored in a cool place, because high temperature can easily cause its chemical properties to change, or even cause reactions such as decomposition. This compound is quite sensitive to temperature, and high temperature or molecular structure damage, which affects its quality and utility. And the storage environment should be kept dry. Moisture or moisture will make the substance damp, which may cause adverse chemical reactions such as hydrolysis, greatly reducing its purity and stability. For example, if placed in a high humidity environment, moisture may interact with some active parts of the molecule and destroy the original structure.
Furthermore, attention should be paid to the storage container. Corrosion-resistant materials should be selected, such as glass or specific plastic containers. Because it contains halogen atoms such as bromine and chlorine, it has certain chemical activity, or reacts with ordinary metal containers, corroding the container and causing product deterioration. Glass containers are chemically stable and can effectively avoid such problems.
In addition, the storage place should be well ventilated. If the storage space is not well ventilated, the volatile gaseous substances or accumulation of the compound may not only increase the safety risk, but also cause its own reaction due to high local concentration, endangering storage safety.
Also avoid contact with incompatible substances. 5-Bromo-6-chloro-3-aminopyridine contains amino and halogen atoms, has high chemical activity, and is easy to react violently with strong oxidants, strong acids, and strong bases. Therefore, it is necessary to store it separately from these substances to prevent accidental reactions.
In short, proper storage of 5-bromo-6-chloro-3-aminopyridine requires various aspects such as environment, container, ventilation, and material compatibility to ensure its quality and stability, and avoid safety accidents and product deterioration.

5-Bromo-6-chloro-3-aminopyridine, an important organic compound in the field of fine chemicals, is widely used in many industries such as medicine, pesticides, materials, etc. However, its market price range is difficult to say exactly, because many factors can affect it.
The first to bear the brunt is the cost of raw materials. The synthesis of 5-bromo-6-chloro-3-aminopyridine often requires raw materials such as bromide, chloride and pyridine, and the price fluctuation of these raw materials will directly affect the product cost. If the supply of raw materials is tight, or the market demand increases sharply, the price of 5-bromo-6-chloro-3-aminopyridine will also rise, and the market price will rise.
The difficulty and advanced level of the production process are also key factors. If the process is complicated and the equipment and technical requirements are quite high, the production cost will naturally remain high, and the product price will also increase accordingly. On the contrary, if more advanced, efficient and low-cost processes are available, the price of the product may be reduced.
The market supply and demand situation also affects its price. If the downstream industries such as pharmaceuticals and pesticides have strong demand for 5-bromo-6-chloro-3-aminopyridine, but the supply is relatively insufficient, the price will have an incentive to rise; conversely, if the market demand is weak and the supply is excessive, the price will easily decline.
Regional differences should not be underestimated. Production costs, transportation costs, and the degree of market competition in different regions are different, which will also make prices different. In economically developed regions, product prices may be higher due to high labor costs and site rents; while in some places with resource advantages or industrial clusters, prices may be relatively low due to cost advantages.
Overall, the market price of 5-bromo-6-chloro-3-aminopyridine may range from tens to hundreds of yuan per kilogram, which is only a rough range, and the actual price may vary significantly due to changes in the above factors. If buyers want to know the exact price, they should communicate with relevant suppliers in detail and combine the current market situation to obtain accurate price information.