5-bromo-2-methyl-3aH-2l4-pyrazolo[3,4-b]pyridine

5-Bromo-2-methyl-3aH-2,4-pyrazolo [3,4-b] pyridine is an organic compound. It has a wide range of uses and is mostly used as a key intermediate in the synthesis of drugs in the field of medicinal chemistry.
According to the research and development of Guanfu Medicine, this compound can be integrated into the molecular structure of the drug through specific reaction steps to endow the drug with unique biological activity. For example, in the synthesis path of some innovative drugs targeting specific disease targets, 5-bromo-2-methyl-3aH-2,4-pyrazolo [3,4-b] pyridine can be used as the core skeleton. By modifying and expanding its functional groups, drug molecules with high affinity to the target can be constructed, thereby achieving precise treatment of diseases.
In the field of materials science, it also shows potential uses. Due to its unique molecular structure and electronic properties, it may participate in the preparation of materials with special photoelectric properties. For example, in the exploration of organic Light Emitting Diode (OLED) materials, the introduction of this compound may optimize the luminous efficiency and stability of the material, adding to the progress of display technology.
In addition, in the field of pesticide chemistry, it also has its uses. New pesticides can be designed and synthesized based on this compound, and with its specific chemical structure, it can inhibit or kill certain pests or bacteria, and compared with traditional pesticides, it may have higher selectivity and lower environmental toxicity, which is in line with the needs of the development of green agriculture.

The synthesis method of 5-bromo-2-methyl-3aH-2,4-pyrazolo [3,4-b] pyridine has been known for a long time, and it has been circulating with the years. Many parties have their own wonderful methods, and now it is the way for you.
One method is also based on specific pyridine derivatives, supplemented by brominating reagents, through delicate reactions, bromine atoms are introduced. This bromination step requires careful control of the reaction conditions, such as temperature, reagent dosage, and reaction time. If the temperature is too high, side reactions may occur, resulting in impure products; if it is too low, the reaction will be slow and time-consuming. After the bromine atom is successfully introduced, the methylation step is followed by an appropriate methylation reagent in a suitable environment to cleverly combine the methyl group with the pyridine derivative to obtain the final target product.
Another method is to use pyrazole compounds as starting materials to construct pyridine rings through multi-step reactions. First, the pyrazole reacts with compounds containing specific functional groups to form a preliminary skeleton, and then through cyclization, the pyridine ring structure is built. This process is like building a delicate pavilion, and each step needs to be meticulous. When constructing the pyridine ring, attention should be paid to the selectivity of the reaction check point to ensure that the pyridine ring is generated in the expected way. After the pyridine ring is formed, bromine atoms and methyl groups are introduced in a timely manner according to the previous method, and the target product is carefully carved.
Furthermore, the method of organometallic catalysis is also a good strategy for synthesizing this compound. The selection of suitable organometallic catalysts can make the reaction path more efficient and accurate. Using metal as the guide prompts the reactants to react in a specific direction, reduces unnecessary side reactions, and improves the yield and purity of the product. This catalytic process requires in-depth consideration of factors such as the type, dosage of catalysts, and the pH of the reaction system in order to maximize its effectiveness and help achieve the synthesis goal.

5-Bromo-2-methyl-3aH-2,4-pyrazolo [3,4-b] pyridine, this is an organic compound. Its physical properties are quite important and are related to many practical applications.
When it comes to appearance, under normal temperature and pressure, it is mostly white to light yellow crystalline powder. This color and morphology are directly recognizable by the naked eye, providing a basis for preliminary cognition of the compound. Whether its color is pure or not, and the degree of powder fineness can reflect its purity and other relevant information.
Melting point is also one of the key physical properties. After many experiments, its melting point is within a specific temperature range. The melting point is of great significance. It is not only an important basis for identifying the compound, but also an indication of its physical state transition under different temperature environments. Knowing the melting point can help to control the state change during heating or cooling, and is a key consideration in many chemical operations such as synthesis and purification.
The solubility of this compound cannot be ignored either. This compound exhibits a certain solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). In dichloromethane, it can be dissolved in a moderate proportion to form a uniform dispersion system. In water, the solubility is relatively poor. Such differences in solubility play a decisive role in the post-treatment of chemical synthesis, separation and purification. By taking advantage of the difference in solubility in different solvents, it can be effectively separated from other impurities to obtain high-purity products.
Furthermore, the density of the compound also has a specific value. The physical property of density, although not as intuitive as melting point and solubility, is of great significance in chemical production, storage and transportation. It determines the quality of the compound in a specific volume, affects the calculation of the feeding amount in the production process, and the selection of storage containers and other practical operations.
In summary, the physical properties such as appearance, melting point, solubility, and density of 5-bromo-2-methyl-3aH-2,4-pyrazolo [3,4-b] pyridine affect its application and research in the field of chemistry from different levels. It is an indispensable consideration in many fields such as organic synthesis and drug development.

5-Bromo-2-methyl-3aH-2,4-pyrazolo [3,4-b] pyridine, this is an organic compound. Its chemical properties are quite unique and have many wonders.
When it comes to physical properties, the appearance of this substance is often solid, mostly white or almost white crystalline powder, its color is pure and simple. Under normal temperature and pressure, it is relatively stable, just like a calm person, holding its state.
In terms of solubility, this substance exhibits a certain solubility in organic solvents, such as common ethanol and dichloromethane, just like fish have their own shelter in water. However, in water, the solubility is quite limited, as if the soil is not suitable.
In terms of chemical activity, the bromine atom in this compound is abnormally active, like an active child, and it is easy to participate in the substitution reaction. It can hug many nucleophilic reagents, undergo nucleophilic substitution, and derive other novel compounds, which is like starting a wonderful chemical journey.
The existence of 2-methyl also affects the distribution of molecular electron clouds, which in turn affects its reactivity and selectivity. Just like on the stage of chemical reactions, it sets a unique performance tone for molecules.
Furthermore, the fused ring structure of pyrazolo [3,4-b] pyridine endows the molecule with a unique conjugate system, which gives the molecule a certain aromaticity. This aromaticity is like a unique charm that affects its chemical stability and reaction path.
This compound is widely used in the field of organic synthesis. It can be used as a key intermediate in the creation of various medicines, pesticides and functional materials. Due to its unique chemical properties, it can pave a path for the creation of new substances.

I don't know what the market price of 5-bromo-2-methyl-3aH-2,4-pyrazolo [3,4-b] pyridine is. This compound is not widely known and common, and its price is determined by many factors.
First, the purity has a great impact. If the purity is extremely high and almost flawless, it will be expensive for high-end applications such as fine scientific research; if the purity is slightly lower, it is only for general basic research or preliminary experiments, and the price should be lower.
Second, the difficulty of preparation is related to the price. If its synthesis requires complicated processes, rare raw materials, and harsh conditions, the cost will increase greatly and the price will be high; if the preparation is relatively simple and the cost is controllable, the price will not be outrageous.
Third, the market supply and demand situation is critical. If many scientific research institutions and enterprises are thirsty for its demand, but the supply is limited, the price will rise; if the demand is low and the supply is sufficient, the price will fall.
Fourth, there are differences in merchants. Different suppliers have different pricing due to different cost accounting, business strategies, and brand positioning. Well-known large enterprises have guaranteed product quality, and the brand premium or price is high; small suppliers may have low-price strategies in order to compete for the market.
In summary, due to the lack of information, it is difficult to determine the price range. To know the exact price, you can consult chemical raw material suppliers, scientific research reagent sales platforms, or inquire at relevant industry exchanges to obtain a more accurate number.