5-Bromo-2-chloropyridine-3-carboxamide

5-Bromo-2-chloropyridine-3-formamide, this is an organic compound with specific chemical properties.
In terms of its physical properties, under normal conditions, or as a solid, its melting point, boiling point and other properties are affected by intermolecular forces and structures. In the molecule, halogen atoms such as bromine and chlorine, due to their high electronegativity, change the polarity of the molecule, which plays a role in its melting point and solubility.
In terms of chemical properties, amide groups are one of the important functional groups of this compound. Amids have certain stability, but can also react under specific conditions. For example, in acid or base-catalyzed hydrolysis reactions, amide bonds can be broken to form corresponding acids and amines (or ammonium salts).
And because the pyridine ring is aromatic, its electron cloud distribution is unique, so that the substituents on the pyridine ring participate in various reactions. Halogen atoms, bromine and chlorine, can undergo nucleophilic substitution reactions. If in the presence of appropriate nucleophiles, halogen atoms can be replaced by other groups. This reaction is often used in organic synthesis to introduce new functional groups and build more complex molecular structures.
In addition, the compound may also participate in some reactions related to the pyridine ring, such as the electrophilic substitution reaction on the pyridine ring. Due to the electron cloud density distribution characteristics of the pyridine ring, the reaction check point is different from that of the general benzene ring. These reaction characteristics provide organic synthesis chemists with a variety of strategies to create various organic compounds containing pyridine structures for use in pharmaceutical chemistry, materials science and many other fields.

5-Bromo-2-chloropyridine-3-formamide, which has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of many effective drugs. Geinpyridine ring has a special structure and has good biological activity and pharmacological properties. After modification and transformation, it can be used to prepare various types of drugs such as antibacterial, antiviral and anti-tumor.
In the field of materials science, it also has important applications. It can participate in the preparation of organic materials with unique functions, such as photoelectric materials. After rational design and reaction, it can be introduced into a specific molecular structure, which can endow the material with unique optical and electrical properties. It is used in cutting-edge technologies such as organic Light Emitting Diode and solar cells.
In agricultural chemistry, it can be used as a raw material for the synthesis of highly efficient pesticides. By adjusting its chemical structure, pesticides with high selectivity, low toxicity and environmental friendliness to pests can be developed, which can help improve crop yield and quality, while reducing the harm to the ecological environment.
Because of its structure containing halogen atoms and amide groups, it is chemically active. In the field of organic synthetic chemistry, it is often used as a reactant or catalyst to promote various organic reactions and provide an effective way to construct complex organic molecular structures. In short, 5-bromo-2-chloropyridine-3-formamide is of great value in many fields and promotes technological development and innovation in various fields.

The synthesis of 5-bromo-2-chloropyridine-3-formamide is rather complicated and requires fine operation. It is often started with the corresponding pyridine derivatives. First, take the appropriate pyridine raw materials, and introduce bromine atoms in a specific reaction vessel at a suitable temperature and catalyst. This step requires the selection of brominating reagents, such as liquid bromine or N-bromosuccinimide (NBS), and control the reaction conditions to achieve the desired bromination check point and yield. After the bromination is completed, the bromine-containing pyridine intermediate is obtained through conventional operations such as separation and purification. < Br >
Then chlorine atoms are introduced, and chlorine reagents, such as thionyl chloride or phosphorus oxychloride, are selected according to the reaction characteristics. The reaction environment is adjusted so that the chlorine atoms precisely replace the target position, and then after post-treatment, a pyridine compound containing both bromine and chlorine is obtained.
Finally, a formamide group is constructed, which is often used with carboxyl pyridine derivatives and ammonia or amine reagents in a suitable reaction system or with the assistance of a condensing agent. After the reaction, the pure 5-bromo-2-chloropyridine-3-formamide product is obtained by means of extraction and column chromatography. Each step of the reaction requires strict control of the conditions, paying attention to factors such as the proportion of raw materials, temperature, and reaction time, in order to improve the yield and product purity.

I look at you and ask, but I am inquiring about the market price of 5-bromo-2-chloropyridine-3-formamide. However, the price of this product often varies due to changes in time, land, quality and supply and demand. In the past, its price fluctuated according to many factors such as production process, raw material cost, and market demand.
In the past, if the production process is well-crafted and the cost of raw materials is controllable, the price may be slightly lower. However, if raw materials are scarce or the process is complicated, the price will rise. And if the market demand is strong, the supply is in short supply, and the price will also increase; if the demand is sluggish, the supply exceeds the demand, and the price will drop.
Also, the price varies from place to place. Prosperous city, prosperous business, convenient logistics, or because of competition, the price may be stable. And remote places, due to transportation costs and other reasons, the price may be different.
However, I don't have the exact market price at the moment. If you want to know the details, you can consult the chemical raw material market merchants, or check the chemical product price information platform, or visit the relevant chemical industry forums to communicate with people in the industry to get accurate price information.

5-Bromo-2-chloropyridine-3-formamide is an organic compound. During storage and transportation, the following matters should be paid attention to.
One is the storage temperature. This compound should be stored in a cool place and protected from heat. Due to high temperature, it is easy to change its chemical properties, or cause decomposition and deterioration. Therefore, the storage temperature should be controlled in a refrigerated environment of 2-8 ° C, which can ensure its stability and prolong the storage period.
The second is related to the influence of humidity. Be sure to place it in a dry place, away from water sources and moisture. Because it may be hygroscopic, the quality may be damaged after moisture absorption, and even chemical reactions may occur. Therefore, the storage area needs to have good moisture-proof measures, such as using desiccant to maintain a dry environment.
The third is packaging requirements. The packaging must be tight to prevent contact with the air. Due to oxygen, carbon dioxide and other components in the air, or react with them. It should be packaged in sealed containers, such as glass bottles, plastic bottles, etc., and the packaging materials must be compatible with the compound, and no chemical reaction will occur.
The fourth is transportation safety. During transportation, avoid violent vibration and collision to prevent packaging damage. If the packaging is damaged, the compound will leak, which will not only cause losses, but may also pose a hazard to the environment and personnel. At the same time, the transportation tool needs to maintain suitable temperature and humidity conditions to meet the storage requirements of the compound.
Fifth, the label is clear. Storage and transportation containers should be clearly marked with the name of the compound, properties, hazards and other information. In this way, the staff can take correct protection and operation measures at a glance when handling, and avoid danger due to ignorance.
In short, when storing and transporting 5-bromo-2-chloropyridine-3-formamide, temperature, humidity, packaging, vibration and labeling should not be ignored, so as to ensure its quality and safety.