5 Bromo 2 Chloropyridine
pyridine pyrrole pyrazine piperidine piperazine

5-Bromo-2-chloropyridine

    Specifications

    HS Code

    532151

    Chemical Formula C5H3BrClN
    Molecular Weight 192.44
    Appearance Solid (usually a white to off - white powder)
    Boiling Point Approximately 220 - 222 °C
    Melting Point 43 - 45 °C
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Purity Typical Commercial Grade Often 95%+
    Odor May have a characteristic halogenated - organic odor
    Stability Stable under normal conditions but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 5-Bromo-2-chloropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 5-bromo-2-chloropyridine?
    5-Nirvana, 2-Nirvana to its material nature, is the unique sexual characteristics of the material, which can be known by the senses or by the senses, and can be maintained under specific conditions.

    According to the solution of the "Text", it means to remove and clear, and it also has a deep meaning. However, in this case, it can be used to create a material. Its material nature or flow. If the liquid thing has a certain viscosity, this viscosity determines the ease of its flow. Its color is clear or clear, or it is other because of its content. Smell it, or have a faint smell, or taste. As for the density, it may be different from water. If the density is higher than water, it sinks in the water; if it is smaller than water, it floats on the water.
    Nirvana, the original meaning of the name of the object, that is, black mud, also means dyeing black. As an object, if it is solid, its shape may not be stale, or it may be scattered, or it may be dense due to factors such as force. Its color is usually black, which is characteristic of its design. Feeling or roughness, because it contains many particles. Its hardness or phase is low, and it is easy to leave marks when it is hard. In addition, if Nirvana encounters water, it may have a certain amount of water absorption, which increases its own weight and changes its shape.
    Therefore, the materiality of 5-Nirvana and 2-Nirvana is determined by their own formation and environment, and such properties also make use of the materiality of these two.
    What are the chemical properties of 5-bromo-2-chloropyridine?
    Mercury is the only metal that is liquid at room temperature. It has many unique chemical properties:
    First, active metal activity. Although mercury is less active than many common metals, it can also react with some substances. For example, mercury can quickly combine with sulfur powder to form mercury sulfide. This reaction is extremely sensitive, so if mercury is accidentally sprinkled in the laboratory, it is often treated with sulfur powder to prevent mercury volatilization and poisoning. The chemical reaction equation is: $Hg + S = HgS $.
    Second, it is easy to form amalgam. Mercury can form an alloy with most metals, which is called an amalgam. If mercury is fused with zinc, zinc amalgam can be obtained. The formation of amalgam often changes the physical and chemical properties of metals, and is widely used in metallurgy and dentistry. In the past, silver amalgam used for dental fillings was an amalgam of metals such as mercury and silver, which was easy to shape and strong after curing.
    Third, there are various compounds. Mercury can form a variety of compounds, common ones are mercury oxide, mercury chloride, etc. Mercury oxide is easily decomposed by heat to form mercury and oxygen. This is an important reaction when Lavoisier studies the composition of air. Its chemical equation is: $2HgO\ stackrel {\ Delta }{=\!=\!=} 2 Hg + O_ {2}\ uparrow $. Mercury chloride, on the other hand, is toxic and has applications in chemical analysis and the preparation of certain drugs.
    Fourth, volatility and toxicity related properties. Mercury is volatile to a certain extent and its vapor is highly toxic. This property causes mercury to be used and stored with extreme caution. The toxicity of mercury stems from its ability to bind to the thiol groups of proteins and enzymes in organisms, interfering with the normal metabolism and function of cells, and damaging the nervous system, kidneys and other organs.
    Mercury has unique chemical properties and has important applications in many fields. However, due to its toxicity, strict safety regulations must be followed when using it to prevent harm to human health and the environment.
    What are the main uses of 5-bromo-2-chloropyridine?
    5 -, 2 - The main users of the metal are metal tools, metal tools and stone, and they are also essential for people's livelihood.
    In the hardware, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, metal, etc., are all used in the smelting of fire, so that they can become useful tools. And 5 -, 2 - gold, just with the help of fire, its contribution cannot be made.
    In the past, the king made tools to benefit the world. In the smelting of metal, 5 -, 2 - put in, can make the hardware of the land uniform, durable. For example, if you add these two, the blade will be sharp, and the cut will be like mud. The tripod, the tripod, is thick and heavy, and can bear a large weight.
