5 6 Dichloropyridine 2 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

5,6-Dichloropyridine-2-carboxylic acid

    Specifications

    HS Code

    648389

    Name 5,6 - Dichloropyridine - 2 - carboxylic acid
    Molecular Formula C6H3Cl2NO2
    Molecular Weight 192.00
    Appearance White to off - white solid
    Melting Point 225 - 229 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Pka Value Around 2.5 (approximate, for the carboxylic acid group)

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    General Information
    Where to Buy 5,6-Dichloropyridine-2-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 5,6-Dichloropyridine-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5,6-dichloropyridine-2-carboxylic acid?
    5,6-Dinitrotoluene-2-carboxylic acid, which is mainly used in military and industrial fields. In the military field, it is a key raw material for the manufacture of explosives. Because of its high explosive energy and good explosive properties, it is widely used in the production of shells, bombs, mines and many other munitions. In the industrial field, it is an important intermediate for the synthesis of a variety of fine chemicals. For example, in pharmaceutical synthesis, it can be converted into compounds with specific pharmacological activities through specific chemical reactions, providing a key foundation for drug research and development; in dye synthesis, it can be used as an important starting material for the construction of dye molecular structures, helping to synthesize dye products of different colors and properties.
    This substance is the foundation of warfare attack and defense in the military; in the industrial industry, it is the cornerstone of the development of fine chemicals, and it plays an indispensable role in many fields.
    What are the synthesis methods of 5,6-dichloropyridine-2-carboxylic acid?
    5,6-Dihydroxypyridine-2-carboxylic acid. There are many synthesis methods of this compound, which are described in detail below.
    First, pyridine is used as the starting material. Nitrification of pyridine is first carried out, and nitro groups are introduced into the pyridine ring. A mixed acid system of nitric acid and sulfuric acid is commonly used. After careful control of the reaction temperature and time, nitropyridine can be obtained. Subsequently, nitropyridine is obtained by using reduction methods, such as metal and acid (zinc powder and hydrochloric acid) or catalytic hydrogenation (palladium-carbon catalytic hydrogenation). Then through the diazotization reaction, the amino group is converted into a diazonium salt, followed by the reaction with a hydroxyl-containing reagent, the hydroxyl group is introduced, and then oxidized and other steps can form a carboxyl group at a specific position on the pyridine ring, and finally obtain 5,6-dihydroxypyridine-2-carboxylic acid.
    Second, a suitable heterocyclic compound is used as the starting material. For example, some heterocyclic rings with similar structures of the pyridine ring are selected, and the pyridine ring is constructed through a series of ingenious reactions such as ring opening and ring closing, and hydroxyl and carboxyl groups are introduced at an appropriate stage. This route requires a deep understanding of the reaction mechanism of the heterocyclic ring and precise control of the reaction conditions in order to efficiently synthesize the target product.
    < It can be synthesized under mild conditions using the catalysis of specific microorganisms or enzymes, using suitable substrates as raw materials. This method is green and environmentally friendly, and has high selectivity. However, it is necessary to screen out high-efficiency biocatalysts and optimize biological reaction conditions, such as temperature, pH value, substrate concentration, etc., to improve the yield.
    When synthesizing 5,6-dihydroxypyridine-2-carboxylic acid, each method has its own advantages and disadvantages. Although the chemical synthesis method is complicated, the raw materials are easy to obtain and the reaction conditions are relatively controllable; the biosynthesis method is green and efficient, but it is demanding on the biological system. In actual synthesis, the appropriate synthesis method needs to be carefully selected according to specific needs and conditions.
    What is the market price of 5,6-dichloropyridine-2-carboxylic acid?
    In today's world, the price of goods between shops often changes due to various factors. It is not easy to determine the market price of 5,6-dihydroxy-2-naphthoic acid. The price may vary greatly due to changes in origin, quality, supply and demand.
    If it is roughly studied, it is a genus of chemical raw materials and is widely used in the chemical industry. If the origin is fertile, the output is quite abundant, and the market demand is not booming, the price may flatten. On the contrary, if the origin occasionally changes, resulting in a loss of output and a surge in demand, the price will rise.
    In addition, the difference in quality is also the reason for the price increase and decrease. Refined high-quality products have few impurities and outstanding efficiency, and their price is higher than that of regular products.
    Although the exact price has not been known today, if you want to know the details, you can consult the chemical materials business, brokers, or inquire about the market on various business platforms to get the real price of the current market.
    What are the precautions for storing and transporting 5,6-dichloropyridine-2-carboxylic acid?
    For 5,6-dinitro-2-methoxybenzoic acid, many precautions need to be paid attention to during storage and transportation.
    This substance is highly oxidizing and sensitive. When storing, it should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent danger. Because of its active nature, it is easy to react with other substances, so it should be stored separately from reducing agents, acids, and alkalis, and must not be mixed to avoid accidental chemical reactions. At the same time, the storage place should be equipped with suitable materials to contain leaks so that they can be dealt with in time in case of leakage.
    During transportation, extreme caution is also required. Transportation vehicles must ensure that they have fire and explosion-proof facilities. Drivers and escorts should be familiar with the characteristics of the substance and emergency treatment methods. During transportation, it is necessary to prevent collision and friction, and avoid material leakage caused by damage to packaging containers. The loading and unloading process should be handled with care, and it is strictly forbidden to drop or drag to ensure the integrity of the package. If a leak occurs during transportation, corresponding emergency measures should be taken immediately to evacuate the surrounding people, isolate the leakage area, and notify relevant professionals to deal with it in time.
    In short, 5,6-dinitro-2-methoxybenzoic acid has strict requirements on environmental conditions, storage methods, and transportation operations during storage and transportation. Only by treating each link carefully can we ensure that the safety of personnel and the environment are not endangered.
    What are the physical and chemical properties of 5,6-dichloropyridine-2-carboxylic acids?
    5,6-Dinitrotoluene-2-carboxylic acid, this material property is also quite specific. Its color is often light yellow, such as the color of autumn chrysanthemum, and the texture is crystalline, delicate and regular.
    In terms of its melting point, it is about one hundred and fifty degrees, just like the critical temperature is appropriate. In case of this heat, it will slowly melt and gradually change the shape. The number of boiling points is quite high, and under normal conditions, it is difficult to reach its boiling state.
    In terms of solubility, it is extremely insoluble in water. Water seems to be rejected, but it can gradually melt in organic solvents such as ethanol and ether, just like a wanderer returning home and finding a suitable place.
    Chemical activity is also an important characteristic of it. Because it contains nitro and carboxyl groups, nitro groups have strong oxidizing properties, like hidden sharpness; carboxyl groups are acidic and can neutralize with alkali substances. If it meets sodium hydroxide, it becomes salt and water, just like yin and yang. And under specific conditions, it can participate in many organic reactions, such as esterification reactions, dance with alcohols, and generate different ester compounds. It is an important raw material for organic synthesis and has a wide range of uses in the field of chemical industry.