5-Boc-2-Bromo-6,7-Dihydro-4H-Thiazolo-[5,4-C]Pyridine

The chemical structure of 5-Boc-2-bromo-6,7-dihydro-4H-thiazolo [5,4-c] pyridine, let me tell you in detail.
Among this compound, "5-Boc" refers to the position 5 of the main structure of the compound, which is connected to tert-butoxycarbonyl (Boc). Tert-butoxycarbonyl is a protective group, which is often used in organic synthesis to protect amino isofunctional groups. Its structure is -COOC (CH 🥰), which has specific steric resistance and chemical stability.
"2-bromine" is clearly shown at the second position of the main structure, with a bromine atom attached. As an important halogen atom, bromine atom has high reactivity and can participate in many organic reactions such as nucleophilic substitution and elimination.
"6,7-dihydro-4H-thiazolo [5,4-c] pyridine" indicates that the core main structure of this compound is thiazolo [5,4-c] pyridine, and the positions 6 and 7 are in the dihydro state. The thiazolopyridine structure is an important class of heterocyclic compounds containing nitrogen and sulfur. It is formed by fusing thiazole ring and pyridine ring, and has unique electron cloud distribution and chemical properties. In this structure, the presence of nitrogen and sulfur atoms endows the compound with certain basicity and coordination ability, while the fused ring structure makes it highly stable and rigid.
The overall chemical structure of this compound fuses the characteristics of different functional groups and heterocyclic structures, laying the foundation for its application in organic synthesis, pharmaceutical chemistry and other fields.

5-Boc-2-bromo-6,7-dihydro-4H-thiazolo [5,4-c] pyridine has a wide range of uses. In the field of medicinal chemistry, it can be used as an important organic synthesis intermediate to prepare compounds with specific biological activities. Or by means of organic synthesis, its structure is modified through a series of reactions, and then new drugs can be developed to play therapeutic effects on specific disease targets.
In the field of materials science, due to its unique molecular structure, it endows the substance with specific physical and chemical properties, which can be applied to the creation of functional materials. For example, in the field of optoelectronic materials, when properly designed and modified, it may exhibit unique optical and electrical properties, which can be used in the research and development of optoelectronic devices.
In the field of chemical research, it is often used as a model compound to help scientists delve deeper into the mechanism of organic reactions. With the study of the reaction of its substrate, it can gain insight into the reaction path, intermediate generation and transformation, etc., and contribute to the development of organic synthetic chemistry theory. In short, this compound has important application value in many fields, providing key support for related scientific research and industrial development.

To prepare 5-Boc-2-bromo-6,7-dihydro-4H-thiazolo [5,4-c] pyridine, you can do it according to the following method.
Starting material, take a suitable pyridine derivative, which contains functional groups that can be subsequently converted into thiazole rings and introduced into specific substituents. Using pyridine as a group, the halogen atom is introduced at a specific position, such as the introduction of bromine atom at an appropriate check point of the pyridine ring, which can be achieved by electrophilic substitution reaction. Select a suitable brominating reagent, such as bromine (Br _ 2), react in an inert solvent, such as dichloromethane, under the catalysis of Lewis acid, such as iron tribromide (FeBr _ 3), and control the temperature to precisely locate the bromine atoms to obtain bromopyridine-containing intermediates.
Then, to construct the thiazole ring, introduce reagents containing sulfur and nitrogen. React with the above bromopyridine-containing intermediates with compounds containing thiols and amines. The nucleophilic substitution reaction can be used, and the sulfur atom of the thiol can be used as a nucleophilic reagent to attack the carbon atom connected to the bromine atom in the bromine-containing pyridine to form a carbon-sulfur bond; at the same time, the amine group part reacts with the adjacent position, and through the cyclization process, the thiazole ring structure is constructed to obtain the thiazolopyridine intermediate.
As for the introduction of the Boc protective group, the Boc acid anhydride ((Boc) 2O) is selected as the reagent, and in the presence of an organic base, such as triethylamine (Et 🥰 N), it reacts in an organic solvent, such as Boc anhydride reacts with the amino group to be protected in the intermediate of thiazolopyridine to form a Boc-protected product, namely 5-Boc-2-bromo-6,7-dihydro-4H-thiazolo [5,4-c] pyridine. After each step of the reaction, it needs to be separated and purified, such as column chromatography, to obtain a pure product, and the reaction is advanced one by one to achieve the synthesis of the target product.

I look at what you are asking about "5 - Boc - 2 - Bromo - 6,7 - Dihydro - 4H - Thiazolo - [5,4 - C] Pyridine", which is a rather professional chemical substance. However, it is not easy to know its market price.
Because the market price is often affected by many factors. First, the purity of this substance is crucial. If the purity is high, it is suitable for high-end scientific research experiments, and the price is high; if the purity is slightly lower, it is used for general industrial use, and the price may be slightly reduced. Second, the market supply and demand situation is also critical. If there are many people who want it, and there are few suppliers, the price will rise; on the contrary, if the supply exceeds the demand, the price may decline. Third, the difficulty of preparing this substance also affects its price. If the preparation process is complicated and rare raw materials are required, the cost will be high, and the price will also rise.
Looking at the records of "Tiangong Kaiwu", the prices of various things in the past were also determined by factors such as origin, season, and technology. Today, although this chemical substance is not a category covered in "Tiangong Kaiwu", the reason for its price changes is also similar.
However, I have not obtained the exact market price of this substance. If you want to know more about it, you can consult a professional chemical reagent supplier, who often knows the price of this substance in different purity and specifications; or you can check a professional chemical product trading platform, which may have recent price quotes; you can also refer to academic literature, which may mention relevant procurement costs and other information to help you know the approximate price.

5-Boc-2-bromo-6,7-dihydro-4H-thiazolo [5,4-c] pyridine This substance requires attention to many matters during storage and transportation.
First words storage, it should be stored in a cool and dry place. The reason is that if it is in a high temperature, or its chemical structure changes, it will affect the quality. And humid environment is also a big taboo, water vapor is easy to react with the substance and cause it to deteriorate. This is related to the temperature and humidity of the storage environment, which must be carefully controlled.
Furthermore, the storage place should be well ventilated. Because it may have a special smell, if the ventilation is not smooth, the smell will accumulate, or it will affect the surrounding environment and personnel. And good ventilation can prevent the accumulation of harmful gases in the event of an accident.
And transportation, it is necessary to ensure that the packaging is intact during transportation. The packaging of the item must be able to withstand a certain external force impact to prevent the package from breaking due to collision and bumping during transportation, so that the item leaks.
The transportation tool should also be clean and dry. If there are impurities or moisture in the tool, it can affect the item. And during transportation, it should be avoided to mix with other substances that may react to prevent unexpected chemical reactions.
Furthermore, transport personnel should be familiar with the nature of the item, and in case of emergencies, such as leakage, they can dispose of it quickly and properly according to its characteristics to avoid the expansion of harm. In short, storage and transportation of 5-Boc-2-bromo-6,7-dihydro-4H-thiazolo [5,4-c] pyridine, environmental, packaging, mixed transportation and personnel awareness issues cannot be ignored.