5 Bromo 2 Dimethylamino Pyridine
pyridine pyrrole pyrazine piperidine piperazine

5-Bromo-2-(dimethylamino)pyridine

    Specifications

    HS Code

    433664

    Name 5-Bromo-2-(dimethylamino)pyridine
    Chemical Formula C7H9BrN2
    Molar Mass 201.064 g/mol
    Appearance Solid (color may vary)
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Melting Point 68 - 72 °C
    Boiling Point 254 - 255 °C
    Pka Data may vary depending on conditions
    Stability Stable under normal conditions but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 5-Bromo-2-(dimethylamino)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-bromo-2- (dimethylamino) pyridine?
    5-N-2- (diethylamino) pentane, its main use has not been explained in "Tiangong Rubber", but it has been deduced from ancient and modern knowledge. This compound is mostly involved in the chemical industry and chemical industry.
    In terms of oil, or can be used in psychoactive oil. Because it contains an amino group, the amino group is rich, which can be reversed into acid and improve the solubility of oil; the amino group can increase the water content of the molecule, helping it to be replaced in biological medicine. This oil can be used to treat mental disorders such as serotonin suppression and coke.
    In the chemical industry, it can be used as a surface-active material. Due to the fact that the molecule contains water-containing alkyl groups and amino groups, as well as hydrophobic pentane groups, it can reduce the surface stress of the liquid, and play a role in washing and emulsifying, so that the oil and water can be dispersed evenly, improving the washing and emulsifying effects.
    may also be used in the synthesis of alkyl. With its active function, it can be used to introduce other functional elements or alkyl elements in multiple steps to synthesize more alkyl compounds, such as polymers, fragrances, alkyl, etc., to expand its application in various fields.
    What are the synthesis methods of 5-bromo-2- (dimethylamino) pyridine?
    To prepare 5-hydroxy- 2 - (dimethylamino) pyridine, there are various methods for its synthesis.
    First, 2-chloropyridine is used as the starting material. First, 2-chloropyridine is reacted with dimethylamine. In this step, appropriate temperature and catalyst are required to promote the nucleophilic substitution of the two to obtain 2 - (dimethylamino) pyridine. Subsequently, hydroxyl groups are introduced at the 5th position of the pyridine ring. 5-Nitro-2 - (dimethylamino) pyridine is often formed by nitration reaction, and then nitrogenated to amino group by reduction, followed by diazotization, and finally hydrolyzed to obtain the target 5-hydroxy- 2 - (dimethylamino) pyridine.
    Second, start with 2-methylpyridine. First oxidize 2-methylpyridine to change the methyl group to a carboxyl group to obtain 2-pyridine carboxylic acid. React with dimethylamine and 2-pyridine carboxylic acid to form an amide. By Hoffman rearrangement reaction, the amide is converted to 2 - (dimethylamino) pyridine. After the 5th position of the pyridine ring, the hydroxyl group is introduced according to the methods of nitrification, reduction, diazotization and hydrolysis described above.
    Third, it can be started from 2 - (dimethylamino) pyridine-5-formaldehyde. The formaldehyde can be oxidized to obtain the corresponding carboxylic acid, and then a series of reactions such as esterification and reduction, and finally 5-hydroxyl-2 - (dimethylamino) pyridine. Each method has advantages and disadvantages. The actual synthesis needs to be selected according to the availability of raw materials, the difficulty of controlling the reaction conditions and the yield.
    What are the physical properties of 5-bromo-2- (dimethylamino) pyridine?
    5-Hydroxy-2- (dimethylamino) pentane, this substance is an organic compound. Its physical properties are quite unique.
    Looking at its appearance, it is mostly colorless to light yellow oily liquid under normal conditions, which is easy to observe and identify. In terms of odor, it often emits a special and irritating odor, which can be distinguished by smell.
    When it comes to solubility, it exhibits a certain solubility in water. Due to the presence of polar groups in the molecule, it can interact with water molecules and has better solubility in organic solvents. Organic solvents such as common ethanol and ether can be well miscible with it. This property makes it possible to achieve uniform dispersion and reaction in specific solvent systems in chemical experiments and industrial production. < Br >
    In terms of boiling point, it is in a relatively moderate temperature range. This boiling point value ensures that it can realize the gas-liquid phase transition under specific temperature conditions, which is of great significance to the control of its separation, purification and reaction conditions. The melting point is in a lower temperature range, resulting in the maintenance of liquid state in a normal temperature environment, which greatly facilitates practical operation and application.
    In terms of density, it is slightly lighter than water. In operating scenarios such as liquid-liquid separation, this density characteristic provides the basis and convenience for the separation process. In addition, the substance has a certain volatility. In an open environment, it will slowly evaporate into the air. Special attention should be paid during operation.
    In summary, the physical properties of 5-hydroxy-2- (dimethylamino) pentane lay the foundation for its application in many fields, but the operation process also needs to fully consider its characteristics to ensure safety and efficiency.
    What are the precautions for storing and transporting 5-bromo-2- (dimethylamino) pyridine?
    The five-second (dimethylamino) alkane, when it is in storage, should not be ignored.
    The first word is to hide, this is the most important thing. One, pass the good things. Its nature or fear, if it is in a high environment, it may cause its nature to be easy or dangerous. And it is appropriate to reduce the source of fire and smoke, in order to prevent accidental ignition and formation of large oil. Where it is hidden, its container should also be sealed, otherwise it will be easy to react to the materials in the air, resulting in its composition and efficiency. Furthermore, it is suitable for storage to be dry, and if it encounters moisture or hydrolyzes, it will also be used.
    As for the environment, there is also a general study. The equipment of the warehouse must be stained, and it can withstand the rot of this warehouse. When it is not sealed well, it must be careful to prevent it from falling or colliding. If the equipment is not well sealed, it will not only be rough on the way, but also endanger the safety of the surrounding environment and people and animals. People are also affected by, their nature and danger, and they will know how to do it when they encounter accidents.
    What is the market price of 5-bromo-2- (dimethylamino) pyridine?
    5-Hydroxy-2- (dimethylamino) benzaldehyde, what is the market price? This is related to chemical products, and its price often changes for many reasons.
    First, it is about its quality. If the quality is high, pure and less miscellaneous, it can be applied to high-end fields such as fine chemicals and pharmaceutical research and development, and the price is high. If the quality is normal, it is only used for general industrial use, and the price is slightly lower.
    Second, the supply and demand of the city determines the price. If the city has a strong demand for this product, but there are few producers, the supply is in short supply, and the price will rise. On the contrary, if there are many producers, but there are few people in need, and the supply exceeds the demand, the price will tend to decline.
    Third, the price of raw materials also has an impact. If the price of raw materials increases and the production cost increases, the market price will also increase accordingly. If the price of raw materials decreases, the cost decreases, and the price may also decrease.
    Fourth, the price varies depending on the region. In places where the chemical industry gathers, the price may be relatively low due to the convenience of transportation and competition. In remote places, the transportation cost is high, and the price may be higher.
    In short, the market price of 5-hydroxy- 2- (dimethylamino) benzaldehyde is not fixed and often fluctuates due to factors such as quality, supply and demand, raw material prices, and geography. To know its exact price, it is necessary to study the current market conditions in detail.