5 Bromo 2 Tert Butoxycarbonylamino Pyridine
pyridine pyrrole pyrazine piperidine piperazine

5-Bromo-2-(tert-butoxycarbonylamino)pyridine

    Specifications

    HS Code

    599475

    Name 5-Bromo-2-(tert-butoxycarbonylamino)pyridine
    Molecular Formula C10H15BrN2O2
    Molecular Weight 275.14
    Appearance Solid (predicted)
    Boiling Point 355.9°C at 760 mmHg (predicted)
    Melting Point 113 - 115°C
    Flash Point 169.0°C (predicted)
    Density 1.36 g/cm³ (predicted)
    Solubility Soluble in organic solvents like dichloromethane, chloroform
    Purity Typically high - purity products available, e.g., 95%+

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    General Information
    Where to Buy 5-Bromo-2-(tert-butoxycarbonylamino)pyridine in China?
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    Frequently Asked Questions

    As a leading 5-Bromo-2-(tert-butoxycarbonylamino)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the synthesis method of 5-bromo-2- (tert-butoxycarbonylamino) pyridine?
    To prepare 5-hydroxy- 2 - (pyridyloxymethyl) pyridine, the synthesis method is as follows:
    First, pyridine is used as the starting material. After the halogenation reaction, halogen atoms are introduced at specific positions in the pyridine ring. Commonly used halogenating agents, such as phosphorus halide and sulfoxide halide, can convert pyridine into halogenated pyridine. This step requires attention to the reaction conditions, such as temperature and solvent selection, so that the halogen atoms fall precisely in the desired position to ensure the smooth subsequent reaction.
    Next, the prepared halogenated pyridine is reacted with the pyridine derivative containing hydroxymethyl groups. In this reaction, it is necessary to use suitable bases as catalysts, such as potassium carbonate, sodium hydroxide, etc., to promote the nucleophilic substitution reaction between the two. During the reaction, the properties of the solvent are also very critical. Polar aprotic solvents, such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), are often selected to facilitate the reaction, and the halogen atom interacts with the active group of the hydroxymethylpyridine derivative to obtain an intermediate product containing the target structure.
    Afterwards, the intermediate product is oxidized to convert the specific group into a hydroxyl group. In this step of oxidation, suitable oxidizing agents, such as hydrogen peroxide, potassium persulfate, etc., can be selected. However, the amount of oxidant and the reaction conditions need to be carefully regulated to prevent excessive oxidation and damage to the structure of the product. After this oxidation, 5-hydroxy- 2 - (pyridyloxymethyl) pyridine can be obtained.
    Or there are other methods, such as using other active pyridine derivatives as starting materials, through multi-step reactions, the partial structure of the pyridine ring is first constructed, and then the desired 5-hydroxy and 2 - (pyridyloxymethyl) groups are gradually introduced by cyclization and functional group transformation. Specifically, pyridine fragments with specific substituents can be synthesized first, and the fragments can be connected by condensation reaction, and then modified to achieve the synthesis of the target product. Although the steps may be more complicated, in some situations, it may be possible to avoid the difficulties of specific reactions and improve the yield and purity of the product.
    The whole process of synthesis requires detailed analysis and identification of the reaction products at each step. Common methods, such as nuclear magnetic resonance (NMR), mass spectrometry (MS), infrared spectroscopy (IR), etc., to confirm the structure and purity of the product, and according to the analysis results, timely adjustment of the reaction conditions to achieve the best synthesis conditions.
    What are the main uses of 5-bromo-2- (tert-butoxycarbonylamino) pyridine?
    5-% alcohol-2- (furanoxy carbonyl carbamyl) urea, this substance has a wide range of uses. In the field of medicine, it may lay the foundation for the creation of new drugs. Because the compound has a specific chemical structure and activity, by in-depth investigation of its interaction with molecules in organisms, specific drugs for specific diseases may be developed. For example, in the development of anti-tumor drugs, its unique structure can be used to design drugs that can precisely act on tumor cell targets and hinder the proliferation and spread of tumor cells.
    In agriculture, it may be applied to the development of pesticides. With its impact on the physiological mechanisms of harmful organisms, new pesticides with high efficiency, low toxicity and environmental friendliness can be developed. For example, for some crop pests, this compound may interfere with the nervous system or metabolic processes of pests, thus achieving effective control and reducing harm to the environment and non-target organisms.
    In the field of materials science, 5-% alcohol-2- (furanoxy carbonyl carbamoyl) urea also has potential value. Its chemical properties may assist in the synthesis of polymer materials with special properties. For example, by polymerizing with other monomers, materials with good thermal stability, mechanical properties or biocompatibility can be prepared, which have applications in aerospace, biomedical engineering and many other fields, such as the manufacture of parts for aerospace vehicles, or biomaterials for human tissue repair.
