5 6 Dimethoxy 2 Pyridine 4 Yl Methylene Indan 1 One
pyridine pyrrole pyrazine piperidine piperazine

5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one

    Specifications

    HS Code

    108861

    Chemical Formula C17H15NO3
    Molecular Weight 281.306 g/mol
    Appearance Solid (predicted)

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    General Information
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    Frequently Asked Questions

    As a leading 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 5,6-dimethoxy-2- (pyridine-4-yl) methylene-indane-1-one?
    5,6 -Dimethoxy-2 - (p-methoxy-4-yl) methylene-furan-1-one This substance has a wide range of uses. In the field of medicine, it is often used as a key intermediate. Due to its unique structure, it can participate in a variety of chemical reactions. After modification and transformation, it can prepare compounds with specific biological activities, which is of great significance to the development of new drugs. For example, some drugs with antibacterial and anti-inflammatory effects may be used as starting materials or important links in the synthesis process to build complex drug molecular structures by chemical means.
    In the field of materials science, it also has its own uses. Due to some physical and chemical properties, it may be used to prepare functional materials. Under specific conditions, it can be polymerized or combined with other materials to give materials special properties, such as improving material stability, optical properties, etc., providing new ideas and approaches for the research and development of new materials.
    In the field of organic synthesis, it plays an indispensable role. With its own active groups, it can trigger a series of organic reactions, such as nucleophilic substitution, addition reactions, etc., providing effective methods for constructing complex organic molecular structures. Organic chemists often use this as a basis to design and optimize various synthetic routes, expand the variety and structure of organic compounds, and promote the development of organic synthetic chemistry.
    What are the synthesis methods of 5,6-dimethoxy-2- (pyridine-4-yl) methylene-indane-1-one?
    To prepare 5% 2C6-dimethoxy-2- (p-toluene-4-yl) methylene-naphthalene-1-one, the following ancient methods can be used to find the diameter.
    First, the naphthalene-1-one is used as the starting material. First, it is mixed with an appropriate alkali agent to dissociate the α-hydrogen of naphthalene-1-one to form anion. After adding 5% 2C6-dimethoxy-2-halogen, the two can be obtained by nucleophilic substitution reaction to obtain 5% 2C6-dimethoxy-2-halomethylene-naphthalene-1-one. This halogen is then nucleophilic addition reaction with p-toluene-4-based metal reagents, such as Grignard reagent or lithium reagent, etc., to obtain the target product. When reacting, pay attention to the reaction temperature, reagent ratio and reaction time to prevent side reactions, such as excessive substitution.
    Second, p-toluene-4-yl formaldehyde and 5% 2C6-dimethoxy-2-halogenated naphthalene-1-one are used as raw materials. In a weak base environment, the two perform hydroxyaldehyde condensation reaction. Under the catalysis of base, the carbonyl group of p-toluene-4-yl formaldehyde and the α-hydrogen of naphthalene-1-one generate carbon-carbon double bonds to obtain 5% 2C6-dimethoxy-2 - (p-toluene-4-yl) methylene-naphthalene-1-one. In this process, the strength and dosage of the base, as well as the properties of the reaction solvent, will affect the reaction rate and yield. Fine regulation is required to select mild weak bases, such as potassium carbonate or pyridine, and appropriate solvents, such as ethanol, dichloromethane, etc., to promote the anterograde reaction.
    Third, consider using 5% 2C6-dimethoxy-2-naphthalene-1-one as a substrate, and first convert its carbonyl group to active intermediates such as enol ethers or enamines. Then let this intermediate react with p-toluene-4-yl halides under the catalysis of Lewis acid or transition metals for nucleophilic substitution or coupling. This path can increase the reaction selectivity and reduce side reactions. However, it is necessary to select suitable catalysts, such as aluminum trichloride, cuprous iodide, etc., and control the reaction conditions, such as temperature, time and proportion of reactants, to achieve the ideal yield and purity.
    What are the physicochemical properties of 5,6-dimethoxy-2- (pyridine-4-yl) methylene-indane-1-one?
    5,6-Dimethoxy-2- (p-toluene-4-yl) methylene-pyrroliman- 1-one is a significant compound in the field of organic synthesis. Its physical and chemical properties are unique, let me tell you in detail.
    First talk about its physical properties. Under normal temperature and pressure, this compound is usually in a solid state, and it may be a white to light yellow crystalline powder. This color and morphological characteristics are closely related to the arrangement of atoms in the molecular structure and the distribution of electron clouds. The values of its melting point and boiling point are also determined by the intermolecular forces. There are forces such as van der Waals force and hydrogen bond between molecules, and the strength of these forces directly affects the temperature of the phase transition. The melting point of this compound has been experimentally determined to be in a specific range, and the melting point data can provide a key basis for its purification and identification.
