5 Bromo 3 Hydroxy 2 Aminopyridine
pyridine pyrrole pyrazine piperidine piperazine

5-bromo-3-hydroxy-2-aminopyridine

    Specifications

    HS Code

    913460

    Chemical Formula C5H5BrN2O
    Molecular Weight 189.01 g/mol
    Appearance Solid (usually off - white to light yellow)
    Solubility In Water Poor solubility
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Melting Point 160 - 165 °C (approximate, can vary)
    Boiling Point Decomposes before boiling
    Pka The amino group pKa around 4 - 5 (approximate, for basicity)
    Stability Stable under normal conditions, but sensitive to strong acids, bases, and oxidizing agents
    Hazard Class Irritant, may cause skin, eye, and respiratory tract irritation

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    General Information
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    Frequently Asked Questions

    As a leading 5-bromo-3-hydroxy-2-aminopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 5-bromo-3-hydroxy-2-aminopyridine?
    5-Cyanogen-3-fluoro-2-hydroxypyridine is an organic compound. Its physical properties are as follows:
    Viewed at room temperature and pressure, it is mostly white to light yellow crystalline powder. This appearance feature makes it easy to identify and distinguish from other things.
    Smell, usually without a significant special smell, or only a very weak smell, but this smell is generally not irritating and special, and it is not easy to attract attention.
    Its melting point has been determined by many experiments to be about [X] ° C. The melting point is an inherent characteristic of a substance. Under certain conditions, the temperature at which the compound melts from solid to liquid is relatively fixed. This characteristic is of great significance for its purification, identification and application.
    In terms of solubility, it has a certain solubility in common organic solvents, such as methanol, ethanol, dichloromethane, etc. This characteristic is conducive to the selection of suitable solvents in the chemical synthesis and preparation process to help the reaction proceed smoothly, or for subsequent separation and purification operations. In water, its solubility is relatively limited. This shows that when it comes to the application of aqueous systems, the dissolution status needs to be carefully considered to prevent affecting the properties of the system and the reaction process.
    Furthermore, the compound has certain stability, and can maintain its own structure and properties stable for a certain period of time under conventional environmental conditions. In case of specific chemical reagents, high temperature, strong light and other conditions, or a chemical reaction occurs, the structure changes. Understanding its stability and controlling the conditions during storage, transportation and use are of great significance to ensure that it participates in various chemical processes in the expected state.
    What are the chemical properties of 5-bromo-3-hydroxy-2-aminopyridine?
    5-Hydroxy-3-furyl-2-hydroxypyridine, its chemical properties are quite unique. This compound is weakly acidic, and its hydroxyl groups can dissociate protons. In alkaline media, it can react with bases to form corresponding salts.
    It has a certain hydrophilicity. The presence of hydroxyl groups and nitrogen atoms on furan and pyridine rings can form hydrogen bonds with water molecules, making it soluble in water.
    Furthermore, the compound has a conjugated system. Because the furan ring is conjugated to the pyridine ring, it has certain stability and exhibits specific optical properties, such as absorption of light of specific wavelengths, with characteristic absorption peaks in the ultraviolet-visible spectrum.
    At the same time, it can undergo electrophilic substitution reaction. Due to the uneven distribution of electron cloud density in the conjugated system, the electron cloud density at specific positions on the furan ring and the pyridine ring is high, and it is vulnerable to attack by electrophilic reagents, such as halogenation, nitrification, sulfonation, etc. The substitution position is affected by the electronic effect of the substituent on the ring.
    Because it contains multiple heteroatoms and unsaturated bonds, it can be used as a ligand to coordinate with metal ions to form complexes. This complex may have unique physical and chemical properties and may have potential applications in catalysis, materials science and other fields.
    In addition, the hydroxyl group of the compound can participate in the esterification reaction, react with organic acids or inorganic acids under appropriate conditions, and form corresponding ester compounds. This reaction can be used to modify its physical and chemical properties and expand its application range.
    What are the main uses of 5-bromo-3-hydroxy-2-aminopyridine?
    The main use of 5-3-furyl-2-oxo-pyridine is its outstanding application in the fields of chemistry, chemistry and materials.
    In the field of chemistry, it can be used as an important ingredient in synthesis. Due to the special chemical properties of the compounds, it can be synthesized in many ways. It is used to create a biologically active molecular skeleton. This starting material can be synthesized from a series of compounds, which can treat specific diseases, such as antibacterial, antiviral and even anti-cancer compounds. For example, careful synthesis of the method can provide new and effective means for the antibacterial treatment of certain resistant bacteria with effective inhibitory effect.
