5-Amino-2,3-dichloropyridine

5-Amino-2,3-dihydroxybenzoic acid, its main use in the era of "Tiangong Kaiwu" is not as clear as in modern times, but it can be discussed as follows from the perspective of ancient times and related knowledge.
In the field of medicine, ancient healers often explored the properties of various plants and stones to treat diseases. 5-Amino-2,3-dihydroxybenzoic acid or because it contains special functional groups, has certain pharmacological activity. In ancient times, herbal ingredients were used as medicine. Although it is difficult to know exactly that this compound has been used at that time, from the perspective of drug exploration, it may be used as a potential medicinal ingredient. For example, many substances containing hydroxyl groups and amino groups can be processed, compatible, or can regulate human qi and blood and solve various diseases.
In the dye industry, dyes in ancient times were mostly derived from nature. This compound contains a specific structure, or can be used as a dye through certain treatment. Ancient printing and dyeing craftsmen pursued very high colors. Natural plants and minerals can be colorful after different processing. 5-Amino-2,3-dihydroxybenzoic acid may be able to dye fabrics with a unique color through special mordant dyeing processes, and its structure may make the color last longer, and it has certain application potential in fabric printing and dyeing.
In alchemy, ancient alchemists were keen on alchemy for longevity or to refine miraculous things. This compound has a special structure, and during the process of alchemy, it may interact with other gold stones and medicines to produce special chemical reactions, or it may be regarded by alchemists as something that can change the properties of alchemy pills, and it has been tried in the practice of alchemy. Although its purpose is impractical, it reflects that it may have participated in the field of ancient chemical exploration.

5-Amino-2,3-dihydroxypyridine, its physical properties are as follows:
This substance is mostly solid at room temperature, and its appearance is often white to light yellow crystalline powder, with a more delicate and uniform texture. Its melting point is within a certain range, about [X] ° C to [X] ° C. This melting point characteristic makes it transition from solid to liquid at a specific temperature.
5-Amino-2,3-dihydroxypyridine has a certain solubility in water in terms of solubility, but the degree of solubility is not very high. Under heating conditions, its solubility in water will increase. For common organic solvents, such as ethanol, acetone, etc., there are also different degrees of solubility. In ethanol, it can be partially dissolved to form a slightly cloudy or clear solution, depending on the ratio of solute to solvent; in acetone, the dissolution state is similar, but the dissolution rate is different from the final dissolution amount or from ethanol.
Its density is about [X] g/cm ³, which reflects its mass per unit volume and determines the difference in density-related properties between it and other substances. In terms of odor, this substance usually has a relatively weak and special smell, not a pungent and unpleasant smell, but a relatively light and unique smell that needs to be smelled closely.
In terms of stability, it can maintain a relatively stable chemical structure in general temperature and humidity environments. However, if exposed to high temperatures, high humidity or specific chemical atmospheres, chemical reactions may occur, causing changes in its structure and properties. For example, in a strongly oxidizing environment, amino or hydroxyl groups in the molecular structure may be oxidized, thereby affecting their physical and chemical properties.

5-Amino-2,3-dihydroxypyridine is an important organic synthesis intermediate, which is widely used in medicine, pesticides, materials and other fields. Its synthesis methods are diverse, and the common ones are as follows:
1. ** Pyridine is used as the starting material **: Pyridine can be obtained through a series of reactions such as nitration, reduction, and hydroxylation. First, pyridine is nitrified to obtain nitropyridine, and then the nitro group is converted into an amino group by reduction, and then a hydroxyl group is introduced through a hydroxylation reaction. The raw materials for this route are easy to obtain, but there are many reaction steps, and the reaction conditions need to be strictly controlled to ensure the yield and selectivity of each step.
2. ** Using cyclization reaction strategy **: Using compounds containing nitrogen and oxygen functional groups as raw materials, pyridine rings are constructed by intramolecular cyclization and amino and hydroxyl groups are introduced. For example, some nitrile or amide compounds containing suitable substituents undergo cyclization reaction under specific catalyst and reaction conditions. This method is relatively simple in steps and has high atomic economy, but it is demanding on the structure of the raw materials and requires careful design of the raw materials.
3. ** With the help of microbial conversion method **: Biocatalytic conversion of substrates using specific microorganisms or their enzymes. Microorganisms are highly specific and selective, and can realize complex chemical reactions under mild conditions. Microbial strains that can recognize specific substrates and catalyze the production of 5-amino-2,3-dihydroxypyridine were selected, and the substrates were converted into target products under the action of enzymes in the microorganisms through fermentation and culture. The method is green and environmentally friendly, and the conditions are mild, but it is difficult to screen suitable microbial strains, and the control of the fermentation process also requires fine operation.

5-Amino-2,3-dihydroxybenzoic acid, this product is in the market, and its price range varies according to various conditions.
Prices in the city often change due to the purity of the quality, the amount of production, and the urgency of the demand. If its quality is high and pure, it is needed by various industries, and there are many seekers and few producers, the price will be high. On the contrary, if the quality is flat and the production is abundant, and there are few applicants, the price will be flat.
Generally speaking, in today's city, 5-amino-2,3-dihydroxybenzoic acid, if it is a commonly used grade in industry, when purchased, the price per gram may be in the range of tens to hundreds of yuan. If it is a high-purity grade, it is suitable for fine scientific research and other fields, and the price per gram may reach several hundred yuan, or even higher.
However, this is only a rough estimate. The actual price must be carefully examined by the market conditions, the asking price of the supplier and the ability of the buyer to negotiate. The business sea changes, and the city has no rules. If you want to know the exact price, you should consult the supplier in person and compare the offer to get a near-real price.

The common storage conditions for 5-amino-2,3-dihydroxypyridine are as follows:
should be placed in a cool, dry and well-ventilated place. This compound contains amino and hydroxyl groups, which are easy to react with moisture and oxygen in the air. A cool environment can reduce its chemical reactivity and avoid reactions such as decomposition caused by excessive temperature; a dry environment can prevent it from deteriorating due to moisture absorption, such as amino groups are easy to form hydrogen bonds with water or hydrate, and then change its chemical structure and properties; good ventilation can disperse harmful gases that may be generated in time to ensure the safety of the storage environment. < Br >
When storing, it should be kept away from fire and heat sources. Because it is more sensitive to heat, high temperature may cause the chemical bonds in the molecule to break and cause decomposition, and the proximity of fire may directly lead to dangerous conditions such as combustion or even explosion.
It needs to be stored separately from the oxidant. This is because the amino group has a certain degree of reductivity and is easily oxidized by the oxidant, and a redox reaction occurs, which changes the chemical properties of the compound and may produce harmful substances in severe cases. < Br >
It should be placed in a sealed container to prevent direct contact with air and reduce the chance of reaction with oxygen, moisture and other impurities in the air, so as to ensure the stability of 5-amino-2,3-dihydroxypyridine during storage and maintain its chemical structure and properties unchanged.