5 Bromo 1h Pyrrolo 2 3 B Pyridine 2 3 Dione
pyridine pyrrole pyrazine piperidine piperazine

5-bromo-1H-pyrrolo[2,3-b]pyridine-2,3-dione

    Specifications

    HS Code

    505644

    Name 5-bromo-1H-pyrrolo[2,3-b]pyridine-2,3-dione
    Molecular Formula C7H3BrN2O2
    Molecular Weight 227.015 g/mol

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    General Information
    Where to Buy 5-bromo-1H-pyrrolo[2,3-b]pyridine-2,3-dione in China?
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    What are the physical properties of 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione
    5 - bromo - 1H - pyrrolo [2,3 - b] pyridine - 2,3 - dione is an organic compound. Its physical properties are crucial to the performance of this compound in various chemical processes and practical applications.
    Looking at its morphology, under normal temperature and pressure, this substance may be a solid, or it may exhibit a specific crystal form due to the characteristics of intermolecular forces and crystal structures, such as needle-like crystals or powders. The formation of this morphology is closely related to the spatial arrangement and interaction of molecules.
    The melting point is discussed, and its melting point value is determined by the strength of intermolecular forces. The presence of bromine atoms and pyrrolidinedione structures in the molecule affects the intermolecular attraction and makes the melting point have a specific range. This melting point data is crucial for the purification and identification of compounds, and can provide key temperature parameters for experimental operations.
    In terms of solubility, because the molecule contains polar groups, it may have certain solubility in polar solvents such as water and alcohols. However, the presence of bromine atoms may enhance the hydrophobicity of the molecule, resulting in poor solubility in non-polar solvents such as alkane solvents. Its solubility characteristics are a key consideration when separating, extracting and selecting solvents for chemical reactions.
    The density of this substance is also an important physical property. The density is closely related to the molecular weight and the degree of molecular accumulation. Accurately know the density, and can precisely control the dosage when measuring and mixing compounds to ensure the accuracy of experiments and production processes.
    The physical properties of 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione, such as morphology, melting point, solubility, density, etc., are of great significance to its chemical research and practical application, laying the foundation for the operation and exploration of related fields.
    What are the chemical properties of 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione
    5-Bromo-1H-pyrrolido [2,3-b] pyridine-2,3-dione, this is an organic compound. Its chemical properties are unique, let me tell you in detail.
    First of all, its physical properties are at room temperature, or as a solid, with a specific melting point and boiling point. These two are related to its phase transition, which has a great influence on its existence in different temperature environments. The melting point is the critical temperature at which a substance changes from solid to liquid; the boiling point is the critical temperature at which the liquid state changes to gas. Knowing both of these has important guidelines for its separation, purification, storage, etc.
    In addition to its chemical activity, in the molecular structure, bromine atoms are abnormally active. Bromine has strong electronegativity, which makes it easy to leave, and then participates in many nucleophilic substitution reactions. In such reactions, nucleophiles attack bromine atoms to form new compounds. This property makes this substance widely used in the field of organic synthesis, and can be used as an intermediate to construct more complex organic molecules.
    Furthermore, the structure of the two ketones in the molecule should not be underestimated. Diketones have a unique electron cloud distribution and can participate in many reactions related to carbonyl groups. For example, they can condensate with compounds containing active hydrogen to form new carbon-carbon or carbon-heteroatom bonds, thereby expanding the molecular skeleton.
    In addition, its performance in acid-base environments is also considerable. Although it does not have obvious acid-base functional groups, under certain conditions, the diketone structure can be catalyzed by acid and base, and tautomerism occurs, which affects its reactivity and selectivity.
    In summary, 5-bromo-1H-pyrrolido [2,3-b] pyridine-2,3-diketone has unlimited potential in the field of organic synthetic chemistry due to its unique structure and combination of various chemical properties. Researchers can use this to explore new reaction pathways and create new functional materials and drug molecules.
    What is the common synthesis method of 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione
    5 - bromo - 1H - pyrrolo [2,3 - b] pyridine - 2,3 - dione is also an organic compound. Its common synthesis methods probably have several ways.
    First, a compound containing pyridine and pyrrole structures is used as the starting material. First, the pyridine ring and a suitable halogenated reagent, such as a brominating reagent, act under suitable reaction conditions to introduce bromine atoms at a specific location. This bromination process requires fine regulation of the reaction temperature, time and reagent dosage. If the temperature is too high or too long, it may cause excessive halogenation and affect the purity of the product; if the temperature is too low or the time is too short, the bromination reaction will be incomplete.
