5 Bromo 1h Pyrazolo 3 4 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

5-Bromo-1H-pyrazolo[3,4-b]pyridine

    Specifications

    HS Code

    906072

    Chemical Formula C6H4BrN3
    Molar Mass 198.02 g/mol
    Appearance Solid (presumably, typical for such organic compounds)
    Melting Point Data may vary, need to refer to specific literature
    Boiling Point Data may vary, need to refer to specific literature
    Solubility In Water Low solubility expected as it's a relatively non - polar organic compound
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Pka Data may vary, need to refer to specific literature for acidic or basic sites
    Density Data may vary, need to refer to specific literature
    Stability Stable under normal conditions but may react with strong oxidizing or reducing agents

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    General Information
    Where to Buy 5-Bromo-1H-pyrazolo[3,4-b]pyridine in China?
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    Frequently Asked Questions

    As a leading 5-Bromo-1H-pyrazolo[3,4-b]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 5-Bromo-1H-pyrazolo [3,4-b] pyridine?
    5 - Bromo - 1H - pyrazolo [3,4 - b] pyridine is an organic compound with a wide range of uses in organic synthesis and medicinal chemistry.
    It is mainly used in drug development. In this field, it is often used as a key intermediate to synthesize compounds with specific biological activities. Due to its unique chemical structure, it can be spliced with other molecular fragments through various chemical reactions to construct molecules with complex structures and potential medicinal value. For example, in the process of creating many new drugs targeting specific disease targets, 5-Bromo-1H-pyrazolo [3,4-b] pyridine is used as a starting material to modify its structure through multi-step reactions to optimize the affinity and selectivity of the drug to the target and improve the efficacy of the drug.
    In the field of materials science, it also has certain applications. With its chemical properties, it can participate in the preparation of materials with special photoelectric properties. By rationally designing the reaction path and introducing it into the molecular structure of the material, the material is endowed with unique properties such as light absorption, emission or charge transport, which shows potential application value in the fabrication of organic Light Emitting Diodes, solar cells and other devices.
    In addition, in the study of organic synthesis methodology, 5-Bromo-1H-pyrazolo [3,4-b] pyridine can be used to explore novel chemical reaction mechanisms and synthesis strategies. Chemists use it as a substrate to study the reactivity and selectivity under different reaction conditions, expand the methods and means of organic synthesis, and provide ideas and methods for the efficient synthesis of more complex organic compounds.
    What are the synthesis methods of 5-Bromo-1H-pyrazolo [3,4-b] pyridine
    5 - Bromo - 1H - pyrazolo [3,4 - b] pyridine is an important organic compound, and its synthesis method is more elegant.
    One of the methods is to use a compound containing a pyridine structure as the starting material. Under suitable reaction conditions, a suitable substituent is introduced into a specific position of the pyridine ring of this starting material. The introduction of this substituent requires precise control of the reaction conditions, such as temperature, reaction time, ratio of reactants, etc. The electron cloud distribution of the Gainpyridine ring is special, and the activity of each position is different. After the substituent is introduced, a specific cyclization reaction is performed to construct a pyrazole ring. In the cyclization reaction, it is crucial to select the appropriate reagent and reaction environment, such as specific bases, solvents, etc., to promote the molecular inner ring to form the basic skeleton of the target compound.
    The second method can start from the compound containing the pyrazole structure. First modify the pyrazole ring and introduce the appropriate group at a specific position to create conditions for the subsequent connection with the pyridine ring. Subsequently, the connection between the two is achieved by reacting with the reagent containing the pyridine fragment. This connection reaction requires fine regulation, such as the use of suitable catalysts, reaction media, etc., to ensure that the reaction selectively occurs at the target location, so that the 5-Bromo-1H-pyrazolo [3,4-b] pyridine can be successfully synthesized.
    Or other related heterocyclic compounds are used as the starting materials, and the structure of the target molecule is gradually constructed through multi-step reactions. Each step of the reaction needs to be strictly controlled, from the optimization of the reaction conditions to the separation and purification of the intermediates, all of which are related to the purity and yield of the final product.
    In short, there are various methods for synthesizing 5-Bromo-1H-pyrazolo [3,4-b] pyridine. Each method has its own advantages and disadvantages. The appropriate synthesis path needs to be carefully selected according to actual needs and conditions.
    What is the market price of 5-Bromo-1H-pyrazolo [3,4-b] pyridine
    What you are asking about is the market price of 5-Bromo-1H-pyrazolo [3,4-b] pyridine. Sadly, the market price of this compound cannot be summarized in a single word. The price of this compound is influenced by many factors.
    The first to bear the brunt is the difficulty of production. If the synthesis process of this compound is complicated, and rare raw materials, special reaction conditions or exquisite technology are required, the production cost will be high and the price will be high. For example, if it needs to be reacted at extreme temperatures, pressures, or using expensive catalysts, it will drive up the cost.