    What are the physical properties of 5-bromo-2- (tert-butoxycarbonylamino) pyridine?
    5-% mercury-2- (acetamidophenoxy) pyridine is an organometallic compound, which has both the characteristics of metallic mercury and the properties of organic ligands, and its physical properties are very interesting.
    Looking at its appearance, it usually takes a solid form under normal conditions, and the texture may be crystalline. Due to the structure of organic ligands, the molecular arrangement is formed, and then crystallization is formed.
    In terms of melting point, due to the chemical bonding between mercury and organic ligands and the interaction force between molecules, its melting point is in a specific range. The electron cloud distribution and spatial structure of organic ligands affect the electronic environment around mercury ions, resulting in the melting point of this compound being different from that of pure mercury metal or ordinary organic compounds. < Br >
    The solubility is quite unique. In organic solvents, such as common toluene and dichloromethane, it exhibits a certain solubility due to the lipophilicity of organic ligands. However, due to the existence of mercury atoms, its solubility in water is not good, because many mercury compounds are hydrophobic, and it is difficult to form effective interactions between water molecules and the compound.
    As for the density, due to the large relative atomic weight of mercury atoms, the density of this compound is higher than that of many common organic compounds. The proportion of mercury atoms in the molecular structure has a significant impact on the overall density.
    The dispersion force, dipole-dipole force, and hydrogen bond forces of 5-% mercury-2- (acetamidophenoxy) pyridine are influenced by the structure of organic ligands and mercury ions. The polar and non-polar sites of organic ligands determine the type and strength of intermolecular interactions, which have a profound impact on their physical properties, such as melting point and solubility.
    Is 5-Bromo-2- (tert-butoxycarbonylamino) pyridine chemically stable?
    If I look at this "5-%E6%BA%B4-2-%28%E5%8F%94%E4%B8%81%E6%B0%A7%E7%BE%B0%E5%9F%BA%E6%B0%A8%E5%9F%BA%29" thing, in order to check whether its chemical properties are stable, it is necessary to study its composition and structure in detail.
    The stability of the chemical properties of the husband depends on the strength of the chemical bonds in the molecule. If the chemical bond energy is high and the atoms are closely bound, the properties are relatively stable; on the contrary, if the chemical bond is easy to break and it is easy to change in case of foreign objects, the properties are unstable.
    This substance is related to both "% E6% BA% B4" and contains "%E5%8F%94%E4%B8%81%E6%B0%A7%E7%BE%B0%E5%9F%BA%E6%B0%A8%E5%9F%BA" and other groups. In the ether group, although the carbon-oxygen bond has a certain strength, the oxygen atom has a lone pair electron, or can interact with electrophilic reagents. And the hydroxyl group, the hydrogen-oxygen bond is polar, hydrogen is easy to dissociate, and can participate in many reactions, such as esterification, acid-base neutralization, etc.
    Looking at this structure, the existence of the hydroxyl group may make this substance show activity under specific conditions. In case of acid, the hydroxyl group can be protonated to enhance its electrophilicity; in case of alkali, the hydroxyl hydrogen can be captured, triggering subsequent reactions. And the ether group is adjacent to the hydroxyl group, and the two may affect each other, changing the distribution of the electron cloud and further affecting the chemical properties. Therefore, according to its structure, the chemical properties of this "5-%E6%BA%B4-2-%28%E5%8F%94%E4%B8%81%E6%B0%A7%E7%BE%B0%E5%9F%BA%E6%B0%A8%E5%9F%BA%29" may not be very stable, and under suitable acid-base environment, temperature and other conditions, it may be prone to chemical changes. However, the accuracy still needs to be verified by experiments before it can be determined.
    What is the price range of 5-bromo-2- (tert-butoxycarbonylamino) pyridine in the market?
    Nowadays, there is five-nitrate two (hydroxyaminohydroxyl), and I want to know its price in the market. In the market, prices often change due to the quality, the time, and the place, so it is difficult to determine the exact number.
    However, roughly speaking, if the quality of five-nitrate is pure and non-miscellaneous, and it is properly harvested, in the city of Dayi, the price may be between tens and hundreds of gold. If it is located in a remote place, or due to supply and demand, the price may rise or fall.
    As for two (hydroxyaminohydroxyl), this substance is relatively rare, and its preparation method is also complicated. If it is of high quality, in a busy commercial port, the price per dose may reach hundreds or even hundreds of gold. However, if you are located in a remote town and there are few applicants, the price may be slightly reduced.
    When the market changes, merchants often offer a large quantity and a good price. If the buyer wants a large quantity, they may be able to get a cheaper price under negotiation. And the market is fickle, and the market changes rapidly. Today's price may vary tomorrow. To know the real-time price, you need to go to the city in person and consult the store before you can get its details.