    Re-discuss its chemical properties. In the molecular structure of this compound, groups such as dimethoxy, methylene and pyrromanone give it unique chemical activities. The oxygen atom in the dimethoxy group is rich in lone pairs of electrons, which makes it exhibit a certain nucleophilicity. It can participate in the reaction as a nucleophilic reagent in many chemical reactions. For example, in the nucleophilic substitution reaction, it can interact with suitable electrophilic reagents to realize the substitution of groups, and then derive a series of new compounds. The methylene part, because of its connection to different groups, has an uneven distribution of electron cloud density, so that the surrounding chemical bonds have specific reactivity. In some oxidation or addition reactions, corresponding chemical changes can occur. The pyrromanone ring gives the whole molecule a certain stability, and also participates in some reactions involving the rearrangement of electron clouds on the ring.
    Due to its unique physical and chemical properties, this compound has shown potential application value in many fields such as medicine and materials science. In the field of medicine, its structure and activity characteristics may make it a potential drug lead compound. Through further structural modification and activity screening, it is expected to develop new therapeutic drugs. In the field of materials science, the new materials it participates in the synthesis may have special electrical and optical properties, thus injecting new vitality into the development of related fields.
    What is the market price of 5,6-dimethoxy-2- (pyridine-4-yl) methylene-indan-1-one?
    5% 2C6 -dimethoxy-2 - (p-toluene-4-yl) aminomethyl-pyrimidine-1-one, the price of this substance on the market is difficult to determine. The change in its price depends on various factors and cannot be generalized.
    First, the price of raw materials has a deep impact. If the raw materials required for the preparation of this compound are scarce, or due to changes in weather, geography, and personnel, the output is reduced, or there are many people who want it, the price of raw materials will rise, and the cost of this compound will also rise accordingly. The price on the market will rise as the tide rises. < Br >
    Second, the preparation method is also the key. If the preparation process is complicated, special equipment and exquisite skills are required, and there are a lot of losses in the process, the preparation cost will increase greatly, and the price will also be high. On the contrary, if the process is simple, the cost can be slightly reduced, and the price may be different.
    Third, the market's demand determines the price. If this product is in high demand in medicine, chemical industry and other fields, and there are many people seeking it, but the supply is limited, the price will increase; if the demand is low and the supply exceeds the demand, the price may be downward.
    Fourth, manufacturers and regions also have an impact. Different manufacturers, due to differences in technology, scale, management, different costs, and different pricing. And different regions, transportation costs, tax differences, etc., can cause price changes.
    Therefore, in order to determine the exact price of 5% 2C6-dimethoxy-2- (p-toluene-4-yl) aminomethyl-pyrimidine-1-one in the market, it is necessary to study the raw material market, preparation process, market supply and demand, and the manufacturer's region and many other factors. In combination, a more accurate price can be obtained.
    What are the storage conditions for 5,6-dimethoxy-2- (pyridine-4-yl) methylene-indane-1-one?
    The storage conditions of 5% 2C6-dimethoxy-2- (p-toluene-4-yl) methylene-furan-1-one are the key factors for the chemical substance to maintain its chemical stability, ensure safe use and extend its shelf life.
    The storage conditions are as follows: It should be stored in a cool and well-ventilated place. This is because high temperature can easily cause the substance to chemically react, and even cause decomposition or deterioration. If the storage environment temperature is too high, it may enhance the molecular activity and promote unnecessary reactions, which will affect the quality of the substance. Well-ventilated can avoid its accumulation in local spaces and prevent potential hazards caused by high concentrations. < Br >
    Must be kept away from fires and heat sources. The substance may be flammable or chemically active. In case of fires or heat sources, it is very likely to cause serious accidents such as combustion or even explosion, endangering the safety of storage sites and surrounding areas.
    Should be stored separately from oxidants, acids, bases, etc., and should not be mixed. Due to the chemical structure of the substance, it may react violently with the above-mentioned substances. If it comes into contact with an oxidizing agent, or initiates an oxidation reaction; encounters with acids or bases, or causes the structure of the substance to change due to acid-base reaction, losing its original properties.
    Storage area should be equipped with suitable materials to contain leaks. In order to prevent the occurrence of leakage, it can be dealt with in a timely and effective manner to avoid the spread of leaked substances and cause greater harm to the environment and personnel. Materials such as cotton, sand and other materials can be prepared to quickly absorb leaked liquids and prevent their flow and penetration. Such storage conditions are to ensure the safety and stability of 5% 2C6-dimethoxy-2- (p-toluene-4-yl) methylene-furan-1-one during storage.