    Furthermore, the supply and demand situation of the market is also critical. If this compound is in strong demand in pharmaceutical research and development, chemical production and other fields, but the supply is limited, the so-called "rare is expensive", its price will rise. On the contrary, if the market is oversupplied, the price will decline.
    In addition, different manufacturers will also lead to price differences. Large factories may control costs due to scale effects, and prices may be competitive; small factories may have high prices due to small output and high costs. And the purity and quality of products from different manufacturers are also different. Those with high quality may have higher prices.
    Also, regional factors cannot be ignored. Prices will vary in different places due to differences in transportation costs, tax policies, etc. For example, in remote places, transportation is inconvenient, costs increase, and prices may be higher than those in convenient transportation.
    To sum up, in order to know the exact market price of 5-Bromo-1H-pyrazolo [3,4-b] pyridine, it is necessary to carefully examine many factors such as production difficulties, supply and demand, manufacturers, and regions in order to make a more accurate judgment.
    What are the physicochemical properties of 5-Bromo-1H-pyrazolo [3,4-b] pyridine?
    5 - Bromo - 1H - pyrazolo [3,4 - b] pyridine is an organic compound, its physicochemical properties are particularly important, and it is widely used in chemical research and related fields.
    In terms of its physical properties, under room temperature and pressure, this substance is mostly in solid form, but the exact physical state may vary according to purity and specific conditions. Its melting point, boiling point and other data are of great significance for identification and separation and purification. It is difficult to obtain accurate values, due to differences in different literature and experimental conditions. Generally speaking, compounds containing such heterocyclic structures have relatively high melting points. This is due to interactions such as hydrogen bonds and van der Waals forces between molecules, which make the molecules tightly bound and require more energy to cause phase state transitions.
    As for chemical properties, bromine atoms in 5-Bromo-1H-pyrazolo [3,4-b] pyridine have high activity. As a halogen element, bromine is electrophilic and easily participates in substitution reactions. For example, under suitable reaction conditions and catalysts, nucleophilic substitution reactions can occur, and bromine atoms are replaced by other nucleophilic reagents, which is an important means to construct new organic compound structures. In addition, the pyrazolopyridine heterocyclic structure it contains also has unique chemical activity. The nitrogen atom in the heterocyclic ring is rich in lone pairs of electrons, which can be used as electron donors, participate in coordination chemistry and other reactions, and form complexes with metal ions, which show potential application value in the field of materials science and catalysis. At the same time, the heterocyclic ring may undergo cyclization, ring opening and other reactions under specific conditions, providing various possibilities for organic synthesis.
    The physicochemical properties of 5-Bromo-1H-pyrazolo [3,4-b] pyridine lay an important position in the fields of organic synthesis, medicinal chemistry and other fields, providing a broad space for related research and applications.
    Where is 5-Bromo-1H-pyrazolo [3,4-b] pyridine used?
    5 - Bromo - 1H - pyrazolo [3,4 - b] pyridine is an organic compound, which has applications in medicine, materials and other fields.
    In the field of medicine, this compound can be used as a key intermediate for the synthesis of new biologically active drug molecules. Due to the unique structure of this compound, it can be combined with specific biological targets to regulate physiological processes in organisms and demonstrate the potential to treat diseases. For example, in the development of anti-tumor drugs, it may participate in the construction of small molecule inhibitors targeting specific proteins of tumor cells, and achieve the purpose of treating tumors by inhibiting the proliferation and migration of tumor cells; in the development of antibacterial drugs, it may be able to design inhibitors targeting specific metabolic pathways or enzymes of bacteria, by interfering with the normal physiological activities of bacteria, to achieve antibacterial effect.
    In the field of materials, 5-Bromo-1H-pyrazolo [3,4-b] pyridine also has important uses. Because of its special electronic structure and chemical properties, it can be used to prepare functional organic materials. For example, in organic optoelectronic materials, it may be used as a construction unit to participate in the synthesis of conjugated polymers or small molecules with excellent optoelectronic properties. Such materials may be applied to organic Light Emitting Diode (OLED), organic solar cells and other devices to improve the luminous efficiency and photoelectric conversion efficiency of the device. And because its structure contains bromine atoms, other functional groups can be introduced through chemical modification to further regulate the properties of the material to meet the needs of different application scenarios.
    5 - Bromo - 1H - pyrazolo [3,4 - b] pyridine plays an important role in the field of medicine and materials, and its application prospects will become broader with the deepening of research.