    As for the way of cultivation, it is also used very much. In ancient times, the stone and stone were used to treat the people's diseases. 5 - and 2 - have special properties, which can help the force, or the stone and the stone, so that they can be combined. Some alchemy systems are indispensable to these two, in order to prolong the years and benefit, and to remove diseases and evil spirits.
    And the daily life of the people, the manufacture of such equipment, can be used in 5 - and 2 -. The equipment of the artisan can make the cultivation more effective; the equipment of the craftsman can help the excellent technology. Therefore, 5 and 2 are essential for the prosperity of the world and the safety of people's livelihood.
    What are the synthesis methods of 5-bromo-2-chloropyridine?
    The synthesis method of 5-bromo-2-iodoanisole covers various pathways. First, it is based on the nucleophilic substitution reaction of halogenated aromatics. Select a suitable halogenated anisole, such as 2-methoxy-5-halogenated bromobenzene, and an iodizing reagent, such as potassium iodide, in a suitable solvent, such as dimethylformamide (DMF), add a catalyst, such as cuprous iodide and ligand, under heating conditions, through nucleophilic substitution, the halogen atom is replaced by an iodine atom, and the target product can be obtained.
    Second, through the coupling reaction of aryl boric acid. First, 5-bromo-2-methoxyphenylboronic acid is prepared, which can be hydrolyzed from the corresponding halogen by lithium halogen exchange and reaction with borate ester. Then, it is coupled with an iodine-substituted reagent under the catalysis of a palladium catalyst such as tetra (triphenylphosphine) palladium (0) in an alkaline environment, such as an aqueous solution of potassium carbonate mixed with an organic solvent, in order to achieve the purpose of synthesis.
    Furthermore, the direct halogenation strategy of aromatic hydrocarbons is used. Taking anisole as the starting material, first, a brominating reagent such as liquid bromine and a catalyst such as iron powder are brominated to introduce bromine atoms at specific positions of the phenyl ring to obtain 5-bromoanisole. Then, under specific conditions, such as light or heat, and in the presence of an initiator, iodine atoms are introduced to obtain 5-bromo-2-iodoanisole. Each method has its own advantages and disadvantages, and it is necessary to choose the best one according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the requirements of yield and purity.
    What are the precautions for 5-bromo-2-chloropyridine during storage and transportation?
    5% mercury - 2% radon requires careful attention during storage and transportation.
    Mercury is in the state of liquid metal at room temperature, which is volatile and highly toxic. When storing, the first heavy seal. It must be stored in a special container to ensure that there is no gap that can cause mercury to escape. Because once mercury vapor leaks into the air, human inhalation can easily cause mercury poisoning, damaging the nervous system, kidneys and other organs. Container materials are also particular, and it is appropriate to use strong and non-chemical reactions with mercury, such as specific metals or glass materials. Furthermore, the storage place should be cool, dry and well ventilated, protected from high temperature and direct sunlight, to prevent mercury from evaporating rapidly due to rising temperatures.
    When transporting mercury, the packaging must be stable. In addition to sealing the container, it should also be placed in a strong outer package and filled with buffer material to prevent the container from breaking due to collision during transportation. Transport personnel need to be professionally trained and familiar with the characteristics of mercury and emergency treatment methods. Transportation vehicles should also be equipped with corresponding emergency equipment and protective equipment.
    Radon is a radioactive gas, which is colorless and odorless. When storing radon gas, the container used should be able to effectively block its radioactivity. The container material should have good shielding properties, such as lead containers. Storage space should be kept away from crowded areas and living areas, with obvious radioactive warning signs. At the same time, the concentration of radon gas in the storage environment should be regularly tested to prevent leakage.
    When transporting radon gas, it is necessary to follow strict regulations for the transportation of radioactive materials. The means of transportation should have perfect shielding and security measures to ensure that radon gas does not leak during transportation and radioactivity does not endanger public safety. The transportation route should be planned to avoid densely populated areas, and the transportation time should be carefully arranged to minimize the potential impact on the public. And the whole transportation process needs to be strictly supervised and recorded for traceability.