    5-3-furanyl-2-oxo-pyridine also exhibits an important value in the chemical treatment. It can be prepared into a new type of herbicide or herbicide. Due to its properties, it can inhibit the biological macromolecule-specific interaction of crop diseases and diseases, inhibit the growth of diseases and diseases, ensure the healthy growth of crops, and improve the production of crops. For example, the developed compounds based on this compound have good control effects on fungal diseases of crops.
    In the field of materials, this compound can be used to synthesize polymer materials with special properties. It can be used for functional analysis and polymerization, so that the obtained polymer material has special physical and chemical properties, such as good quality, optical properties or properties. For example, the new optical materials synthesized by it can be used in optical devices to improve the performance of devices and inject new vitality into the development of materials science.
    What are the synthesis methods of 5-bromo-3-hydroxy-2-aminopyridine?
    To prepare 5-hydroxyl-3-furyl-2-hydroxyacetone, there are many methods, each with its own advantages and disadvantages, and varies according to the raw materials and conditions. Common ones include the following:
    First, carbohydrates are used as starting materials. Under specific conditions, carbohydrates can be obtained through a series of reactions such as dehydration and rearrangement. This way raw materials are easy to obtain, carbohydrates are widely distributed in nature, and the cost is relatively low. However, the reaction steps are cumbersome and require precise control of reaction conditions, such as temperature, pH, etc. A slight deviation will easily cause side reactions to occur, affecting the purity and yield of the product.
    Second, the organic synthesis method is used to use suitable furan derivatives and carbonyl-containing compounds as raw materials. After condensation, oxidation, reduction and other reaction steps, the target molecular structure is gradually constructed. This method can carry out more precise design and regulation of the reaction, which is expected to improve the purity and yield of the product. However, the choice of raw materials is limited, some furan derivatives are not easy to obtain, and the cost of reagents or catalysts required for the reaction is high, and the requirements for reaction equipment and operation technology are also quite strict.
    Third, biosynthesis is also feasible. With the help of microorganisms or enzymes, specific substrates are converted into 5-hydroxyl-3-furan-2-hydroxyacetone. This method has the advantages of green environmental protection and mild reaction conditions, which can avoid many high-pollution and high-energy-consuming steps in traditional chemical synthesis. However, the biological system is complex, the screening and culture of bacterial species is difficult, the stability and activity of enzymes also need to be properly resolved, and the scale-up production of the biosynthesis process faces many technical challenges.
    There are various methods for preparing 5-hydroxyl-3-furan-2-hydroxyacetone, each with advantages and disadvantages. In practical application, it is necessary to comprehensively consider factors such as raw material cost, reaction conditions, equipment requirements, product purity and yield, and carefully select the appropriate synthesis method.
    What are the precautions for 5-bromo-3-hydroxy-2-aminopyridine during storage and transportation?
    5-Boron-3-nitrogen-2-hydroxypyridine requires careful attention during storage and transportation.
    Temperature and humidity of the first environment. This compound is quite sensitive to changes in temperature and humidity, and high temperature or high humidity environment may cause its properties to change. Under high temperature, it may cause its decomposition and volatilization, which will damage its quality; in high humidity environment, it is easy to absorb water vapor, or cause deliquescence, which will affect its purity and performance. Therefore, when storing, it should be placed in a cool and dry place. The optimal temperature range is about 5 ° C - 25 ° C, and the relative humidity is maintained at 40% - 60%. < Br >
    The second is the packaging material of choice. Due to its active chemical properties, the packaging material must not chemically react with it. Containers made of glass and specific plastics should be used. Glass containers have good chemical stability and can effectively isolate outside air and water vapor; specific plastic containers have good corrosion resistance and sealing. And the packaging must be tight to prevent leakage and avoid contact with air, moisture, etc.
    Furthermore, the transportation process should avoid vibration and collision. Vibration and collision may cause damage to the container, resulting in compound leakage. The transportation vehicle should run smoothly and the container should be properly fixed. At the same time, it should be transported in isolation from other chemicals, because 5-boron-3-nitrogen-2-hydroxypyridine or reacts with certain chemicals can cause danger.
    In addition, whether it is storage or transportation, it must be clearly marked. Label the name, nature, hazard warning and other information of the compound so that relevant personnel can quickly understand its characteristics and take correct measures to prevent accidents when handling.