5-Bromo-2-methoxy-4-methyl-3-nitropyridine

5-Bromo-2-methoxy-4-methyl-3-nitropyridine is a crucial compound in the field of organic synthesis. It has a wide range of uses and has significant applications in pharmaceutical chemistry, materials science and other fields.
In the field of pharmaceutical chemistry, such compounds are often used as key intermediates. Due to its unique structure, molecular structures with specific pharmacological activities can be precisely constructed through a series of chemical reactions. For example, it can be modified to develop antibacterial, anti-inflammatory and other drugs. Its specific functional group combination provides the possibility for the design of novel drug molecules, which helps to improve the efficacy and selectivity of drugs.
In the field of materials science, 5-bromo-2-methoxy-4-methyl-3-nitropyridine also plays an important role. It may be involved in the synthesis of polymer materials with special properties, such as materials with unique photoelectric properties. By ingenious chemical synthesis strategies, it can be integrated into the polymer skeleton, which can endow materials with specific electrical and optical properties, and show potential application value in organic light emitting diodes, solar cells and other fields.
In addition, in the research process of organic synthetic chemistry, this compound can be used as an important synthetic building block to expand the structural diversity of organic molecules. Based on its structural characteristics, chemists can construct more complex and diverse organic molecular systems through various reactions, such as nucleophilic substitution and coupling reactions, which contribute to the development of organic synthetic chemistry.

The synthesis of 5-bromo-2-methoxy-4-methyl-3-nitropyridine is a key topic in organic synthetic chemistry. In the past, to obtain this compound, many steps were often required, and each step required delicate design and careful operation.
One method may start with a suitable pyridine derivative and be brominated with a brominating agent. In this process, a good solvent must be selected to make the reaction proceed smoothly, and the reaction temperature and time must be precisely controlled to ensure that the bromine atoms are just right to the target position. After bromination, methoxy groups can be introduced. The common method is to react with halogenated pyridine derivatives by alkoxides, borrowing the mechanism of nucleophilic substitution, so that methoxy groups replace the corresponding halogen atoms.
In addition, the introduction of methyl groups is also an important step. Or use methylation reagents to connect methyl groups to pyridine rings under specific conditions. In this step, attention should be paid to the effect of reaction conditions on other groups on the pyridine ring to prevent side reactions from clumping.
As for the introduction of nitro groups, it is often achieved by a mixed acid system of nitric acid and sulfuric acid. However, the nitrification reaction is quite challenging. Due to the special distribution of electron clouds in the pyridine ring, if the reaction conditions are not appropriate, it is easy to cause the product to be impure or produce polynitro substitutes. Therefore, it is necessary to fine-tune the ratio of mixed acid, reaction temperature and reaction time to make the nitro group fall accurately at the specified position.
Synthesis of this compound requires fine control of the reaction conditions at each step, and the separation and purification of intermediates cannot be ignored. The success of each step is related to the purity and yield of the final product. Only by following chemical principles, careful planning and careful operation can this 5-bromo-2-methoxy-4-methyl-3-nitropyridine be obtained.

5-Bromo-2-methoxy-4-methyl-3-nitropyridine is a compound in the field of organic synthesis. Looking at its molecular structure, it is based on a pyridine ring, and bromine, methoxy, methyl and nitro each occupy a specific position. This structure endows it with unique physical properties.
When it comes to its properties, it may be in a solid state under normal conditions, but it also varies depending on the ambient temperature and humidity. Its melting point and boiling point are of great significance for synthesis and purification. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. Due to the complex intermolecular forces, containing a variety of functional groups, the attractive forces between molecules are different, so the melting point may be in a specific range. After experimental determination, it can be accurately obtained, providing a basis for temperature control during synthesis. In the same way, the boiling point is related to the conditions of gasification of substances. During synthesis, separation and purification can be achieved.
Solubility is also an important physical property. In organic solvents, according to the principle of similar miscibility, because the molecule has a certain polarity, it may have a certain solubility in polar organic solvents such as ethanol and acetone. Polar functional groups interact with solvent molecules to disperse the solute. In non-polar solvents such as n-hexane, the solubility may be extremely low, because the force between the molecule and the non-polar solvent is weak.
In addition, density is also one of the characteristics. Density reflects the mass of the substance per unit volume. Although there is no exact value, it can be speculated from the structure and similar compounds. The relative mass of bromine atoms in the molecule is high, or its density is higher than that of common hydrocarbon compounds. Density differences can be used to separate mixtures when operations such as liquid-liquid separation are involved.
In conclusion, the melting point, boiling point, solubility and density of 5-bromo-2-methoxy-4-methyl-3-nitropyridine are of critical significance for its application in organic synthesis, separation and purification, and related fields.

I think this 5 - Bromo - 2 - methoxy - 4 - methyl - 3 - nitropyridine is an organic chemical substance. However, its market price varies greatly depending on time, place, quality and supply and demand.
In the past, in the era of "Tiangong Kaiwu", there was no sale of this fine chemical, but now it is different from the past. Organic chemistry is prosperous. This compound is widely used, either in pharmaceutical synthesis or as a raw material for material preparation, so its price has attracted much attention.
In the chemical raw material market, if its purity is ordinary, the batch is not large, and the price per gram may be in the tens of yuan. However, if the purity is extremely high, reaching the level of scientific research, and the demand is urgent, the price may soar to hundreds of yuan per gram. If it is a large-scale industrial purchase, due to the large quantity and large bargaining space, the unit price may drop sharply, or to a few yuan to tens of yuan per gram.
Furthermore, the market in different regions, due to the transportation cost and the degree of development of the local chemical industry, the price also varies. In prosperous chemical cities, the supply is sufficient, and the price may be stable; in remote places, the transportation is difficult, the cost is superimposed, and the price is high.
Due to the difficulty of the production process and the fluctuation of raw material prices, the market price of this 5-Bromo-2-methoxy-4-methyl-3-nitropyridine is affected. Therefore, to know the exact price, you must consult the chemical raw material supplier and trading platform in real time to get it.

5-Bromo-2-methoxy-4-methyl-3-nitropyridine is an organic compound, and its storage conditions are quite important, which is related to the stability and purity of the substance. This compound should be stored in a cool, dry and well-ventilated place. Due to high temperature, it is easy to accelerate its chemical reaction, or cause adverse changes such as decomposition; humid environment may cause it to be damp and affect its quality; and poor ventilation, or the accumulation of harmful gases, is also unfavorable to its stability.
Store away from fire and heat sources to prevent danger such as combustion or explosion. This compound has certain chemical activity and can cause violent reactions in case of open flame, hot topic.
At the same time, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to its chemical properties or reaction with the above substances, it may cause deterioration or danger. During storage, sealed packaging should be used to avoid contact with air to prevent oxidation or absorption of moisture, carbon dioxide and other substances in the air.
Storage containers are also required. Appropriate materials, such as glass or specific plastic containers, should be selected to ensure that they do not react with compounds and maintain their stability. Regularly check the stored compounds to see if the packaging is damaged or deteriorated, so as to detect and deal with problems in time to ensure the quality and safety of the compounds. In this way, the purpose of properly preserving 5-bromo-2-methoxy-4-methyl-3-nitropyridine can be achieved.