    Then, for the pyrrole moiety, the diketone structure is constructed through a series of reactions. Or, using carbonyl-containing reagents, under the catalysis of bases or acids, through nucleophilic addition, cyclization and other steps, the skeleton of 1H-pyrrolo [2,3-b] pyridine-2,3-dione is formed. The choice of catalytic conditions is crucial, and different catalysts have a significant impact on the reaction rate and selectivity.
    Second, a more concise small molecule compound is used as the starting point and gradually spliced into the target molecule. The bromine-containing pyridine fragment is first synthesized, and then the pyrrolidinone structure is connected to it through a clever reaction. This process requires a precise grasp of the reactivity check point and a reasonable design of the reaction sequence to avoid unnecessary side reactions.
    Furthermore, in synthesis, the choice of solvent should not be underestimated. The polarity and solubility of different solvents have a great impact on the reaction process. Polar solvents may be conducive to ionic reactions, while non-polar solvents perform better in some free radical reactions. And during the reaction process, monitoring means also need to be complete, such as using thin-layer chromatography, nuclear magnetic resonance and other technologies to monitor the reaction process in real time to ensure that the reaction proceeds in the expected direction to obtain high-purity 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione products.
    Where is 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione used?
    5-Bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione is an organic compound, which has applications in medicine, materials and other fields.
    In the field of medicine, such nitrogen-containing heterocyclic compounds often have unique biological activities. Because of its structural properties, it can be used as a potential drug lead compound. Or it can be modified by its structure to develop anti-tumor drugs. Because the compound structure can bind to specific targets in tumor cells, interfere with tumor cell growth and proliferation-related signaling pathways, and then inhibit the development of tumor cells. Or it can be developed as an antibacterial drug, which interacts with key enzymes or proteins in bacteria to destroy the normal physiological function of bacteria and achieve antibacterial effect.
    In the field of materials, 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione can be used to prepare functional materials. Because of its specific electronic structure and chemical properties, it can participate in material synthesis reactions and endow materials with special properties. For example, introducing it into polymer materials may change the electrical properties of materials, making it suitable for organic electronic devices, such as organic Light Emitting Diodes (OLEDs), organic field effect transistors (OFETs), etc., to improve device performance and stability. Furthermore, in terms of optical materials, the compound or its conjugated structure exhibits unique optical properties, which can be used to prepare fluorescent materials and applied to fields such as fluorescence detection and biological imaging. By means of its fluorescence signal, highly sensitive detection and imaging of specific substances or biomolecules can be achieved.
    What is the market outlook for 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione
    5-Bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione is also an organic compound. To view its prospects in the market, various factors need to be considered in detail.
    The first to bear the brunt, this compound may have considerable potential in the field of medicine. In the way of drug development, its structure may be endowed with unique biological activities and can interact with specific biological targets. If it can be used to explore new anti-tumor drugs, its structural characteristics may interfere with the key metabolic pathways or signal transduction pathways of tumor cells. However, if it is to be used in medicine, it must go through a long process of rigorous pharmacological research and toxicological tests to prove its safety and effectiveness. This process is time-consuming and costly.
    Furthermore, in the field of materials science, there are also things to be explored. Its unique chemical structure may make it stand out in the field of optoelectronic materials. If it can be used to prepare organic Light Emitting Diode (OLED) materials, its molecular structure may affect key properties such as luminous efficiency and color purity. However, in order to achieve industrial application, it is still necessary to overcome many problems such as material stability and preparation process complexity.
    Looking at the market competition situation, if similar structural compounds already occupy the market, it is even more difficult to stand out. A lot of resources need to be invested in R & D and innovation to highlight their own advantages.
    In addition, policy and regulatory factors should not be underestimated. Environmental protection policies are increasingly stringent requirements for the production process of compounds. If the production process does not conform to the concept of green chemistry, or faces the risk of rectification or even shutdown.
    In summary, although 5-bromo-1H-pyrrolo [2,3-b] pyridine-2,3-dione has addressable market opportunities, in the application fields of medicine and materials, it is facing many challenges such as research and development, competition, and regulations. To open up a broad market prospect, it is still necessary to make unremitting efforts and explore.