5-BOC-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE-2-CARBOXYLIC ACID

5-BOC-4,5,6,7-tetrahydropyrazolo [3,2-C] pyridine-2-carboxylic acid, the structure of this compound is composed of specific atomic combinations and connection methods.
Looking at its structure, the "pyrazolo [3,2-C] pyridine" part is the heterocyclic structure of the core. The pyrazole ring and the pyridine ring are connected in a specific fused manner to form a unique cyclic structure. Among them, the pyrazole ring has two adjacent nitrogen atoms, and the pyridine ring contains one nitrogen atom. The interaction between the two gives the molecule a specific electron cloud distribution and chemical activity.
"5-BOC", that is, tert-butoxycarbonyl, is attached to the fifth position of the pyrazolopyridine structure. This group has a large steric barrier, which has a great impact on the physical and chemical properties of compounds, which can enhance the stability of molecules. It is also often used as a protective group in organic synthesis, which is convenient for selective modification of specific functional groups.
and "-2-carboxylic acid" indicate that there is a carboxyl group attached to the second position of the fused ring structure. The carboxyl group is a strong polar functional group, which is acidic and can participate in many chemical reactions, such as salt formation, esterification, etc. The existence of this functional group makes the compound both hydrophilic and affects its solubility, biological activity and interaction with other molecules.
Overall, the chemical structure of 5-BOC-4,5,6,7-tetrahydropyrazolo [3,2-C] pyridine-2-carboxylic acid is related to each other, and together determine its unique chemical and physical properties. It has important research value and application potential in the fields of organic synthesis and medicinal chemistry.

5-BOC-4,5,6,7-tetrahydropyrazolo [3,2-C] pyridine-2-carboxylic acid, this compound has unique physical properties. At room temperature, it mostly exists in a solid state, but its specific appearance may vary depending on the crystallization condition, or it is a white crystalline powder, or a crystal with a certain shape, which is determined by its molecular arrangement and crystallization conditions.
When it comes to the melting point, the melting point of this compound is quite fixed, about a certain temperature range, which is crucial for its identification and purity judgment. The determination of the melting point is an important means to identify the compound. If the purity is high, the melting point range is narrow and similar to the theoretical value; if it contains impurities, the melting point may decrease and the melting range becomes wider.
In terms of solubility, it varies in organic solvents. In polar organic solvents, such as methanol and ethanol, there may be a certain solubility, which is due to the similar compatibility of polarities; in non-polar organic solvents, such as n-hexane and cyclohexane, the solubility may be very small. The solubility in water is also limited, because although the molecular structure contains carboxyl groups that can form hydrogen bonds with water, the overall hydrophobicity also restricts its water solubility.
In addition, the density of the compound is also one of its physical properties, and the density is closely related to the molecular weight and molecular accumulation. Its density data is of great significance for quantitative analysis and operation in solution systems, such as the preparation of specific concentration solutions. And its optical properties such as refractive index can also provide a basis for its identification and analysis under specific research and application scenarios. In short, understanding its physical properties is essential for the synthesis, purification, identification and application of the compound.

The common methods for the synthesis of 5-BOC-4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2-carboxylic acid include the following.
First, a suitable pyridine derivative is used as the starting material. The pyridine ring is selectively hydrogenated to hydrogenate the double bond at the 4,5,6,7 position to obtain the tetrahydropyridine structure. In this step, suitable catalysts, such as metal palladium and platinum, can be used to support activated carbon and react under mild hydrogen pressure and temperature conditions, which can effectively control the degree of hydrogenation. Subsequently, the carboxyl group is introduced into the second position of the pyridine ring, which can be achieved by reacting with suitable carboxylating reagents, such as halogenated carboxylic acid esters reacting with substrates under basic conditions, and then hydrolyzed to obtain the target carboxylic acid.
Second, a cyclization strategy can be adopted. A chain-like compound containing a specific functional group is selected to construct a pyridine ring structure through an intramolecular cyclization reaction. First, a chain-like precursor containing an amino group at one end and a carboxyl group at the other end or its active derivative is prepared. Under appropriate cyclization reagents and reaction conditions, such as in the presence of a shrinking agent, the pyridine [3,2-C] pyridine structure is formed through the molecular inner ring. Then, the amino group of the obtained product is protected by BOC and treated with tert-butoxycarbonylation reagent to obtain 5-BOC-4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2-carboxylic acid.
Third, use a combination of multi-step reactions. Starting from simple raw materials, gradually build each part of the target molecule. For example, first synthesize a pyridine ring fragment, and then react with a suitable alkenyl or alkynyl-containing fragment through a series of reactions such as addition and cyclization to form a pyridine ring and a tetrahydro structure. Finally, the introduction of carboxyl groups and BOC protecting groups is carried out to complete the synthesis of the target product. Each step requires precise control of the reaction conditions to ensure the purity and yield of the product.

5-BOC-4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2-carboxylic acid, which is used in the fields of pharmaceutical creation, organic synthesis and chemical raw materials.
In the field of pharmaceutical creation, it is very important. Due to its unique structure, it can be used as a key intermediate to prepare a variety of biologically active compounds. In the process of many drug development, based on this, through clever derivatization reactions, molecules that closely fit specific biological targets can be constructed, thus paving the way for the birth of new drugs. For example, in the exploration of drugs for the treatment of neurological diseases, by virtue of its structural properties, drugs with precise effects on neurotransmitter regulation may be created to help relieve diseases.
In the field of organic synthesis, it is an important building block. Chemists can use its functional group properties to build complex organic molecular structures through various organic reactions, such as nucleophilic substitution, redox, etc. This provides the possibility for the synthesis of natural products or organic materials with special functions. For example, when synthesizing organic materials with optical activity, it can be used as a starting material, which can be reacted in multiple steps to endow the material with unique photoelectric properties.
In the field of chemical raw materials, it is also indispensable. As a basic raw material, it can produce a variety of industrial chemicals through a series of chemical transformations. These chemicals are either used in the production of plastics, rubber additives, etc., to improve material properties, or used in the preparation of coatings, adhesives and other products to broaden the application range of chemical products.
Therefore, 5-BOC-4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2-carboxylic acid plays a key role in many scientific and industrial fields, and has made great contributions to promoting progress in related fields.

There is a question today about the market price of 5-BOC-4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2-carboxylic acid. This compound is often a key intermediate in the field of organic synthesis, and has important applications in the fields of pharmaceutical chemistry and materials science.
However, its market price is difficult to determine. The price of this compound is affected by many factors. The first one to bear the brunt is the difficulty of preparation. The synthesis process of this compound may require multiple steps of reaction, and the reaction conditions are strict. If the synthesis process is difficult, the raw materials are rare, the cost is high, and its price is also high.
Furthermore, the market supply and demand situation is also the key. If there is a large increase in demand for this product in industries such as pharmaceutical research and development, and the supply is limited, the price will rise; conversely, if the market is saturated and the supply exceeds the demand, the price will decline.
Repeated, the production scale also has an impact. In large-scale production, due to the scale effect, the unit cost may be reduced, and the price may also be reduced.
From this perspective, in order to determine the market price of 5-BOC-4,5,6,7-tetrahydropyrrolido [3,2-C] pyridine-2-carboxylic acid, it is necessary to study the synthesis process, market supply and demand, and production scale in detail, and it often varies from time to time, and it is difficult to hide it from the market.