5,7-Dichloro-1H-imidazo[4,5-b]pyridine

5,7-Difluoro-1H-indolo [4,5-b] pyridine has a wide range of uses. In the field of pharmaceutical research and development, it is a key intermediate and plays an important role in the process of creating new drugs. Because it has a unique chemical structure, it can precisely bind to specific targets in organisms, thus exhibiting unique biological activities. Taking the development of anti-cancer drugs as an example, scientists use it to build a drug molecular framework. By modifying its surrounding groups, they can improve the targeting and inhibitory effect of drugs on cancer cells, greatly enhancing the efficacy of drugs and providing a new opportunity to overcome cancer problems.
In the field of materials science, 5,7-difluoro-1H-indolo [4,5-b] pyridine also has important uses. Due to its special electrical and optical properties, it can be used to prepare organic semiconductor materials. These materials can significantly improve device performance in devices such as organic Light Emitting Diodes (OLEDs) and organic field effect transistors (OFETs). For example, in OLEDs, the luminous efficiency and color purity can be optimized, making the display picture clearer and brighter, adding to the progress of display technology.
Furthermore, in the field of chemical synthesis, it is an extremely important synthetic building block. Chemists can use it to build complex molecular structures, expand the boundaries of synthetic chemistry, and help synthesize more novel and unique compounds, injecting new vitality into the development of chemistry.

5,7-Difluoro-1H-indolo [4,5-b] pyridine is an organic compound. Its physical properties are as follows:
In appearance, it is usually a crystalline solid. Due to the existence of various forces between molecules, the molecules are arranged regularly and then crystallized. From the color point of view, when pure, it may be white to light yellow solid, due to the influence of conjugate system and substituents, the light absorption is different.
In terms of melting point, due to the strong intermolecular forces such as nitrogen and fluorine atoms, the formation of hydrogen bonds and van der Waals forces, the melting point is relatively high, roughly in the range of 150 ° C - 250 ° C, depending on the purity and measurement conditions. At the boiling point, due to its relative molecular mass and intermolecular force, the boiling point may be around 300 ° C - 400 ° C, and a higher temperature is required to overcome the intermolecular force to gasify.
In terms of solubility, the compound is an organic weak polar. In common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), it has a certain solubility due to the principle of similar miscibility; but in water, due to the large polar difference, the solubility is poor.
The density may be slightly higher than that of water, due to the close variety and arrangement of atoms in the molecule, and the unit volume mass is larger. In addition, molecules containing conjugated systems may have certain optical activity, and under specific wavelengths of light, they may undergo electronic transitions and exhibit optical properties such as fluorescence, which has potential application value in the field of optoelectronic devices.

The synthesis method of 5% 2C7-difluoro-1H-indolo [4,5-b] pyridine is not directly recorded in the ancient book "Tiangong Kaiwu", but it is based on the current chemical synthesis concept, or there are various paths.
First, it can be combined by the catalytic coupling method of transition metals through pyridine derivatives and fluoroindole intermediates. First, a suitable substituted pyridine substrate is carefully prepared, and then the fluoroindole-containing part is coupled with pyridine under the action of specific metal catalysts such as palladium and nickel to form key carbon-carbon or carbon-nitrogen bonds. This process requires precise regulation of the reaction temperature, solvent and ligand to achieve the ideal yield and selectivity.
Second, it may be possible to pass the strategy of intramolecular cyclization. Starting from the linear precursor with suitable functional groups, the indole-pyridine skeleton is constructed by intracellular nucleophilic substitution or cyclization reaction, and then fluorine atoms are introduced. The introduction of fluorine atoms can use nucleophilic fluorination reagents to replace hydrogen atoms at specific positions under appropriate conditions to complete 5,7-difluorine substitution.
Third, the ortho-site fluorination method guided by the guide group. Introduce a guide group into the pyridine or indole part to guide the fluorine atom to selectively fluorinate at positions 5 and 7 where the steric resistance is suitable and the electron cloud density matches. After the reaction is completed, the guide group is skillfully removed to obtain the target product. Although these methods are not contained in "Tiangongkai", they are all effective ways for the synthesis of 5% 2C7-difluoro-1H-indolo [4,5-b] pyridine in today's organic synthesis chemistry.

I look at your words, and the price mentioned is "5,7-difluoro-1H-indolo [4,5-b] pyridine". However, this product is quite professional, and its price varies depending on many factors such as quality, purity, supply and demand, and provenance.
In the ordinary pharmaceutical market, if it is a product of ordinary purity, or due to the difficulty of preparation, the price per gram may range from tens of gold to hundreds of gold. If the purity is extremely high, it is suitable for high-end scientific research, and its price should rise sharply, per gram or up to thousands of gold.
And it is in different places, due to logistics and taxation, the price is also different. In the prosperous city of Dayi, or due to strong demand and convenient trade, the price may be relatively stable; in remote places, or due to difficult transshipment, the price may be slightly higher.
In addition, the market situation changes, and the state of supply and demand changes at any time. If there are many people and few supply at a time, the price will rise; on the contrary, if the supply exceeds demand, the price will fall.
To know the exact price, you should consult the firm specializing in such chemicals, or check it carefully on a professional trading platform, to get the actual price.

5% 2C7-difluoro-1H-indolo [4,5-b] pyridine This chemical substance should be stored in a cool, dry and well-ventilated place. Due to its nature or potential impact on the environment and human body, it is necessary to keep away from fire, heat sources, and avoid direct sunlight. The humidity of the storage environment should be kept stable to prevent moisture and deterioration.
Because it may have certain chemical activity, it needs to be stored separately from oxidants, acids, alkalis and other substances. It must not be mixed with storage to avoid dangerous chemical reactions. The storage area should be equipped with suitable containment materials to prevent leakage accidents from being handled in time and reduce hazards.
Be careful during handling to prevent damage to packaging and containers. The storage site should be inspected regularly to ensure that the environmental conditions are stable and the packaging is intact, so as to ensure the safety and stability of the chemical during storage and avoid safety hazards or quality changes caused by improper storage.