5-aminopyridine-2-carboxamide

5-Aminopyridine-2-formamide, this is an organic compound. It is basic, and its amino group can bind protons. And because it contains amide groups and amino groups, it can participate in hydrogen bonding, or attract each other to molecules or groups that can form hydrogen bonds.
In chemical reactions, amino groups are nucleophilic and can participate in nucleophilic substitution. For example, when reacting with halogenated hydrocarbons, the nitrogen atom of the amino group attacks the carbon atom of the halogenated hydrocarbons nucleophilically, and the halogen atom leaves to form a new nitrogen-containing compound. Amide groups are also reactive. Under specific conditions, hydrolysis can occur. Under the catalysis of acids or bases, amide bonds are broken to form carboxylic acids and ammonia (or ammonium salts), or carboxylic salts and ammon
In terms of physical properties, most of them are solids at room temperature. Due to the interaction of intermolecular hydrogen bonds and van der Waals forces, they have a certain melting point. And because they contain polar groups, they have a certain solubility in polar solvents such as water, but the solubility may be affected by the overall structure and relative molecular weight of the molecule.
Furthermore, this compound is important in the field of organic synthesis and is often used as a key intermediate for the preparation of a variety of drugs, pesticides and functional materials containing pyridine structures. It builds a cornerstone for the synthesis of many compounds and helps to create new substances and optimize their properties.

5-Aminopyridine-2-formamide is also an important intermediate in organic synthesis. There are many common synthesis methods.
First, pyridine-2,5-dicarboxylic acid is used as the starting material. First, pyridine-2,5-dicarboxylic acid is co-heated with sulfinyl chloride to convert its carboxyl group into an acyl chloride group to obtain pyridine-2,5-dicarboxylic chloride. Next, the dicarboxylic acid chloride reacts with excess ammonia water, which can promote the conversion of acyl chloride into an amide group to obtain pyridine-2,5-dicarboxylamide. Then with a suitable reducing agent, such as sodium borohydride-aluminum trichloride system, carefully reduce one of the amide groups to an amino group, then obtain 5-aminopyridine-2-formamide.
Second, use 2-cyano-5-nitropyridine as the starting material. First, 2-cyano-5-nitropyridine is reduced to an amino group with a suitable reducing agent, such as iron-hydrochloric acid system, to obtain 2-cyano-5-aminopyridine. Subsequently, the cyano group is hydrolyzed under acidic or basic conditions, converted into a carboxyl group, and then reacted with thionyl chloride to form an acid chloride, and finally reacted with ammonia to obtain 5-aminopyridine-2-formamide.
Third, 5-halogenated pyridine-2-formamide is used as raw material. If the halogen atom is chlorine, bromine, etc., it can be used in the presence of suitable catalysts, such as palladium catalysts, with amination reagents, such as ammonia, organic amines, etc., under suitable reaction conditions, nucleophilic substitution occurs, and the halogen atom is replaced by an amino group to obtain 5-aminopyridine-2-formamide. All kinds of synthetic methods have their own advantages and disadvantages, and should be carefully selected according to factors such as actual demand, availability of raw materials, and reaction conditions.

5-Aminopyridine-2-formamide is useful in many fields. In the field of medicine, this compound has a unique chemical structure and can interact with specific targets in organisms. Because it contains amino and amide groups, it can participate in a variety of biochemical reactions, and can be used as a key intermediate in drug development. For example, the synthesis of new antibacterial drugs, which combine with specific bacterial proteins by their structure, interfere with bacterial metabolism and achieve antibacterial effect; or in the development of anti-tumor drugs, the cell signaling pathway is precisely regulated to inhibit tumor cell growth.
In the field of materials science, 5-aminopyridine-2-formamide can be used as the cornerstone of building functional materials. Because the groups it contains can form strong interactions with other molecules or material surfaces, or can be used to prepare high-performance adsorption materials. With its adsorption capacity for specific substances, it can adsorb harmful heavy metal ions or organic pollutants in the treatment of environmental pollutants and purify the environment. Furthermore, in the field of electronic materials, it can adjust the electrical properties of materials and prepare materials with special electrical conductivity or photoelectric conversion properties.
In the field of agricultural chemistry, this compound may be used to create new pesticides. With its structure and biological activity, high-efficiency and low-toxicity insecticides or fungicides can be developed. With its unique mechanism of action, it can precisely attack harmful organisms, and has little impact on the environment and non-target organisms, contributing to the sustainable development of agriculture. In conclusion, 5-aminopyridine-2-formamide has great potential in many fields such as medicine, materials, agriculture, etc. With the deepening of research, its application prospect will be broader.

5-Aminopyridine-2-formamide, this is an organic compound. Its physical properties are very interesting, let me tell you in detail.
When it comes to appearance, at room temperature, 5-aminopyridine-2-formamide is mostly in the state of white to off-white crystalline powder, with fine texture and a sense of purity.
As for solubility, it shows certain solubility properties in organic solvents, such as methanol and ethanol. In methanol, polar organic solvents are also used, and 5-aminopyridine-2-formamide can be moderately dissolved in it. This is due to the intermolecular force, and the interaction between solute and solvent molecules promotes the dissolution process. In water, its solubility is relatively limited. Although there are amino groups and amide groups in the molecular structure that can form hydrogen bonds with water, the hydrophobicity of pyridine rings hinders its large-scale dissolution in water to a certain extent.
In terms of melting and boiling point, this compound has a specific melting and boiling point value. The determination of the melting point can help us identify its purity. 5-aminopyridine-2-formamide of high purity has a relatively fixed and sharp melting point. When heated to the melting point temperature, the substance gradually changes from a solid state to a liquid state, and this phase transition process follows the laws of physics. The boiling point reflects the temperature conditions under which it changes from a liquid state to a gaseous state under a specific pressure. However, the boiling point data needs to be accurately determined experimentally and is affected by factors such as environmental pressure.
In addition, the density of 5-aminopyridine-2-formamide is also one of its physical properties. The density value reflects the mass of the substance in a unit volume, which is of great significance for studying its distribution in different media and mixing behavior with other substances.
In summary, the physical properties of 5-aminopyridine-2-formamide, such as appearance, solubility, melting point, density, etc., have a profound impact on its application in organic synthesis, drug development, and other fields. Researchers need to consider it carefully before they can make good use of it.

5-Aminopyridine-2-formamide, the price of this product is difficult to determine in the market. The change in its price depends on multiple ends.
First, the situation of supply and demand is the main reason. If there are many people in the market, but the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price will decline.
Second, the difficulty of its preparation is also related to the price. If its production requires complexity, high consumption, or depends on rare raw materials, the cost will be high, and its price in the market will also be high.
Furthermore, the competition in the market also has an impact. If there are a large number of people competing for the market, the price may be reduced; if the market is monopolized, the price may be high.
Also, changes in the current situation, such as decrees and tax changes, can also cause prices to move. If taxes are imposed, the price may rise; if decrees promote their production, the price may fall.
And in different places, the price is also different. Prosperous cities, logistics is convenient, demand is large, and prices may be remote.
To sum up, in order to know the exact price of 5-aminopyridine-2-formamide, it is necessary to carefully observe the current supply and demand, the preparation situation, the competition of the city, the current situation and the place where it is located.